Simmons, Graham, Rennekamp, Andrew J., Chai, Ning, Vandenberghe, Luk H., Riley, James L., Bates, Paul
Folate receptor alpha (FRα) has been described as a factor involved in mediating Ebola virus entry into cells (6). Furthermore, it was suggested that interaction with FRα results in internalization...
Simmons, Graham, Reeves, Jacqueline D., Rennekamp, Andrew J., Amberg, Sean M., Piefer, Andrew J., Bates, Paul
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a rapidly emerging pathogen with potentially serious consequences for public health. Here we describe conditions that result not...
Marzi, Andrea, Gramberg, Thomas, Simmons, Graham, Möller, Peggy, Rennekamp, Andrew J., Krumbiegel, Mandy, ...
The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of pathogens interacting with these attachment factors is incompletely defined. Here we show that DC-SIGN and DC-SIGNR...
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
Simmons, Graham, Gosalia, Dhaval N., Rennekamp, Andrew J., Reeves, Jacqueline D., Diamond, Scott L., Bates, Paul
Severe acute respiratory syndrome (SARS) is caused by an emergent coronavirus (SARS-CoV), for which there is currently no effective treatment. SARS-CoV mediates receptor binding and entry by its...
Simmons, Graham, Rennekamp, Andrew J., Chai, Ning, Vandenberghe, Luk H., Riley, James L., Bates, Paul
Folate receptor alpha (FRα) has been described as a factor involved in mediating Ebola virus entry into cells (6). Furthermore, it was suggested that interaction with FRα results in internalization...
Simmons, Graham, Reeves, Jacqueline D., Rennekamp, Andrew J., Amberg, Sean M., Piefer, Andrew J., Bates, Paul
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a rapidly emerging pathogen with potentially serious consequences for public health. Here we describe conditions that result not...
Marzi, Andrea, Gramberg, Thomas, Simmons, Graham, Möller, Peggy, Rennekamp, Andrew J., Krumbiegel, Mandy, ...
The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of pathogens interacting with these attachment factors is incompletely defined. Here we show that DC-SIGN and DC-SIGNR...
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
Simmons, Graham, Gosalia, Dhaval N., Rennekamp, Andrew J., Reeves, Jacqueline D., Diamond, Scott L., Bates, Paul
Severe acute respiratory syndrome (SARS) is caused by an emergent coronavirus (SARS-CoV), for which there is currently no effective treatment. SARS-CoV mediates receptor binding and entry by its...
Hofmann, Heike, Simmons, Graham, Rennekamp, Andrew J., Chaipan, Chawaree, Gramberg, Thomas, Heck, Elke, ...
We have recently demonstrated that the severe acute respiratory syndrome coronavirus (SARS-CoV) receptor angiotensin converting enzyme 2 (ACE2) also mediates cellular entry of the newly discovered...
Chromatin Profiling of Epstein-Barr Virus Latency Control Region▿
Day, Latasha, Chau, Charles M., Nebozhyn, Michael, Rennekamp, Andrew J., Showe, Michael, Lieberman, Paul M.
Epstein-Barr virus (EBV) escapes host immunity by the reversible and epigenetic silencing of immunogenic viral genes. We previously presented evidence that a dynamic chromatin domain, which we have...
Wiedmer, Andreas, Wang, Pu, Zhou, Jing, Rennekamp, Andrew J., Tiranti, Valeria, Zeviani, Massimo, ...
Disruption of cellular metabolic processes and usurpation of host proteins are hallmarks of herpesvirus lytic infection. Epstein-Barr virus (EBV) lytic replication is initiated by the immediate-early...