Reply: Potential conflict of interest: Nothing to report. (2006)
Lok, Anna Suk-Fong, Lok, Anna Suk-Fong
No abstract.
Yim, Hyung Joon, Lok, Anna Suk-Fong
Remarkable progress has been made in our understanding of the natural history of chronic hepatitis B virus (HBV) infection in the past 25 years. Availability of sensitive HBV DNA assays and...
Reply: Potential conflict of interest: Nothing to report. (2005)
Marrero, Jorge A., Fontana, Robert J., Su, Grace L., Conjeevaram, Hari S., Lok, Anna Suk-Fong, Marrero, Jorge A., ...
No abstract.
Lok, Anna Suk-Fong, Ghany, Marc G., Goodman, Zachary D., Wright, Elizabeth C., Everson, Gregory T., Sterling, Richard K., ...
Knowledge of the presence of cirrhosis is important for the management of patients with chronic hepatitis C (CHC). Most models for predicting cirrhosis were derived from small numbers of patients and...
No abstract.
Marrero, Jorge A., Fontana, Robert J., Barrat, Ashley, Askari, Frederick K., Conjeevaram, Hari S., Su, Grace L., ...
Currently there is no consensus as to which staging system is best in predicting the survival of patients with hepatocellular carcinoma (HCC). The aims of this study were to identify independent...
Marrero, Jorge A., Hussain, Hero K., Nghiem, Hahn V., Umar, Ramsey, Fontana, Robert J., Lok, Anna Suk-Fong
In the United States, cirrhotic patients with known or suspected hepatocellular carcinoma (HCC) are prioritized for liver transplantation. Noninvasive criteria for the diagnosis of HCC rely on...
Reply Conflict of interest: Nothing to report. (2005)
Lok, Anna Suk-Fong, Lok, Anna Suk-Fong
No abstract.
Fung, Scott K., Lok, Anna Suk-Fong
No abstract.
Hepatitis B virus genotypes: Do they play a role in the outcome of HBV infection? (2004)
Fung, Scott K., Lok, Anna Suk-Fong
No Abstract.
Lok, Anna Suk-Fong, McMahon, Brian J.
No abstract.
Prevalence of HBV precore/core promoter variants in the United States (2003)
Chu, Chi-Jen, Keeffe, Emmet B., Han, Steven-Huy, Perrillo, Robert P., Min, Albert D., Soldevila-Pico, Consuelo, ...
Variants in the precore (G 1896 A) and core promoter (A 1762 T, G 1764 A) regions of hepatitis B virus (HBV) may be related to serum HBV DNA levels and severity of liver disease. The aims of this...
Wai, Chun-Tao, Greenson, Joel K., Fontana, Robert J., Kalbfleisch, John D., Marrero, Jorge A., Conjeevaram, Hari S., ...
Information on the stage of liver fibrosis is essential in managing chronic hepatitis C (CHC) patients. However, most models for predicting liver fibrosis are complicated and separate formulas are...
The Role of Optimism/Pessimism in HRQOL in Chronic Hepatitis C Patients (2003)
Moyer, Cheryl A., Fontana, Robert J., Hussain, Khozema, Lok, Anna Suk-Fong, Schwartz, Steven M.
One hundred and twenty three outpatients with compensated chronic hepatitis C (CHC) completed the SF-36, BSI, and questions regarding the expected impact of CHC on their health. Respondents were...
Marrero, Jorge A., Fontana, Robert J., Su, Grace L., Conjeevaram, Hari S., Emick, Dawn M., Lok, Anna Suk-Fong
The incidence of hepatocellular carcinoma (HCC) in the United States is increasing, but the clinical characteristics of American patients with HCC have not been well described. The aims of this study...
Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection (2002)
Chu, Chi-Jen, Hussain, Munira, Lok, Anna Suk-Fong
The goals of this retrospective study were to determine whether there is a threshold hepatitis B virus (HBV) DNA value associated with spontaneous or antiviral therapy—related hepatitis B e antigen...
Wai, Chun-Tao, Chu, Chi-Jen, Hussain, Munira, Lok, Anna Suk-Fong
Hepatitis B virus (HBV) genotype and precore/core promoter mutations have been implicated in spontaneous and interferon alfa (IFN-Α)—related hepatitis B e antigen (HBeAg) seroconversion. We...
Noninvasive monitoring of patients with chronic hepatitis C (2002)
Fontana, Robert J., Lok, Anna Suk-Fong
Hepatic fibrosis is the main determinant of clinical outcomes of chronic hepatitis C. Liver histology is frequently considered the gold standard for assessing hepatic fibrosis. However, liver biopsy...
Combination of HBIG and lamivudine-resistant mutations: A formula for trouble? (2002)
Fontana, Robert J., Lok, Anna Suk-Fong
Background & Aims: Lamivudine has become a main therapeutic option for treating hepatitis B virus (HBV) infection. Although drug resistance develops, the clinical course after selection of...
