Andrej Rozov

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 (2001)

Sansig,Gilles, Bushell,Trevor J., Clarke,Vernon R. J., Rozov,Andrej, Burnashev,Nail, Portet,Chantal, ...

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7-/-). After the serendipitous discovery of a sensory...

AMPA receptor channels with long-lasting desensitization in bipolar interneurons contribute to synaptic depression in a novel feedback circuit in layer 2/3 of rat neocortex (2001)

Rozov,Andrej, Jerecic,Jasna, Sakmann,Bert, Burnashev,Nail

A novel, local inhibitory circuit in layer 2/3 of rat somatosensory cortex is described that connects pyramidal cells reciprocally with GABAergic vasoactive intestinal polypeptide-immunoreactive...

AMPA receptor channels with long-lasting desensitization in bipolar interneurons contribute to synaptic depression in a novel feedback circuit in layer 2/3 of rat neocortex (2001)

Rozov,Andrej, Jerecic,Jasna, Sakmann,Bert, Burnashev,Nail

A novel, local inhibitory circuit in layer 2/3 of rat somatosensory cortex is described that connects pyramidal cells reciprocally with GABAergic vasoactive intestinal polypeptide-immunoreactive...

Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice (2001)

Hormuzdi,Sheriar G., Pais,Isabel, LeBeau,Fiona E.N., Towers,Stephen K., Rozov,Andrej, Buhl,Eberhard H., ...

Neural processing occurs in parallel in distant cortical areas even for simple perceptual tasks. Associated cognitive binding is believed to occur through the interareal synchronization of rhythmic...

Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice (2001)

Hormuzdi,Sheriar G., Pais,Isabel, LeBeau,Fiona E.N., Towers,Stephen K., Rozov,Andrej, Buhl,Eberhard H., ...

Neural processing occurs in parallel in distant cortical areas even for simple perceptual tasks. Associated cognitive binding is believed to occur through the interareal synchronization of rhythmic...

Conditional restoration of hippocampal synaptic potentiation in GluR-A-deficient mice (2001)

Mack,Volker, Burnashev,Nail, Kaiser,Katharina M. M., Rozov,Andrej, Jensen,Vidar, Hvalby,Øivind, ...

Plasticity of mature hippocampal CA1 synapses is dependent on L-alpha -amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR-A) subunit. In...

Conditional restoration of hippocampal synaptic potentiation in GluR-A-deficient mice (2001)

Mack,Volker, Burnashev,Nail, Kaiser,Katharina M. M., Rozov,Andrej, Jensen,Vidar, Hvalby,Øivind, ...

Plasticity of mature hippocampal CA1 synapses is dependent on L-alpha -amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR-A) subunit. In...

Transmitter release modulation by intracellular Ca2+ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell-specific difference in presynaptic calcium dynamics (2001)

Rozov,Andrej, Burnashev,Nail, Sakmann,Bert, Neher,Erwin

In connections formed by nerve terminals of layer 2/3 pyramidal cells onto bitufted interneurones in young (postnatal day (P)14-15) rat somatosensory cortex, the efficacy and reliability of synaptic...

Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice (2001)

Hormuzdi, Sheriar G., Pais, Isabel, LeBeau, Fiona E.N., Towers, Stephen K., Rozov, Andrej, Buhl, Eberhard H., ...

Neural processing occurs in parallel in distant cortical areas even for simple perceptual tasks. Associated cognitive binding is believed to occur through the interareal synchronization of rhythmic...

Conditional restoration of hippocampal synaptic potentiation in GluR-A-deficient mice (2001)

Mack, Volker, Burnashev, Nail, Kaiser, Katharina M. M., Rozov, Andrej, Jensen, Vidar, Hvalby, Øivind, ...

Plasticity of mature hippocampal CA1 synapses is dependent on L-alpha -amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR-A) subunit. In...

Transmitter release modulation by intracellular Ca2+ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell-specific difference in presynaptic calcium dynamics (2001)

Rozov, Andrej, Burnashev, Nail, Sakmann, Bert, Neher, Erwin

In connections formed by nerve terminals of layer 2/3 pyramidal cells onto bitufted interneurones in young (postnatal day (P)14-15) rat somatosensory cortex, the efficacy and reliability of synaptic...

