Andrew Preston

Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica (2003)

Parkhill,Julian, Sebaihia,Mohammed, Preston,Andrew, Murphy,Lee D., Thomson,Nicholas, Harris,David E., ...

Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative -proteobacteria that colonize the respiratory tracts of mammals. B. pertussis is a...

Genetic Basis for Lipopolysaccharide O-Antigen Biosynthesis in Bordetellae

Preston, Andrew, Allen, Andrew G., Cadisch, Joanna, Thomas, Richard, Stevens, Kim, Churcher, Carol M., ...

Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella...

Multiple Roles for Bordetella Lipopolysaccharide Molecules during Respiratory Tract Infection

Harvill, Eric T., Preston, Andrew, Cotter, Peggy A., Allen, Andrew G., Maskell, Duncan J., Miller, Jeff F.

Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica are closely related subspecies that cause respiratory tract infections in humans and other mammals and express many...

Role of Bordetella O Antigen in Respiratory Tract Infection

Burns, Valorie C., Pishko, Elizabeth J., Preston, Andrew, Maskell, Duncan J., Harvill, Eric T.

Lipopolysaccharide (LPS), as the major surface molecule of gram-negative bacteria, interacts with the host in complex ways, both inducing and protecting against aspects of inflammatory and adaptive...

Genomic and Genetic Analysis of Bordetella Bacteriophages Encoding Reverse Transcriptase-Mediated Tropism-Switching Cassettes

Liu, Minghsun, Gingery, Mari, Doulatov, Sergei R., Liu, Yichin, Hodes, Asher, Baker, Stephen, ...

Liu et al. recently described a group of related temperate bacteriophages that infect Bordetella subspecies and undergo a unique template-dependent, reverse transcriptase-mediated tropism switching...

pagP Is Required for Resistance to Antibody-Mediated Complement Lysis during Bordetella bronchiseptica Respiratory Infection

Pilione, Mylisa R., Pishko, Elizabeth J., Preston, Andrew, Maskell, Duncan J., Harvill, Eric T.

To efficiently colonize and persist in the lower respiratory tract, bacteria must survive multiple host immune mechanisms. Bordetella bronchiseptica is a gram-negative respiratory pathogen that...

Bordetella pertussis: the intersection of genomics and pathobiology

Preston, Andrew

THERE HAS BEEN MUCH RECENT CONCERN over an increasing incidence of pertussis despite high levels of vaccine coverage of infants. Many reports have documented that much of the increased incidence is...

Comparative Toll-Like Receptor 4-Mediated Innate Host Defense to Bordetella Infection

Mann, Paul B., Wolfe, Daniel, Latz, Eicke, Golenbock, Douglas, Preston, Andrew, Harvill, Eric T.

Bordetella pertussis, B. parapertussis, and B. bronchiseptica are closely related species associated with respiratory disease in humans and other mammals. While B. bronchiseptica has a wide host...

Genetic Basis for Lipopolysaccharide O-Antigen Biosynthesis in Bordetellae

Preston, Andrew, Allen, Andrew G., Cadisch, Joanna, Thomas, Richard, Stevens, Kim, Churcher, Carol M., ...

Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella...

Multiple Roles for Bordetella Lipopolysaccharide Molecules during Respiratory Tract Infection

Harvill, Eric T., Preston, Andrew, Cotter, Peggy A., Allen, Andrew G., Maskell, Duncan J., Miller, Jeff F.

Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica are closely related subspecies that cause respiratory tract infections in humans and other mammals and express many...

Role of Bordetella O Antigen in Respiratory Tract Infection

Burns, Valorie C., Pishko, Elizabeth J., Preston, Andrew, Maskell, Duncan J., Harvill, Eric T.

Lipopolysaccharide (LPS), as the major surface molecule of gram-negative bacteria, interacts with the host in complex ways, both inducing and protecting against aspects of inflammatory and adaptive...

Genomic and Genetic Analysis of Bordetella Bacteriophages Encoding Reverse Transcriptase-Mediated Tropism-Switching Cassettes

Liu, Minghsun, Gingery, Mari, Doulatov, Sergei R., Liu, Yichin, Hodes, Asher, Baker, Stephen, ...

Liu et al. recently described a group of related temperate bacteriophages that infect Bordetella subspecies and undergo a unique template-dependent, reverse transcriptase-mediated tropism switching...

pagP Is Required for Resistance to Antibody-Mediated Complement Lysis during Bordetella bronchiseptica Respiratory Infection

Pilione, Mylisa R., Pishko, Elizabeth J., Preston, Andrew, Maskell, Duncan J., Harvill, Eric T.

To efficiently colonize and persist in the lower respiratory tract, bacteria must survive multiple host immune mechanisms. Bordetella bronchiseptica is a gram-negative respiratory pathogen that...

Bordetella pertussis: the intersection of genomics and pathobiology

Preston, Andrew

THERE HAS BEEN MUCH RECENT CONCERN over an increasing incidence of pertussis despite high levels of vaccine coverage of infants. Many reports have documented that much of the increased incidence is...

Comparative Toll-Like Receptor 4-Mediated Innate Host Defense to Bordetella Infection

Mann, Paul B., Wolfe, Daniel, Latz, Eicke, Golenbock, Douglas, Preston, Andrew, Harvill, Eric T.

Bordetella pertussis, B. parapertussis, and B. bronchiseptica are closely related species associated with respiratory disease in humans and other mammals. While B. bronchiseptica has a wide host...

Expression of the Primary Carbohydrate Component of the Bordetella bronchiseptica Biofilm Matrix Is Dependent on Growth Phase but Independent of Bvg Regulation†

Irie, Yasuhiko, Preston, Andrew, Yuk, Ming H.

We previously showed that the Bvg virulence control system regulates biofilm formation in Bordetella bronchiseptica (Y. Irie, S. Mattoo, and M. H. Yuk, J. Bacteriol. 186:5692-5698, 2004). Analyses of...

Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronic acid 2-epimerases from respiratory pathogens

Westman, Erin L., Mcnally, David J., Rejzek, Martin, Miller, Wayne L., Kannathasan, Vellupillai Sri, Preston, Andrew, ...

The heteropolymeric O-antigen of the lipopolysaccharide from Pseudomonas aeruginosa serogroup O5 as well as the band-A trisaccharide from Bordetella pertussis contain the di-N-acetylated...

Predicting Protein Function from Structure—The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis

King, Jerry D., Harmer, Nicholas J., Preston, Andrew, Palmer, Colin M., Rejzek, Martin, Field, Robert A., ...

The pathogenic bacteria Bordetella parapertussis and Bordetella bronchiseptica express a lipopolysaccharide O antigen containing a polymer of 2,3-diacetamido-2,3-dideoxy-l-galacturonic acid. The...