Angela van Daal

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans (2008)

Voisey, Joanne, Swagell, Christopher D., Hughes, Ian P., Morris, C. Phillip, Van Daal, Angela, Noble, Earnest P., ...

Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic...

Unravelling the molecular control of calvarial suture fusion in children with craniosynostosis (2007)

Coussens, Anna K, Wilkinson, Christopher R, Hughes, Ian P, Morris, C Phillip, Van Daal, Angela, Anderson, Peter J, ...

Abstract Background Craniosynostosis, the premature fusion of calvarial sutures, is a common craniofacial abnormality. Causative mutations in more than 10 genes have been identified, involving...

A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA (2006)

Voisey, Joanne, Smit, D. J., Leonard, J. Helen, Sturm, Rick A., Van Daal, Angela

To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin...

A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA (2006)

Voisey, Joanne, Smit, D. J., Leonard, J. Helen, Sturm, Rick A., Van Daal, Angela

To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin...

Association of functionally different RUNX2 P2 promoter alleles with BMD (2006)

Doecke, James D, Day, Christopher J, Stephens, Alexandre S, Carter, Shea L, Van Daal, Angela, Kotowicz, Mark A, ...

RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age- and weight-adjusted femoral neck BMD. Of 16 SNPs in RUNX2 and its two promoters (P1 and P2), only SNPs in the P2...

Association of functionally different RUNX2 P2 promoter alleles with BMD (2006)

Doecke, James D, Day, Christopher J, Stephens, Alexandre SJ, Carter, Shea L, Van Daal, Angela, Kotowicz, Mark A, ...

RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age- and weight-adjusted femoral neck BMD. Of 16 SNPs in RUNX2 and its two promoters (P1 and P2), only SNPs in the P2...

Association of functionally different RUNX2 P2 promoter alleles with BMD (2006)

Doecke, James D, Day, Christopher J, Stephens, Alexandre SJ, Carter, Shea L, Van Daal, Angela, Kotowicz, Mark A, ...

RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age- and weight-adjusted femoral neck BMD. Of 16 SNPs in RUNX2 and its two promoters (P1 and P2), only SNPs in the P2...

A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA (2006)

Voisey, Joanne, Smit, D. J., Leonard, J. Helen, Sturm, Rick A., Van Daal, Angela

To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin...

Association of functionally different RUNX2 P2 promoter alleles with BMD (2006)

Doecke, James D, Day, Christopher J, Stephens, Alexandre SJ, Carter, Shea L, Van Daal, Angela, Kotowicz, Mark A, ...

RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age- and weight-adjusted femoral neck BMD. Of 16 SNPs in RUNX2 and its two promoters (P1 and P2), only SNPs in the P2...

A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA (2006)

Voisey, Joanne, Smit, D. J., Leonard, J. Helen, Sturm, Rick A., Van Daal, Angela

To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin...

Association of functionally different RUNX2 P2 promoter alleles with BMD (2006)

Doecke, James D, Day, Christopher J, Stephens, Alexandre SJ, Carter, Shea L, Van Daal, Angela, Kotowicz, Mark A, ...

RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age- and weight-adjusted femoral neck BMD. Of 16 SNPs in RUNX2 and its two promoters (P1 and P2), only SNPs in the P2...

Gene polymorphisms and their effects in the melanocortin system (2005)

Carroll, Levi, Voisey, Joanne, Van Daal, Angela

In addition to its role in human pigmentation, components of the melanocortin system regulate appetite, energy homeostasis and hormone production. Recent studies have suggested possible roles of this...

Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation (2005)

Graf, Justin, Hodgson, Richard, Van Daal, Angela

Human physical pigmentation is determined by the type and amount of melanin and the process of pigmentation production probably involves more than 100 genes. A failure to synthesize melanin results...

Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation (2005)

Graf, Justin, Hodgson, Richard, Van Daal, Angela

Human physical pigmentation is determined by the type and amount of melanin and the process of pigmentation production probably involves more than 100 genes. A failure to synthesize melanin results...

Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape (2005)

Van Daal, Angela, Coussens, Anna K.

Mutations in FGFR1 and TWIST1 have been reported to affect the timing of calvarial suture fusion resulting in craniosynostosis and facial abnormalities. We screened nonpathologic populations for...

Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape (2005)

Van Daal, Angela, Coussens, Anna K.

Mutations in FGFR1 and TWIST1 have been reported to affect the timing of calvarial suture fusion resulting in craniosynostosis and facial abnormalities. We screened nonpathologic populations for...

The C/C genotype of the C957T polymorphism of the dopamine D2 receptor (DRD2) is associated with schizophrenia (2005)

Lawford, Bruce R, Young, Ross McD, Swagell, Christopher D, Barnes, Mark, Burton, Simon C, Ward, Warren K, ...

The T allele of the human dopamine D2 receptor (DRD2) gene C957T polymorphism is associated with reduced mRNA translation and stability. This results in decreased dopamine induced DRD2 upregulation...

The C/C genotype of the C957T polymorphism of the dopamine D2 receptor (DRD2) is associated with schizophrenia (2005)

Lawford, Bruce R, Young, Ross McD, Swagell, Christopher D, Barnes, Mark, Burton, Simon C, Ward, Warren K, ...

The T allele of the human dopamine D2 receptor (DRD2) gene C957T polymorphism is associated with reduced mRNA translation and stability. This results in decreased dopamine induced DRD2 upregulation...

Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation (2005)

Graf, Justin, Hodgson, Richard, Van Daal, Angela

Human physical pigmentation is determined by the type and amount of melanin and the process of pigmentation production probably involves more than 100 genes. A failure to synthesize melanin results...

Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape (2005)

Van Daal, Angela, Coussens, Anna K.

Mutations in FGFR1 and TWIST1 have been reported to affect the timing of calvarial suture fusion resulting in craniosynostosis and facial abnormalities. We screened nonpathologic populations for...

The C/C genotype of the C957T polymorphism of the dopamine D2 receptor (DRD2) is associated with schizophrenia (2005)

Lawford, Bruce R, Young, Ross McD, Swagell, Christopher D, Barnes, Mark, Burton, Simon C, Ward, Warren K, ...

The T allele of the human dopamine D2 receptor (DRD2) gene C957T polymorphism is associated with reduced mRNA translation and stability. This results in decreased dopamine induced DRD2 upregulation...

Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation (2005)

Graf, Justin, Hodgson, Richard, Van Daal, Angela

Human physical pigmentation is determined by the type and amount of melanin and the process of pigmentation production probably involves more than 100 genes. A failure to synthesize melanin results...

Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape (2005)

Van Daal, Angela, Coussens, Anna K.

Mutations in FGFR1 and TWIST1 have been reported to affect the timing of calvarial suture fusion resulting in craniosynostosis and facial abnormalities. We screened nonpathologic populations for...

The C/C genotype of the C957T polymorphism of the dopamine D2 receptor (DRD2) is associated with schizophrenia (2005)

Lawford, Bruce R, Young, Ross McD, Swagell, Christopher D, Barnes, Mark, Burton, Simon C, Ward, Warren K, ...

The T allele of the human dopamine D2 receptor (DRD2) gene C957T polymorphism is associated with reduced mRNA translation and stability. This results in decreased dopamine induced DRD2 upregulation...

Mouse models of obesity (2004)

Levi, Carroll, Voisey, Joanne, Van Daal, Angela

Insights into the etiology of human obesity have arisen from the study of animal models. Animal models of obesity are also important for the development of future treatments of obesity. An agouti...

Mouse models of obesity (2004)

Levi, Carroll, Voisey, Joanne, Van Daal, Angela

Insights into the etiology of human obesity have arisen from the study of animal models. Animal models of obesity are also important for the development of future treatments of obesity. An agouti...

Mouse models of obesity (2004)

Levi, Carroll, Voisey, Joanne, Van Daal, Angela

Insights into the etiology of human obesity have arisen from the study of animal models. Animal models of obesity are also important for the development of future treatments of obesity. An agouti...

