Xiaorong Lin, Anastasia P. Litvintseva, Kirsten Nielsen, Sweta Patel, Anna Floyd, Thomas G. Mitchell, ...
Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically haploid, and sexual reproduction...
'PACLIMS': A component LIM system for high-throughput functional genomic analysis (2005)
Donofrio, Nicole, Rajagopalon, Ravi, Brown, Douglas, Diener, Stephen, Windham, Donald, Nolin, Shelly, ...
Abstract Background Recent advances in sequencing techniques leading to cost reduction have resulted in the generation of a growing number of sequenced eukaryotic genomes. Computational tools greatly...
'PACLIMS': A component LIM system for high-throughput functional genomic analysis
Donofrio, Nicole, Rajagopalon, Ravi, Brown, Douglas, Diener, Stephen, Windham, Donald, Nolin, Shelly, ...
'PACLIMS': A component LIM system for high-throughput functional genomic analysis
Donofrio, Nicole, Rajagopalon, Ravi, Brown, Douglas, Diener, Stephen, Windham, Donald, Nolin, Shelly, ...
αADα Hybrids of Cryptococcus neoformans: Evidence of Same-Sex Mating in Nature and Hybrid Fitness
Lin, Xiaorong, Litvintseva, Anastasia P, Nielsen, Kirsten, Patel, Sweta, Floyd, Anna, Mitchell, Thomas G, ...
Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically haploid, and sexual reproduction...
Lin, Xiaorong, Patel, Sweta, Litvintseva, Anastasia P., Floyd, Anna, Mitchell, Thomas G., Heitman, Joseph
The ubiquitous environmental human pathogen Cryptococcus neoformans is traditionally considered a haploid fungus with a bipolar mating system. In nature, the α mating type is overwhelmingly...
Idnurm, Alexander, Walton, Felicia J., Floyd, Anna, Reedy, Jennifer L., Heitman, Joseph
A library of more than 4,500 signature-tagged insertion mutants of the human pathogenic fungus Cryptococcus neoformans was generated, and a subset was screened in a murine inhalation model to...