Ann E. Wakefield

Determination of the Copy Number of the Nuclear rDNA and Beta-tubulin Genes of Pneumocystis carinii f. sp. hominis Using PCR Multicompetitors (2000)

Aimable Nahimana, Patrick Francioli, Dominique S. Blanc, J. Bille, Ann E. Wakefield, Philippe M. SHauser

Multiple copies of a gene may lead to difficulty in the interpretation of typing results because polymorphism of the copies may wrongly lead to the conclusion that different types are present in a...

Phylogeny of Pneumocystis carinii from 18 Primate Species Confirms Host Specificity and Suggests Coevolution

Demanche, Christine, Berthelemy, Madeleine, Petit, Thierry, Polack, Bruno, Wakefield, Ann E., Dei-Cas, Eduardo, ...

Primates are regularly infected by fungal organisms identified as Pneumocystis carinii. They constitute a valuable population for the confirmation of P. carinii host specificity. In this study, the...

Pneumocystis carinii f. sp. hominis DNA in Immunocompetent Health Care Workers in Contact with Patients with P. carinii Pneumonia

Miller, Robert F., Ambrose, Helen E., Wakefield, Ann E.

The possible transmission of Pneumocystis carinii f. sp. hominis from patients with P. carinii pneumonia to asymptomatic health care workers (HCW), with or without occupational exposure to human...

Population Structure of Rat-Derived Pneumocystis carinii in Danish Wild Rats

Palmer, Robert J., Settnes, Osvald P., Lodal, Jens, Wakefield, Ann E.

The rat model of Pneumocystis carinii pneumonia is frequently used to study human P. carinii infection, but there are many differences between the rat and human infections. We studied naturally...

Pre-AIDS Era Isolates of Pneumocystis carinii f. sp. hominis: High Genotypic Similarity with Contemporary Isolates

Tsolaki, Anthony G., Beckers, Pieter, Wakefield, Ann E.

Isolates of Pneumocystis carinii f. sp. hominis were examined from six individuals who died of P. carinii pneumonia between 1968 and 1981 and who had underlying immunodeficiencies which were not due...

Probable Mother-to-Infant Transmission of Pneumocystis carinii f. sp. hominis Infection

Miller, Robert F., Ambrose, Helen E., Novelli, Vas, Wakefield, Ann E.

A mother and her 4.5-week-old infant had Pneumocystis carinii pneumonia contemporaneously. Genotyping of P. carinii f. sp. hominis DNA at three independent loci showed the same genotype in samples...

Genotypes of Pneumocystis jiroveci Isolates Obtained in Harare, Zimbabwe, and London, United Kingdom

Miller, Robert F., Lindley, Austin R., Ambrose, Helen E., Malin, Adam S., Wakefield, Ann E.

Isolates of Pneumocystis jiroveci from sulfa-exposed and nonexposed patients from London, United Kingdom, and Harare, Zimbabwe, were genotyped. At the dihydropteroate synthase (DHPS) locus, there was...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...

Phylogeny of Pneumocystis carinii from 18 Primate Species Confirms Host Specificity and Suggests Coevolution

Demanche, Christine, Berthelemy, Madeleine, Petit, Thierry, Polack, Bruno, Wakefield, Ann E., Dei-Cas, Eduardo, ...

Primates are regularly infected by fungal organisms identified as Pneumocystis carinii. They constitute a valuable population for the confirmation of P. carinii host specificity. In this study, the...

Pneumocystis carinii f. sp. hominis DNA in Immunocompetent Health Care Workers in Contact with Patients with P. carinii Pneumonia

Miller, Robert F., Ambrose, Helen E., Wakefield, Ann E.

The possible transmission of Pneumocystis carinii f. sp. hominis from patients with P. carinii pneumonia to asymptomatic health care workers (HCW), with or without occupational exposure to human...

Population Structure of Rat-Derived Pneumocystis carinii in Danish Wild Rats

Palmer, Robert J., Settnes, Osvald P., Lodal, Jens, Wakefield, Ann E.

The rat model of Pneumocystis carinii pneumonia is frequently used to study human P. carinii infection, but there are many differences between the rat and human infections. We studied naturally...

Pre-AIDS Era Isolates of Pneumocystis carinii f. sp. hominis: High Genotypic Similarity with Contemporary Isolates

Tsolaki, Anthony G., Beckers, Pieter, Wakefield, Ann E.

Isolates of Pneumocystis carinii f. sp. hominis were examined from six individuals who died of P. carinii pneumonia between 1968 and 1981 and who had underlying immunodeficiencies which were not due...

Probable Mother-to-Infant Transmission of Pneumocystis carinii f. sp. hominis Infection

Miller, Robert F., Ambrose, Helen E., Novelli, Vas, Wakefield, Ann E.

A mother and her 4.5-week-old infant had Pneumocystis carinii pneumonia contemporaneously. Genotyping of P. carinii f. sp. hominis DNA at three independent loci showed the same genotype in samples...

Genotypes of Pneumocystis jiroveci Isolates Obtained in Harare, Zimbabwe, and London, United Kingdom

Miller, Robert F., Lindley, Austin R., Ambrose, Helen E., Malin, Adam S., Wakefield, Ann E.

Isolates of Pneumocystis jiroveci from sulfa-exposed and nonexposed patients from London, United Kingdom, and Harare, Zimbabwe, were genotyped. At the dihydropteroate synthase (DHPS) locus, there was...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...