Bliek, Jet, Verde, Gaetano, Callaway, Jonathan, Maas, Saskia M., De Crescenzo, Agostina, Sparago, Angela, ...
Genomic imprinting is an epigenetic phenomenon restricting gene expression in a manner dependent on parent of origin. Imprinted gene products are critical regulators of growth and development, and...
Jet Bliek, Gaetano Verde, Jonathan Callaway, Saskia M Maas, Agostina De Crescenzo, Angela Sparago, ...
Cerrato, Flavia, Sparago, Angela, Verde, Gaetano, De Crescenzo, Agostina, Citro, Valentina, Cubellis, Maria Vittoria, ...
The parent of origin-dependent expression of the IGF2 and H19 genes is controlled by the imprinting centre 1 (IC1) consisting in a methylation-sensitive chromatin insulator. Deletions removing part...
Sparago, Angela, Russo, Silvia, Cerrato, Flavia, Ferraiuolo, Serena, Castorina, Pierangela, Selicorni, Angelo, ...
The imprinted expression of the IGF2 and H19 genes is controlled by the Imprinting Centre 1 (IC1) at chromosome 11p15.5. This is a methylation-sensitive chromatin insulator that works by binding the...
Sparago, Angela, Russo, Silvia, Cerrato, Flavia, Ferraiuolo, Serena, Castorina, Pierangela, Selicorni, Angelo, ...
The imprinted expression of the IGF2 and H19 genes is controlled by the Imprinting Centre 1 (IC1) at chromosome 11p15.5. This is a methylation-sensitive chromatin insulator that works by binding the...
Sparago, Angela, Russo, Silvia, Cerrato, Flavia, Ferraiuolo, Serena, Castorina, Pierangela, Selicorni, Angelo, ...
The imprinted expression of the IGF2 and H19 genes is controlled by the Imprinting Centre 1 (IC1) at chromosome 11p15.5. This is a methylation-sensitive chromatin insulator that works by binding the...
Flavia Cerrato, Angela Sparago, Lucia Farina, Giovanni Battista Ferrero, Margherita Cirillo Silengo, Andrea Riccio
Molecular subtypes and phenotypic expression of Beckwith–Wiedemann syndrome (2005)
Wendy N Cooper, Anita Luharia, Gail A Evans, Hussain Raza, Antonita C Haire, Richard Grundy, ...
Cerrato, Flavia, Sparago, Angela, Matteo, Ines Di, Zou, Xiangang, Dean, Wendy, Sasaki, Hiroyuki, ...
A large cluster of imprinted genes is located on the mouse distal chromosome 7. This cluster is well conserved in humans and its dysregulation results in the overgrowth- and tumour-associated...
Cerrato, Flavia, Sparago, Angela, Di Matteo, Ines, Zou, Xiangang, Dean, Wendy, Sasaki, Hiroyuki, ...
A large cluster of imprinted genes is located on mouse distal chromosome 7. This cluster is well conserved in humans and its dysregulation results in the overgrowth- and tumour-associated...
Cerrato, Flavia, Sparago, Angela, Di Matteo, Ines, Zou, Xiangang, Dean, Wendy, Sasaki, Hiroyuki, ...
A large cluster of imprinted genes is located on mouse distal chromosome 7. This cluster is well conserved in humans and its dysregulation results in the overgrowth- and tumour-associated...
Developmentally regulated functions of the H19 differentially methylated domain (2004)
Vernucci, Maria, Cerrato, Flavia, Pedone, Paolo V., Dandolo, Luisa, Bruni, Carmelo B., Riccio, Andrea
Igf2 and H19 are physically linked imprinted genes. In embryonic liver, their reciprocal expression (paternal for Igf2 and maternal for H19) is controlled by a paternally methylated region (H19 DMD)...
Cerrato, Flavia, Dean, Wendy, Davies, Karen, Kagotani, Kazuhiro, Mitsuya, Kohzoh, Okumura, Katsuzumi, ...
Genomic imprinting in mammals marks the parental alleles in gametes, resulting in differential gene expression in offspring. A number of epigenetic features are associated with imprinted genes. These...
Developmentally regulated functions of the H19 differentially methylated domain (2003)
Vernucci, Maria, Cerrato, Flavia, Pedone, Paolo V., Dandolo, Luisa, Bruni, Carmelo B., Riccio, Andrea
Igf2 and H19 are physically linked imprinted genes. In embryonic liver, their reciprocal expression (paternal for Igf2 and maternal for H19) is controlled by a paternally methylated region (H19 DMD)...
Cerrato, Flavia, Dean, Wendy, Davies, Karen, Kagotani, Kazuhiro, Mitsuya, Kohzoh, Okumura, Katsuzumi, ...