AMPA receptor channels with long-lasting desensitization in bipolar interneurons contribute to synaptic depression in a novel feedback circuit in layer 2/3 of rat neocortex (2001)

Rozov, Andrej, Jerecic, Jasna, Sakmann, Bert, Burnashev, Nail

A novel, local inhibitory circuit in layer 2/3 of rat somatosensory cortex is described that connects pyramidal cells reciprocally with GABAergic vasoactive intestinal polypeptide-immunoreactive...

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 (2001)

Sansig, Gilles, Bushell, Trevor J., Clarke, Vernon R. J., Rozov, Andrej, Burnashev, Nail, Portet, Chantal, ...

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7-/-). After the serendipitous discovery of a sensory...

Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice (2001)

Hormuzdi, Sheriar G., Pais, Isabel, LeBeau, Fiona E.N., Towers, Stephen K., Rozov, Andrej, Buhl, Eberhard H., ...

Neural processing occurs in parallel in distant cortical areas even for simple perceptual tasks. Associated cognitive binding is believed to occur through the interareal synchronization of rhythmic...

Conditional restoration of hippocampal synaptic potentiation in GluR-A-deficient mice (2001)

Mack, Volker, Burnashev, Nail, Kaiser, Katharina M. M., Rozov, Andrej, Jensen, Vidar, Hvalby, Øivind, ...

Plasticity of mature hippocampal CA1 synapses is dependent on L-alpha -amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR-A) subunit. In...

AMPA receptor channels with long-lasting desensitization in bipolar interneurons contribute to synaptic depression in a novel feedback circuit in layer 2/3 of rat neocortex (2001)

Rozov, Andrej, Jerecic, Jasna, Sakmann, Bert, Burnashev, Nail

A novel, local inhibitory circuit in layer 2/3 of rat somatosensory cortex is described that connects pyramidal cells reciprocally with GABAergic vasoactive intestinal polypeptide-immunoreactive...

Connexin expression in electrically coupled postnatal rat brain neurons (2000)

Venance,Laurent, Rozov,Andrej, Blatow,Maria, Burnashev,Nail, Feldmeyer,Dirk, Monyer,Hannah

Electrical coupling by gap junctions is an important form of cell-to-cell communication in early brain development. Whereas glial cells remain electrically coupled at postnatal stages, adult...

Connexin expression in electrically coupled postnatal rat brain neurons (2000)

Venance,Laurent, Rozov,Andrej, Blatow,Maria, Burnashev,Nail, Feldmeyer,Dirk, Monyer,Hannah

Electrical coupling by gap junctions is an important form of cell-to-cell communication in early brain development. Whereas glial cells remain electrically coupled at postnatal stages, adult...

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 (2000)

Higuchi,Miyoko, Maas,Stefan, Single,Frank N., Hartner,Jochen C., Rozov,Andrej, Burnashev,Nail, ...

RNA editing by site-selective deamination of adenosine to inosine1, 2 alters codons3, 4 and splicing5 in nuclear transcripts6, and therefore protein function. ADAR2 (refs 7, 8) is a candidate...

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 (2000)

Higuchi,Miyoko, Maas,Stefan, Single,Frank N., Hartner,Jochen C., Rozov,Andrej, Burnashev,Nail, ...

RNA editing by site-selective deamination of adenosine to inosine1, 2 alters codons3, 4 and splicing5 in nuclear transcripts6, and therefore protein function. ADAR2 (refs 7, 8) is a candidate...

Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R) (2000)

Single,Frank N., Rozov,Andrej, Burnashev,Nail, Zimmermann,Frank, Hanley,Daniel F., Forrest,Douglas, ...

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutated NR1...

Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R) (2000)

Single,Frank N., Rozov,Andrej, Burnashev,Nail, Zimmermann,Frank, Hanley,Daniel F., Forrest,Douglas, ...

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutated NR1...

