Pezacki, John, Sagan, Selena M, Tonary, Angela M, Rouleau, Yanouchka, Bélanger, Sylvie, Supekova, Lubica, ...
Abstract Background Hepatitis C virus (HCV) infection is a global health problem. A number of studies have implicated a direct role of cellular lipid metabolism in the HCV life cycle and inhibitors...
A Gene Wiki for Community Annotation of Gene Function (2008)
Camilo Orozco, James Goodale, Chunlei Wu, Serge Batalov, Tim J. Vickers, ...
Expression analysis of G Protein-Coupled Receptors in mouse macrophages (2008)
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
Abstract Background Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic...
Genetical Genomics: Spotlight on QTL Hotspots (2008)
Breitling, Rainer, Li, Yang, Tesson, Bruno M., Fu, Jingyuan, Wu, Chunlei, Wiltshire, Tim, ...
Bystrykh, Leonid, Weersing, Ellen, Dontje, Bert, Sutton, Sue, Pletcher, Mathew T., Wiltshire, Tim, ...
We combined large-scale mRNA expression analysis and gene mapping to identify genes and loci that control hematopoietic stem cell (HSC) function. We measured mRNA expression levels in purified HSCs...
Phillip Mcclurg, Mathew T Pletcher, Tim Wiltshire, Andrew I Su, Andrew I Su
© 2006McClurg et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Gene Expression Evolves Faster in Narrowly than in Broadly Expressed Mammalian Genes (2005)
Yang, Jing, Su, Andrew I., Li, Wen-Hsiung
Despite much recent interest, it remains unclear what determines the rate of evolution of gene expression. To study this issue we develop a new measure, called "Expression Conservation Index" (ECI),...
Gene Expression Evolves Faster in Narrowly Than in Broadly Expressed Mammalian Genes (2005)
Yang, Jing, Su, Andrew I., Li, Wen-Hsiung
Despite much recent interest, it remains unclear what determines the rate of evolution of gene expression. To study this issue we develop a new measure, called “Expression Conservation Index”...
Gene Expression Evolves Faster in Narrowly than in Broadly Expressed Mammalian Genes (2005)
Yang, Jing, Su, Andrew I., Li, Wen-Hsiung
Despite much recent interest, it remains unclear what determines the rate of evolution of gene expression. To study this issue we develop a new measure, called "Expression Conservation Index" (ECI),...
Use of a Dense Single Nucleotide Polymorphism Map for In Silico Mapping in the Mouse (2004)
Mathew T. Pletcher, Philip McClurg, Serge Batalov, Andrew I. Su, S. Whitney Barnes, Erica Lagler, ...
Rapid expansion of available data, both phenotypic and genotypic, for multiple strains of mice has enabled the development of new methods to interrogate the mouse genome for functional genetic...
Applications of a Rat Multiple Tissue Gene Expression Data Set (2004)
Walker, John R., Su, Andrew I., Self, David W., Hogenesch, John B., Lapp, Hilmar, Maier, Rainer, ...
With the sequencing and assembly of the rat genome comes the difficult task of assigning functions to genes. Tissue localization of gene expression gives some information about the potential role of...
Michael D. Conkright, Ernesto Guzmán, Lawrence Flechner, Andrew I. Su, John B. Hogenesch, Marc Montminy, ...
stimulate cooperative interactions with TFIID that facilitate recruitment of RNA polymerase II complexes (Horikoshi et al., 1988). In this regard, CREB has been found to interact with the hTAFII130...
Functional Annotation of RIKEN Mouse cDNA Clones Using GNF Expression Atlas (2003)
Batalov, Serge, Su, Andrew I., Ching, Keith A., Fletcher, Colin F.
Genomic analysis of the host response to hepatitis C virus infection
Su, Andrew I., Pezacki, John P., Wodicka, Lisa, Brideau, Amy D., Supekova, Lubica, Thimme, Robert, ...
We have examined the progression of hepatitis C virus (HCV) infections by gene expression analysis of liver biopsies in acutely infected chimpanzees that developed persistent infection, transient...
Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators
Wu, Chunlei, Delano, David L., Mitro, Nico, Su, Stephen V., Janes, Jeff, McClurg, Phillip, ...
Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene...
Expression analysis of G Protein-Coupled Receptors in mouse macrophages
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
A Gene Wiki for Community Annotation of Gene Function
Huss, Jon W, Orozco, Camilo, Goodale, James, Wu, Chunlei, Batalov, Serge, Vickers, Tim J, ...
This manuscript describes the creation of comprehensive gene wiki, seeded with data from public domain sources, which will enable and encourage community annotation of gene function.
Genetical Genomics: Spotlight on QTL Hotspots
Breitling, Rainer, Li, Yang, Tesson, Bruno M., Fu, Jingyuan, Wu, Chunlei, Wiltshire, Tim, ...
Pezacki, John Paul, Sagan, Selena M, Tonary, Angela M, Rouleau, Yanouchka, Bélanger, Sylvie, Supekova, Lubica, ...
Williams, Richard, Lim, Jackie E., Harr, Bettina, Wing, Claudia, Walters, Ryan, Distler, Margaret G., ...
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV)...