Andrew L. Darrow

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...

Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...

A novel serine protease predominately expressed in macrophages.

Chen, Cailin, Darrow, Andrew L, Qi, Jian-Shen, D'Andrea, Michael R, Andrade-Gordon, Patricia

We have identified a novel serine protease designated EOS by sequence identity searches. The deduced protein contains 284 amino acids with an active form containing 248 amino acids starting from an...

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...

Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...

A novel serine protease predominately expressed in macrophages.

Chen, Cailin, Darrow, Andrew L, Qi, Jian-Shen, D'Andrea, Michael R, Andrade-Gordon, Patricia

We have identified a novel serine protease designated EOS by sequence identity searches. The deduced protein contains 284 amino acids with an active form containing 248 amino acids starting from an...