Mouse models of obesity (2004)

Levi, Carroll, Voisey, Joanne, Van Daal, Angela

Insights into the etiology of human obesity have arisen from the study of animal models. Animal models of obesity are also important for the development of future treatments of obesity. An agouti...

Agouti signal protein regulation in human melanoma cells (2003)

Voisey, Joanne, Kelly, Greg, Van Daal, Angela

Production of the pigment eumelanin is controlled by α-melanocyte stimulating hormone (α-MSH) stimulation of melanocortin 1 receptor (Mc1r), whereas production of pheomelanin results from agouti...

Agouti signal protein regulation in human melanoma cells (2003)

Voisey, Joanne, Kelly, Greg, Van Daal, Angela

Production of the pigment eumelanin is controlled by α-melanocyte stimulating hormone (α-MSH) stimulation of melanocortin 1 receptor (Mc1r), whereas production of pheomelanin results from agouti...

Agouti signal protein regulation in human melanoma cells (2003)

Voisey, Joanne, Kelly, Greg, Van Daal, Angela

Production of the pigment eumelanin is controlled by α-melanocyte stimulating hormone (α-MSH) stimulation of melanocortin 1 receptor (Mc1r), whereas production of pheomelanin results from agouti...

Agouti signal protein regulation in human melanoma cells (2003)

Voisey, Joanne, Kelly, Greg, Van Daal, Angela

Production of the pigment eumelanin is controlled by α-melanocyte stimulating hormone (α-MSH) stimulation of melanocortin 1 receptor (Mc1r), whereas production of pheomelanin results from agouti...

Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific (2002)

Voisey, Joanne, Imbeault, Pascal, Hutley, Louise, Prins, John B, Van Daal, Angela

OBJECTIVE: To determine if human adipocyte agouti signal protein (ASIP) mRNA expression is associated with obesity and is gender and/or depot specific. RESEARCH METHODS AND PROCEDURES: Subjects...

Agouti: From mouse to man, from skin to fat (2002)

Voisey, Joanne, Van Daal, Angela

The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its effect on pigmentation is achieved by antagonizing the binding of...

Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific (2002)

Voisey, Joanne, Imbeault, Pascal, Hutley, Louise, Prins, John B, Van Daal, Angela

OBJECTIVE: To determine if human adipocyte agouti signal protein (ASIP) mRNA expression is associated with obesity and is gender and/or depot specific. RESEARCH METHODS AND PROCEDURES: Subjects...

Agouti: From mouse to man, from skin to fat (2002)

Voisey, Joanne, Van Daal, Angela

The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its effect on pigmentation is achieved by antagonizing the binding of...

Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific (2002)

Voisey, Joanne, Imbeault, Pascal, Hutley, Louise, Prins, John B, Van Daal, Angela

OBJECTIVE: To determine if human adipocyte agouti signal protein (ASIP) mRNA expression is associated with obesity and is gender and/or depot specific. RESEARCH METHODS AND PROCEDURES: Subjects...

Agouti: From mouse to man, from skin to fat (2002)

Voisey, Joanne, Van Daal, Angela

The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its effect on pigmentation is achieved by antagonizing the binding of...

Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific (2002)

Voisey, Joanne, Imbeault, Pascal, Hutley, Louise, Prins, John B, Van Daal, Angela

OBJECTIVE: To determine if human adipocyte agouti signal protein (ASIP) mRNA expression is associated with obesity and is gender and/or depot specific. RESEARCH METHODS AND PROCEDURES: Subjects...

Agouti: From mouse to man, from skin to fat (2002)

Voisey, Joanne, Van Daal, Angela

The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its effect on pigmentation is achieved by antagonizing the binding of...

A polymorphism study of the human agouti gene and its association with MC1R (2001)

Voisey, Joanne, Box, Neil, Van Daal, Angela

To determine whether the Agouti Signalling Protein (ASP) gene is associated with skin and hair coloration in humans, the complete coding region of ASP was screened for polymorphisms. Analysis of ASP...