Genomic imprinting in mammals marks the parental alleles in gametes, resulting in differential gene expression in offspring. A number of epigenetic features are associated with imprinted genes. These...
Cerrato, Flavia, Dean, Wendy, Davies, Karen, Kagotani, Kazuhiro, Mitsuya, Kohzoh, Okumura, Katsuzumi, ...
Genomic imprinting in mammals marks the parental alleles in gametes, resulting in differential gene expression in offspring. A number of epigenetic features are associated with imprinted genes. These...
Developmentally regulated functions of the H19 differentially methylated domain (2003)
Vernucci, Maria, Cerrato, Flavia, Pedone, Paolo V., Dandolo, Luisa, Bruni, Carmelo B., Riccio, Andrea
Igf2 and H19 are physically linked imprinted genes. In embryonic liver, their reciprocal expression (paternal for Igf2 and maternal for H19) is controlled by a paternally methylated region (H19 DMD)...
Dathan, Nina, Zaccaro, Laura, Esposito, Sabrina, Isernia, Carla, Omichinski, James G., Riccio, Andrea, ...
The Arabidopsis SUPERMAN (SUP) gene has been shown to be important in maintaining the boundary between stamens and carpels, and is presumed to act by regulating cell proliferation. In this work, we...
Mono- and bi-allelic expression of insulin-like growth factor II gene in human muscle tumors (1994)
Pedone, Paolo V., Tirabosco, Roberto, Cavazzana, Andrea O., Ungaro, Paola, Basso, Giuseppe, Luksch, Roberto, ...
Insulin-like growth factor II (IGF-II) is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal...
The regulatory region of the human plasminogen activator inhibitor type-1 (PAI-1) gene (1988)
Riccio, Andrea, Lund, Leif Røge, Sartorio, Renata, Lania, Arturo, Anderasen, Peter A., Danø, Keld, ...
The human gene for plasminogen activator inhibitor type-1 (PAI-1) has been isolated and its promoter region characterized. PAI-1 regulation by glucocortiooids, transforming growth factor-β (TGF-β)...
The human urokinase-plasminogen activator gene and its promoter (1985)
Riccio, Andrea, Grimaldi, Giovanna, Verde, Pasquale, Sebastio, Gianfranco, Boast, Sharon, Blasi, Francesco
The urokinase type of plasminogen activator (uPA) is subject to regulation by hormones, phorbol esters and oncogenic transformation. This enzyme has been suggested to play a key role in processes...
Dathan, Nina, Zaccaro, Laura, Esposito, Sabrina, Isernia, Carla, Omichinski, James G., Riccio, Andrea, ...
The Arabidopsis SUPERMAN (SUP) gene has been shown to be important in maintaining the boundary between stamens and carpels, and is presumed to act by regulating cell proliferation. In this work, we...
Sperandeo, Maria Pia, Ungaro, Paola, Vernucci, Maria, Pedone, Paolo V., Cerrato, Flavia, Perone, Lucia, ...
Beckwith-Wiedeman syndrome (BWS) and Klippel-Trenaunay-Weber syndrome (KTWS) are different human disorders characterized, among other features, by tissue overgrowth. Deregulation of one or more...
Dathan, Nina, Zaccaro, Laura, Esposito, Sabrina, Isernia, Carla, Omichinski, James G., Riccio, Andrea, ...
The Arabidopsis SUPERMAN (SUP) gene has been shown to be important in maintaining the boundary between stamens and carpels, and is presumed to act by regulating cell proliferation. In this work, we...
Sperandeo, Maria Pia, Ungaro, Paola, Vernucci, Maria, Pedone, Paolo V., Cerrato, Flavia, Perone, Lucia, ...
Beckwith-Wiedeman syndrome (BWS) and Klippel-Trenaunay-Weber syndrome (KTWS) are different human disorders characterized, among other features, by tissue overgrowth. Deregulation of one or more...
Distinct Methylation Changes at the IGF2-H19 Locus in Congenital Growth Disorders and Cancer
Murrell, Adele, Ito, Yoko, Verde, Gaetano, Huddleston, Joanna, Woodfine, Kathryn, Silengo, Margherita Cirillo, ...
The H19 locus acts in vivo as a tumor suppressor
Yoshimizu, Tomomi, Miroglio, Audrey, Ripoche, Marie-Anne, Gabory, Anne, Vernucci, Maria, Riccio, Andrea, ...
The H19 locus belongs to a cluster of imprinted genes that is linked to the human Beckwith-Wiedemann syndrome. The expression of H19 and its closely associated IGF2 gene is frequently deregulated in...