Bemer-Melchior, Pascale, Bryskier, André, Drugeon, Henri B.
The in vitro activity of rifapentine for 44 clinical isolates of Mycobacterium tuberculosis complex was compared with that of rifampicin using the Bactec radiometric method and the absolute...
Fernández-Roblas, Ricardo, Calvo, Raquel, Esteban, Jaime, Bryskier, André, Soriano, Francisco
The bactericidal activities of two new ketolides, HMR 3004 and HMR 3647, and the potential to develop resistance to these two antibiotics were studied in Gram-positive bacilli. As judged by time-kill...
Romand, Stéphane, Bryskier, André, Moutot, Maya, Derouin, Francis
The efficacy of roxithromycin alone or in combination with pyrimethamine or sulphadiazine was examined in vitro and in a murine model of acute toxoplasmosis. In-vitro studies were performed with MRC5...
Mechanism Underlying Levofloxacin Uptake by Human Polymorphonuclear Neutrophils
Vazifeh, Doina, Bryskier, André, Labro, Marie-Thérèse
The mechanism of radiolabeled levofloxacin ([3H]levofloxacin) uptake by human polymorphonuclear neutrophils (PMNs) was investigated by a classical velocity centrifugation technique. PMNs were...
Rolain, Jean-Marc, Maurin, Max, Bryskier, André, Raoult, Didier
In vitro activities of telithromycin compared to those of erythromycin against Rickettsia spp., Bartonella spp., Coxiella burnetii, and Ehrlichia chaffeensis were determined. Telithromycin was more...
Rastogi, Nalin, Goh, Khye Seng, Berchel, Mylene, Bryskier, André
The in vitro activities of HMR 3647 (telithromycin) and HMR 3004, two novel semisynthetic ketolides, were investigated and compared with that of the reference macrolide drug, clarithromycin, against...
Hoppe, Jörg E., Bryskier, André
When tested by agar dilution on Mueller-Hinton agar supplemented with 5% horse blood, the ketolides HMR 3004 and HMR 3647 were slightly more active (MIC at which 90% of the isolates were inhibited...
Reinert, Ralf René, Bryskier, André, Lütticken, Rudolf
The comparative in vitro activity of HMR 3004 and HMR 3647, new ketolide antibiotics, was tested by a standard agar dilution technique against 221 pneumococcal strains, including isolates with...
Reinert, Ralf René, Lütticken, Rudolf, Bryskier, André, Al-Lahham, Adnan
In a nationwide study in Germany covering 13 clinical microbiology laboratories, a total of 307 Streptococcus pyogenes (mainly pharyngitis) and 333 Streptococcus pneumoniae (respiratory tract...
Clonal Relatedness of Erythromycin-Resistant Streptococcus pyogenes Isolates in Germany
Reinert, Ralf R., Lütticken, Rudolf, Sutcliffe, Joyce A., Tait-Kamradt, Amelia, Cil, Murat Y., Schorn, Holger M., ...
In a nationwide study in Germany, a total of 381 Streptococcus pyogenes were collected. Erythromycin A-resistant strains were characterized for the underlying resistance genotype, showing 55.6% had...
Chollet, Renaud, Chevalier, Jacqueline, Bryskier, André, Pagès, Jean-Marie
The role of the AcrAB-TolC pump in macrolide and ketolide susceptibility in Escherichia coli and Enterobacter aerogenes was studied. Efflux pump inhibitor restored erythromycin, clarithromycin, and...
Mechanism Underlying Levofloxacin Uptake by Human Polymorphonuclear Neutrophils
Vazifeh, Doina, Bryskier, André, Labro, Marie-Thérèse
The mechanism of radiolabeled levofloxacin ([3H]levofloxacin) uptake by human polymorphonuclear neutrophils (PMNs) was investigated by a classical velocity centrifugation technique. PMNs were...
Rolain, Jean-Marc, Maurin, Max, Bryskier, André, Raoult, Didier
In vitro activities of telithromycin compared to those of erythromycin against Rickettsia spp., Bartonella spp., Coxiella burnetii, and Ehrlichia chaffeensis were determined. Telithromycin was more...
Rastogi, Nalin, Goh, Khye Seng, Berchel, Mylene, Bryskier, André
The in vitro activities of HMR 3647 (telithromycin) and HMR 3004, two novel semisynthetic ketolides, were investigated and compared with that of the reference macrolide drug, clarithromycin, against...
Hoppe, Jörg E., Bryskier, André
When tested by agar dilution on Mueller-Hinton agar supplemented with 5% horse blood, the ketolides HMR 3004 and HMR 3647 were slightly more active (MIC at which 90% of the isolates were inhibited...
Reinert, Ralf René, Bryskier, André, Lütticken, Rudolf
The comparative in vitro activity of HMR 3004 and HMR 3647, new ketolide antibiotics, was tested by a standard agar dilution technique against 221 pneumococcal strains, including isolates with...
Reinert, Ralf René, Lütticken, Rudolf, Bryskier, André, Al-Lahham, Adnan
In a nationwide study in Germany covering 13 clinical microbiology laboratories, a total of 307 Streptococcus pyogenes (mainly pharyngitis) and 333 Streptococcus pneumoniae (respiratory tract...
Clonal Relatedness of Erythromycin-Resistant Streptococcus pyogenes Isolates in Germany
Reinert, Ralf R., Lütticken, Rudolf, Sutcliffe, Joyce A., Tait-Kamradt, Amelia, Cil, Murat Y., Schorn, Holger M., ...
In a nationwide study in Germany, a total of 381 Streptococcus pyogenes were collected. Erythromycin A-resistant strains were characterized for the underlying resistance genotype, showing 55.6% had...
Chollet, Renaud, Chevalier, Jacqueline, Bryskier, André, Pagès, Jean-Marie
The role of the AcrAB-TolC pump in macrolide and ketolide susceptibility in Escherichia coli and Enterobacter aerogenes was studied. Efflux pump inhibitor restored erythromycin, clarithromycin, and...
Pankuch, Glenn A., Hoellman, Dianne, Bryskier, André, Lowther, John, Appelbaum, Peter C.
The activity of NXL103 against 108 strains of Haemophilus influenzae was tested using Haemophilus test media (HTM) obtained from various sources. With the exception of those obtained with stored HTM,...