Shultzaberger, Ryan K., Roberts, Lindsey R., Lyakhov, Ilya G., Sidorov, Igor A., Stephen, Andrew G., Fisher, Robert J., ...
Individual protein binding sites on DNA can be measured in bits of information. This information is related to the free energy of binding by the second law of thermodynamics, but binding kinetics...
Antony, Smitha, Marchand, Christophe, Stephen, Andrew G., Thibaut, Laurent, Agama, Keli K., Fisher, Robert J., ...
By enzymatically hydrolyzing the terminal phosphodiester bond at the 3′-ends of DNA breaks, tyrosyl-DNA phosphodiesterase (Tdp1) repairs topoisomerase-DNA covalent complexes and processes the DNA...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides (2006)
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of this activity, it plays a crucial role...
Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins (2006)
Cruceanu, Margareta, Urbaneja, Maria A., Hixson, Catherine V., Johnson, Donald G., Datta, Siddhartha A., Fivash, Matthew J., ...
The Gag polyprotein of HIV-1 is essential for retroviral replication and packaging. The nucleocapsid (NC) protein is the primary region for the interaction of Gag with nucleic acids. In this study,...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides (2006)
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
Yang, Quan-en, Stephen, Andrew G., Adelsberger, Joseph W., Roberts, Paula E., Zhu, Weimin, Currens, Michael J., ...
The interaction between human immunodeficiency virus type 1 (HIV-1) gp120 and the CD4 receptor is highly specific and involves relatively small contact surfaces on both proteins according to crystal...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of this activity, it plays a crucial role...
Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins
Cruceanu, Margareta, Urbaneja, Maria A., Hixson, Catherine V., Johnson, Donald G., Datta, Siddhartha A., Fivash, Matthew J., ...
The Gag polyprotein of HIV-1 is essential for retroviral replication and packaging. The nucleocapsid (NC) protein is the primary region for the interaction of Gag with nucleic acids. In this study,...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
Yang, Quan-en, Stephen, Andrew G., Adelsberger, Joseph W., Roberts, Paula E., Zhu, Weimin, Currens, Michael J., ...
The interaction between human immunodeficiency virus type 1 (HIV-1) gp120 and the CD4 receptor is highly specific and involves relatively small contact surfaces on both proteins according to crystal...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of this activity, it plays a crucial role...
Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins
Cruceanu, Margareta, Urbaneja, Maria A., Hixson, Catherine V., Johnson, Donald G., Datta, Siddhartha A., Fivash, Matthew J., ...
The Gag polyprotein of HIV-1 is essential for retroviral replication and packaging. The nucleocapsid (NC) protein is the primary region for the interaction of Gag with nucleic acids. In this study,...
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., ...
Antony, Smitha, Marchand, Christophe, Stephen, Andrew G., Thibaut, Laurent, Agama, Keli K., Fisher, Robert J., ...
By enzymatically hydrolyzing the terminal phosphodiester bond at the 3′-ends of DNA breaks, tyrosyl-DNA phosphodiesterase (Tdp1) repairs topoisomerase-DNA covalent complexes and processes the DNA...
Correlation between binding rate constants and individual information of E. coli Fis binding sites
Shultzaberger, Ryan K., Roberts, Lindsey R., Lyakhov, Ilya G., Sidorov, Igor A., Stephen, Andrew G., Fisher, Robert J., ...
Individual protein binding sites on DNA can be measured in bits of information. This information is related to the free energy of binding by the second law of thermodynamics, but binding kinetics...
Stephen, Andrew G., Datta, Siddhartha A.K., Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Turner, Kevin B., ...
The interaction of the HIV Gag polyprotein with nucleic acid is a critical step in the assembly of viral particles. The Gag polyprotein is composed of the matrix (MA), capsid (CA), and nucleocapsid...
Molecular Characterization of Feline Immunodeficiency Virus Budding▿
Luttge, Benjamin G., Shehu-Xhilaga, Miranda, Demirov, Dimiter G., Adamson, Catherine S., Soheilian, Ferri, Nagashima, Kunio, ...
Infection of domestic cats with feline immunodeficiency virus (FIV) is an important model system for studying human immunodeficiency virus type 1 (HIV-1) infection due to numerous similarities in...
Crist, Rachael M., Datta, Siddhartha A. K., Stephen, Andrew G., Soheilian, Ferri, Mirro, Jane, Fisher, Robert J., ...
Expression of the retroviral Gag protein leads to formation of virus-like particles in mammalian cells. In vitro and in vivo experiments show that nucleic acid is also required for particle assembly....