Andrew Wilkins

The Dictyosteliumgenome encodes numerous RasGEFs with multiple biological roles (2005)

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

Abstract Background Dictyostelium discoideum is a eukaryote with a simple lifestyle and a relatively small genome whose sequence has been fully determined. It is widely used for studies on cell...

RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex (2004)

Wilkins, Andrew, Ping, Qinggong, Carpenter, Christopher L.

Rhobtb2 is a candidate tumor suppressor located on human chromosome 8p21, a region commonly deleted in cancer. Rhobtb2 is homozygously deleted in 3.5% of primary breast cancers, and gene expression...

Dictyostelium RasD is required for normal phototaxis, but not differentiation

Wilkins, Andrew, Khosla, Meenal, Fraser, Derek J., Spiegelman, George B., Fisher, Paul R., Weeks, Gerald, ...

RasD, a Dictyostelium homolog of mammalian Ras, is maximally expressed during the multicellular stage of development. Normal Dictyostelium aggregates are phototactic and thermotactic, moving towards...

RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex

Wilkins, Andrew, Ping, Qinggong, Carpenter, Christopher L.

Rhobtb2 is a candidate tumor suppressor located on human chromosome 8p21, a region commonly deleted in cancer. Rhobtb2 is homozygously deleted in 3.5% of primary breast cancers, and gene expression...

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

A survey of the Dictyostelium genome reveals at least 25 RasGEFs, all of which appear to be expressed at some point in development. Disruption of several of these novel RasGEFs reveals that many have...

Dictyostelium RasD is required for normal phototaxis, but not differentiation

Wilkins, Andrew, Khosla, Meenal, Fraser, Derek J., Spiegelman, George B., Fisher, Paul R., Weeks, Gerald, ...

RasD, a Dictyostelium homolog of mammalian Ras, is maximally expressed during the multicellular stage of development. Normal Dictyostelium aggregates are phototactic and thermotactic, moving towards...

RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex

Wilkins, Andrew, Ping, Qinggong, Carpenter, Christopher L.

Rhobtb2 is a candidate tumor suppressor located on human chromosome 8p21, a region commonly deleted in cancer. Rhobtb2 is homozygously deleted in 3.5% of primary breast cancers, and gene expression...

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles

Wilkins, Andrew, Szafranski, Karol, Fraser, Derek J, Bakthavatsalam, Deenadayalan, Müller, Rolf, Fisher, Paul R, ...

A survey of the Dictyostelium genome reveals at least 25 RasGEFs, all of which appear to be expressed at some point in development. Disruption of several of these novel RasGEFs reveals that many have...