Prevention of recurrent hepatitis B post–liver transplantation (2002)
1 Factors associated with a lower rate of recurrent hepatitis B post–liver transplantation (LT) are negative hepatitis B e antigen and/or serum hepatitis B virus DNA pre-LT, hepatitis D virus...
Treatment of hepatitis B (2002)
Lok, Anna Suk-Fong, Wai, Chun-Tao
Chronic hepatitis B virus (HBV) infection affects approximately 350 million people worldwide. Treatment of chronic hepatitis B is aimed at sustained suppression of HBV replication and remission of...
Clinical significance of hepatitis B virus genotypes (2002)
Chu, Chi-Jen, Lok, Anna Suk-Fong
No Abstract.
Fontana, Robert J., Keeffe, Emmet B., Carey, William, Fried, Michael, Reddy, Rajender K., Kowdley, Kris V., ...
The primary aim of this study is to determine whether treatment with lamivudine improved pre–liver transplantation (pre-LT) and LT-free survival of patients awaiting LT for hepatitis B virus...
Outcome of liver transplantation for hepatitis B: Report of a single center's experience (2001)
Chu, Chi-Jen, Fontana, Robert J., Moore, Charles, Armstrong, Douglas R., Punch, Jeffrey D., Su, Grace L., ...
Results of liver transplantation (LT) for hepatitis B have improved significantly with the use of hepatitis B immune globulin (HBIG) and/or lamivudine. The aim of this study is to review the...
Teo, Eng-Kiong, Han, Steven-Huy, Terrault, Norah, Luketic, Velimir A., Jensen, Donald, Keeffe, Emmet B., ...
Previous studies have found that Asian patients transplanted for hepatitis B virus (HBV) infection had worse outcomes than white patients. The aim of this study was to compare outcomes in Asian and...
Occult hepatitis B virus infection: A hidden menace? (2001)
Conjeevaram, Hari S., Lok, Anna Suk-Fong
No Abstract.
Hepatitis B infection in patients with acute liver failure in the United States (2001)
Teo, Eng-Kiong, Ostapowicz, George, Hussain, Munira, Lee, William M., Fontana, Robert J., Lok, Anna Suk-Fong
Occult hepatitis B virus (HBV) infection has been reported in 30% to 50% of patients with acute liver failure (ALF) in small case series. The aim of this study was to determine the prevalence of...
Lok, Anna Suk-Fong, Hussain, Munira, Cursano, Carmela, Margotti, Marzia, Gramenzi, Annagiulia, Luca Grazi, Gian, ...
Lamivudine has been shown to be effective in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B, but its long-term efficacy and the rate of resistant mutations in patients with...
Chu, Chi-Jen, Lok, Anna Suk-Fong
No Abstract.
Hepatitis B e antigen–negative chronic hepatitis b in Hong Kong (2000)
Chan, Henry L. Y., Leung, Nancy W. Y., Hussain, Munira, Wong, May L., Lok, Anna Suk-Fong
Hepatitis B e antigen–negative chronic hepatitis B (e−CHB) has been reported in Asia but its prevalence and clinical significance have not been determined. The aims of this study were to...
Shehab, Thomas M., Sonnad, Seema S., Jeffries, Mark A., Gunaratnum, Naresh, Lok, Anna Suk-Fong
Approximately 4 million Americans are infected with the hepatitis C virus (HCV). Most patients with hepatitis C have no symptoms until cirrhosis is established. Thus, initial diagnosis and management...
Chan, Henry L. Y., Hussain, Munira, Lok, Anna Suk-Fong
Mutations in the core promoter and precore regions are frequently found in hepatitis B e antigen (HBeAg)-negative patients, but precore stop codon mutation is restricted to hepatitis B virus (HBV)...
Ghany, Marc G., Ayola, Brick, Villamil, Federico G., Gish, Robert G., Rojter, Sergio, Vierling, John M., ...
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. The aim of this study was to determine the...
Diagnosis of hepatitis C (1997)
Lok, Anna Suk-Fong, Gunaratnam, N T
Currently, the second- and third-generation enzyme immunoassays (EIA-2 and EIA-3) for hepatitis C virus antibody (anti-HCV) are the most practical screening tests for the diagnosis of HCV infection....
HEPATITIS B VIRUS INFECTION IN CHINESE FAMILIES IN HONGKONG (1987)
LOK, ANNA SUK-FONG, LAI, CHING-LUNG, WU, PUI-CHEE, WONG, VIVIAN CHIWOON, YEOH, ENG-KIANG, LIN, HSIANG-JU
Lok, A. S-F. (U. Dept. of Medicine, Queen Mary Hospital, Hong Kong), C-L. Lai, P-C. Wu, V. C-W. Wong, E-K. Yeoh, and H-J. Lin. Hepatitis B virus infection in Chinese families in Hong Kong. Am J...
Ito, Kiyoaki, Kim, Kyun-Hwan, Lok, Anna Suk-Fong, Tong, Shuping
Hepatitis B e antigen (HBeAg) is a secreted version of hepatitis B virus (HBV) core protein that promotes immune tolerance and persistent infection. It is derived from a translation product of the...