Solid-phase amplification and detection: A single-tube diagnostic assay for infectious agents (2001)

Somodevilla-Torres , Maria, Timms, Peter, Harris , Ray, Morris, Phillip, Van Daal , Angela

BACKGROUND: We report the development of an enzyme-linked immunosorbent assay[mdash ]like single-tube assay for the detection of infectious agents in a microtiter tray format. METHODS AND RESULTS:...

A polymorphism study of the human agouti gene and its association with MC1R (2001)

Voisey, Joanne, Box, Neil, Van Daal, Angela

To determine whether the Agouti Signalling Protein (ASP) gene is associated with skin and hair coloration in humans, the complete coding region of ASP was screened for polymorphisms. Analysis of ASP...

Solid-phase amplification and detection: A single-tube diagnostic assay for infectious agents (2001)

Somodevilla-Torres , Maria, Timms, Peter, Harris , Ray, Morris, Phillip, Van Daal , Angela

BACKGROUND: We report the development of an enzyme-linked immunosorbent assay[mdash ]like single-tube assay for the detection of infectious agents in a microtiter tray format. METHODS AND RESULTS:...

A polymorphism study of the human agouti gene and its association with MC1R (2001)

Voisey, Joanne, Box, Neil, Van Daal, Angela

To determine whether the Agouti Signalling Protein (ASP) gene is associated with skin and hair coloration in humans, the complete coding region of ASP was screened for polymorphisms. Analysis of ASP...

Solid-phase amplification and detection: A single-tube diagnostic assay for infectious agents (2001)

Somodevilla-Torres , Maria, Timms, Peter, Harris , Ray, Morris, Phillip, Van Daal , Angela

BACKGROUND: We report the development of an enzyme-linked immunosorbent assay[mdash ]like single-tube assay for the detection of infectious agents in a microtiter tray format. METHODS AND RESULTS:...

A polymorphism study of the human agouti gene and its association with MC1R (2001)

Voisey, Joanne, Box, Neil, Van Daal, Angela

To determine whether the Agouti Signalling Protein (ASP) gene is associated with skin and hair coloration in humans, the complete coding region of ASP was screened for polymorphisms. Analysis of ASP...

Solid-phase amplification and detection: A single-tube diagnostic assay for infectious agents (2001)

Somodevilla-Torres , Maria, Timms, Peter, Harris , Ray, Morris, Phillip, Van Daal , Angela

BACKGROUND: We report the development of an enzyme-linked immunosorbent assay[mdash ]like single-tube assay for the detection of infectious agents in a microtiter tray format. METHODS AND RESULTS:...

Drosophila has a single copy of the gene encoding a highly conserved histone H2A variant of the H2A. F/Z type (1988)

Van Daal, Angela, White, Elizabeth M., Gorovsky, Martin A., Elgin, C.R.

The Tetrahymena histone H2A variant designated hv1 is localized exclusively in the transcriptionally active macronuclous and is absent from the quiescent micronucleus (1) . A cDNA clone of tha hv1...

Identification and Minisequencing-Based Discrimination of SHV β-Lactamases in Nosocomial Infection-Associated Klebsiella pneumoniae in Brisbane, Australia

Howard, Christopher, Van Daal, Angela, Kelly, Gregory, Schooneveldt, Jacqueline, Nimmo, Graeme, Giffard, Philip M.

Extended-spectrum β-lactamases (ESBLs) are active against oxyimino cephalosporins and monobactams. Twenty-one Klebsiella pneumoniae isolates obtained between 1991 and 1995 at the Princess Alexandra...

Validity of Low Copy Number Typing and Applications to Forensic Science

Budowle, Bruce, Eisenberg, Arthur J., Van Daal, Angela

Low copy number (LCN) typing, particularly for current short tandem repeat (STR) typing, refers to the analysis of any sample that contains less than 200 pg of template DNA. Generally, LCN typing...