Luminal particles within cellular microtubules
Garvalov, Boyan K., Zuber, Benoît, Bouchet-Marquis, Cédric, Kudryashev, Mikhail, Gruska, Manuela, Beck, Martin, ...
The regulation of microtubule dynamics is attributed to microtubule-associated proteins that bind to the microtubule outer surface, but little is known about cellular components that may associate...
Cyrklaff, Marek, Kudryashev, Mikhail, Leis, Andrew, Leonard, Kevin, Baumeister, Wolfgang, Menard, Robert, ...
Microtubules are dynamic cytoskeletal structures important for cell division, polarity, and motility and are therefore major targets for anticancer and antiparasite drugs. In the invasive forms of...
Cryo-electron tomography of cells: connecting structure and function
Lučić, Vladan, Leis, Andrew, Baumeister, Wolfgang
Cryo-electron tomography (cryo-ET) allows the visualization of cellular structures under close-to-life conditions and at molecular resolution. While it is inherently a static approach, yielding...
Hoffmann, Christian, Leis, Andrew, Niederweis, Michael, Plitzko, Jürgen M., Engelhardt, Harald
The cell walls of mycobacteria form an exceptional permeability barrier, and they are essential for virulence. They contain extractable lipids and long-chain mycolic acids that are covalently linked...
Chromatin Organization and Radio Resistance in the Bacterium Gemmata obscuriglobus▿ †
Lieber, Arnon, Leis, Andrew, Kushmaro, Ariel, Minsky, Abraham, Medalia, Ohad
The organization of chromatin has a major impact on cellular activities, such as gene expression. For bacteria, it was suggested that the spatial organization of the genetic material correlates with...