Andrew J. Murphy

Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections (2008)

Towne, Charles Fenton, York, Ian A., Neijssen, Joost J., Karow, Margaret L., Murphy, Andrew J., Valenzuela, David M., ...

Previous experiments using enzyme inhibitors, cell lysates, and purified enzyme have suggested that puromycin-sensitive aminopeptidase (PSA) plays a role in creating and destroying MHC class...

Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation (2005)

Towne, Charles Fenton, York, Ian A., Neijssen, Joost J., Karow, Margaret L., Murphy, Andrew J., Valenzuela, David M., ...

To detect viral infections and tumors, CD8+ T lymphocytes monitor cells for the presence of antigenic peptides bound to MHC class I molecules. The majority of MHC class I-presented peptides are...

Development of homogeneous and heterogeneous epoxidation catalysts using simple Mn complexes and peracetic acid / (2005)

Murphy, Andrew J.

Submitted to the Department of Chemistry.

Development of homogeneous and heterogeneous epoxidation catalysts using simple Mn(II) [superscript] complexes and peracetic acid / (2005)

Murphy, Andrew J., Stack, Daniel Advisor

Submitted to the Department of Chemistry.

AFRPL Graphite Performance Prediction Program. Volume I. Recommendations for a Standardized Analytic Procedure for MX Nozzle Throat Recession Calculations. (2002)

Murphy,Andrew J., Chu,Edward K., Kesselring,John P.

A survey was taken of five solid propellant motor contractors to review current analytic techniques used to predict graphite nozzle material response. Several solutions for a baseline nozzle were...

Plate Tectonics and the Discrimination of Underground Explosions from Earthquakes. (2002)

Murphy, Andrew J., Sykes, Lynn R.

During the term of this contract, research was carried out in the following areas of interest to the contract: (1) A study of the velocity structure under the Tibetan Plateau using at least ten...

Material Performance of Carbon Phenolic Ablators and Pyrolytic Graphite Coatings in Nozzles Subjected to Multiple Pulse Duty Cycles. (1998)

Wool,Mitchell R., Baker,Duane L., Murphy,Andrew J.

Measurements and analysis of the thermal and ablative response of five multiple pulse duty cycle rocket nozzles were performed. Nozzles were fired on a solid propellant simulator with a test stream...

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Gale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., ...

Vascular development depends on the highly coordinated actions of a variety of angiogenic regulators, most of which apparently act downstream of vascular endothelial growth factor (VEGF). One...

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Gale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., ...

Vascular development depends on the highly coordinated actions of a variety of angiogenic regulators, most of which apparently act downstream of vascular endothelial growth factor (VEGF). One...

Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5

Macdonald, Lynn E., Wortley, Katherine E., Gowen, Lori C., Anderson, Keith D., Murray, Jane D., Poueymirou, William T., ...

We identified a glycoprotein hormone β-subunit (OGH, also called GPB5) that, as a heterodimer with the α-subunit GPA2, serves as a second ligand for the thyroid-stimulating hormone receptor. Mice...

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

Dominguez, Melissa G., Hughes, Virginia C., Pan, Li, Simmons, Mary, Daly, Christopher, Anderson, Keith, ...

Development of the vascular system depends on the highly coordinated actions of a variety of angiogenic regulators. Several of these regulators are members of the tyrosine kinase superfamily,...

CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors

Shmelkov, Sergey V., Butler, Jason M., Hooper, Andrea T., Hormigo, Adilia, Kushner, Jared, Milde, Till, ...

Colon cancer stem cells are believed to originate from a rare population of putative CD133+ intestinal stem cells. Recent publications suggest that a small subset of colon cancer cells expresses...

(Re)solving space and time: fulfilment issues in online grocery retailing

Andrew J Murphy

There has been much hype and speculation in the media and in academe on the vitality and future of the 'Internet economy'. In this paper the author uses case studies from Britain, Canada, New Zealand...