A target site for template-based design of measles virus entry inhibitors
Plemper, Richard K., Erlandson, Karl J., Lakdawala, Ami S., Sun, Aiming, Prussia, Andrew, Boonsombat, Jutatip, ...
Measles virus (MV) constitutes a principal cause of worldwide mortality, accounting for almost 1 million deaths annually. Although a live-attenuated vaccine protects against MV, vaccination...
Design of a Small-Molecule Entry Inhibitor with Activity against Primary Measles Virus Strains
Plemper, Richard K., Doyle, Joshua, Sun, Aiming, Prussia, Andrew, Cheng, Li-Ting, Rota, Paul A., ...
The incidence of measles virus (MV) infection has been significantly reduced in many nations through extensive vaccination; however, the virus still causes significant morbidity and mortality in...
Doyle, Joshua, Prussia, Andrew, White, Laura K., Sun, Aiming, Liotta, Dennis C., Snyder, James P., ...
Most viral glycoproteins mediating membrane fusion adopt a metastable native conformation and undergo major conformational changes during fusion. We previously described a panel of compounds that...
A target site for template-based design of measles virus entry inhibitors
Plemper, Richard K., Erlandson, Karl J., Lakdawala, Ami S., Sun, Aiming, Prussia, Andrew, Boonsombat, Jutatip, ...
Measles virus (MV) constitutes a principal cause of worldwide mortality, accounting for almost 1 million deaths annually. Although a live-attenuated vaccine protects against MV, vaccination...
Design of a Small-Molecule Entry Inhibitor with Activity against Primary Measles Virus Strains
Plemper, Richard K., Doyle, Joshua, Sun, Aiming, Prussia, Andrew, Cheng, Li-Ting, Rota, Paul A., ...
The incidence of measles virus (MV) infection has been significantly reduced in many nations through extensive vaccination; however, the virus still causes significant morbidity and mortality in...
Doyle, Joshua, Prussia, Andrew, White, Laura K., Sun, Aiming, Liotta, Dennis C., Snyder, James P., ...
Most viral glycoproteins mediating membrane fusion adopt a metastable native conformation and undergo major conformational changes during fusion. We previously described a panel of compounds that...
Lee, Jin K., Prussia, Andrew, Snyder, James P., Plemper, Richard K.
In search of target sites for the development of paramyxovirus inhibitors, we have engineered disulfide bridges to introduce covalent links into the prefusion F protein trimer of measles virus....
Regulation of Bestrophin Cl Channels by Calcium: Role of the C Terminus
Xiao, Qinghuan, Prussia, Andrew, Yu, Kuai, Cui, Yuan-yuan, Hartzell, H. Criss
Human bestrophin-1 (hBest1), which is genetically linked to several kinds of retinopathy and macular degeneration in both humans and dogs, is the founding member of a family of Cl− ion channels...
Functional Interaction between Paramyxovirus Fusion and Attachment Proteins*S⃞
Lee, Jin K., Prussia, Andrew, Paal, Tanja, White, Laura K., Snyder, James P., Plemper, Richard K.
Paramyxovirinae envelope glycoproteins constitute a premier model to dissect how specific and dynamic interactions in multisubunit membrane protein complexes can control deep-seated conformational...