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 (2000)

Higuchi, Miyoko, Maas, Stefan, Single, Frank N., Hartner, Jochen C., Rozov, Andrej, Burnashev, Nail, ...

RNA editing by site-selective deamination of adenosine to inosine1, 2 alters codons3, 4 and splicing5 in nuclear transcripts6, and therefore protein function. ADAR2 (refs 7, 8) is a candidate...

Connexin expression in electrically coupled postnatal rat brain neurons (2000)

Venance, Laurent, Rozov, Andrej, Blatow, Maria, Burnashev, Nail, Feldmeyer, Dirk, Monyer, Hannah

Electrical coupling by gap junctions is an important form of cell-to-cell communication in early brain development. Whereas glial cells remain electrically coupled at postnatal stages, adult...

Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R) (2000)

Single, Frank N., Rozov, Andrej, Burnashev, Nail, Zimmermann, Frank, Hanley, Daniel F., Forrest, Douglas, ...

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutated NR1...

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 (2000)

Higuchi, Miyoko, Maas, Stefan, Single, Frank N., Hartner, Jochen C., Rozov, Andrej, Burnashev, Nail, ...

RNA editing by site-selective deamination of adenosine to inosine1, 2 alters codons3, 4 and splicing5 in nuclear transcripts6, and therefore protein function. ADAR2 (refs 7, 8) is a candidate...

Connexin expression in electrically coupled postnatal rat brain neurons (2000)

Venance, Laurent, Rozov, Andrej, Blatow, Maria, Burnashev, Nail, Feldmeyer, Dirk, Monyer, Hannah

Electrical coupling by gap junctions is an important form of cell-to-cell communication in early brain development. Whereas glial cells remain electrically coupled at postnatal stages, adult...

Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R) (2000)

Single, Frank N., Rozov, Andrej, Burnashev, Nail, Zimmermann, Frank, Hanley, Daniel F., Forrest, Douglas, ...

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutated NR1...

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B (1999)

Feldmeyer,Dirk, Kask,Kalev, Brusa,Rossella, Kornau,Hans Christian, Kolhekar,Rohini, Rozov,Andrej, ...

We generated mouse mutants with targeted AMPA receptor (AMPAR) GluR–B subunit alleles, functionally expressed at different levels and deficient in Q/R–site editing. All mutant lines had increased...

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B (1999)

Feldmeyer,Dirk, Kask,Kalev, Brusa,Rossella, Kornau,Hans Christian, Kolhekar,Rohini, Rozov,Andrej, ...

We generated mouse mutants with targeted AMPA receptor (AMPAR) GluR–B subunit alleles, functionally expressed at different levels and deficient in Q/R–site editing. All mutant lines had increased...

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B (1999)

Feldmeyer, Dirk, Kask, Kalev, Brusa, Rossella, Kornau, Hans Christian, Kolhekar, Rohini, Rozov, Andrej, ...

We generated mouse mutants with targeted AMPA receptor (AMPAR) GluR–B subunit alleles, functionally expressed at different levels and deficient in Q/R–site editing. All mutant lines had increased...

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B (1999)

Feldmeyer, Dirk, Kask, Kalev, Brusa, Rossella, Kornau, Hans Christian, Kolhekar, Rohini, Rozov, Andrej, ...

We generated mouse mutants with targeted AMPA receptor (AMPAR) GluR–B subunit alleles, functionally expressed at different levels and deficient in Q/R–site editing. All mutant lines had increased...

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function (1998)

Kask,Kalev, Zamanillo,Daniel, Rozov,Andrej, Burnashev,Nail, Sprengel,Rolf, Seeburg,Peter H.

Calcium permeability of L--amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) in excitatory neurons of the mammalian brain is prevented by coassembly of the GluR-B subunit, which...

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function (1998)

Kask,Kalev, Zamanillo,Daniel, Rozov,Andrej, Burnashev,Nail, Sprengel,Rolf, Seeburg,Peter H.

Calcium permeability of L--amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) in excitatory neurons of the mammalian brain is prevented by coassembly of the GluR-B subunit, which...

Target-cell-specific facilitation and depression in neocortical circuits (1998)

Reyes,Alex, Lujan,R., Rozov,Andrej, Burnashev,Nail, Somogyi,P., Sakmann,Bert

In neocortical circuits, repetitively active neurons evoke unitary postsynaptic potentials (PSPs) whose peak amplitudes either increase (facilitate) or decrease (depress) progressively. To examine...

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo (1998)

Sprengel,Rolf, Suchanek,Bettina, Amico,Carla, Brusa,Rossella, Burnashev,Nail, Rozov,Andrej, ...

NMDA receptors, a class of glutamate-gated cation channels with high Ca2+ conductance, mediate fast transmission and plasticity of central excitatory synapses. We show here that gene-targeted mice...

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo (1998)

Sprengel,Rolf, Suchanek,Bettina, Amico,Carla, Brusa,Rossella, Burnashev,Nail, Rozov,Andrej, ...

NMDA receptors, a class of glutamate-gated cation channels with high Ca2+ conductance, mediate fast transmission and plasticity of central excitatory synapses. We show here that gene-targeted mice...

Facilitation of currents through rat Ca2+ permeable AMPA receptor channels by activity-dependent relief from polyamine block (1998)

Rozov,Andrej, Zilberter,Yuri, Wollmuth,Lonnie P., Burnashev,Nail

In outside-out patches excised from human embryonic kidney (HEK) 293 cells expressing Ca2+-permeable -amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptor (AMPAR) channels, currents activated by...

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function (1998)

Kask, Kalev, Zamanillo, Daniel, Rozov, Andrej, Burnashev, Nail, Sprengel, Rolf, Seeburg, Peter H.

Calcium permeability of L--amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) in excitatory neurons of the mammalian brain is prevented by coassembly of the GluR-B subunit, which...

Target-cell-specific facilitation and depression in neocortical circuits (1998)

Reyes, Alex, Lujan, R., Rozov, Andrej, Burnashev, Nail, Somogyi, P., Sakmann, Bert

In neocortical circuits, repetitively active neurons evoke unitary postsynaptic potentials (PSPs) whose peak amplitudes either increase (facilitate) or decrease (depress) progressively. To examine...

Facilitation of currents through rat Ca2+ permeable AMPA receptor channels by activity-dependent relief from polyamine block (1998)

Rozov, Andrej, Zilberter, Yuri, Wollmuth, Lonnie P., Burnashev, Nail

In outside-out patches excised from human embryonic kidney (HEK) 293 cells expressing Ca2+-permeable -amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptor (AMPAR) channels, currents activated by...

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo (1998)

Sprengel, Rolf, Suchanek, Bettina, Amico, Carla, Brusa, Rossella, Burnashev, Nail, Rozov, Andrej, ...

NMDA receptors, a class of glutamate-gated cation channels with high Ca2+ conductance, mediate fast transmission and plasticity of central excitatory synapses. We show here that gene-targeted mice...

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function (1998)

Kask, Kalev, Zamanillo, Daniel, Rozov, Andrej, Burnashev, Nail, Sprengel, Rolf, Seeburg, Peter H.

Calcium permeability of L--amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) in excitatory neurons of the mammalian brain is prevented by coassembly of the GluR-B subunit, which...

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo (1998)

Sprengel, Rolf, Suchanek, Bettina, Amico, Carla, Brusa, Rossella, Burnashev, Nail, Rozov, Andrej, ...

NMDA receptors, a class of glutamate-gated cation channels with high Ca2+ conductance, mediate fast transmission and plasticity of central excitatory synapses. We show here that gene-targeted mice...

Select Overexpression of Homer1a in Dorsal Hippocampus Impairs Spatial Working Memory

Celikel, Tansu, Marx, Verena, Freudenberg, Florian, Zivkovic, Aleksandar, Resnik, Evgeny, Hasan, Mazahir T., ...

Long Homer proteins forge assemblies of signaling components involved in glutamate receptor signaling in postsynaptic excitatory neurons, including those underlying synaptic transmission and...