Anne Van Hecken

The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers (2007)

Van Hecken, Anne; U0011994, De Lepeleire, I, Thach, C, Oeyen, M, Van Effen, J, ...

INTRODUCTION: Nasal congestion in allergic rhinitis results from tissue edema and vasodilatation in the nasal mucosa. Of the mediators released by mast cells in response to allergens, prostaglandin...

Pharmacodynamics and pharmacokinetics of RWJ-53308, a nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist, in healthy men (1998)

Van Hecken, Anne; U0011994, Wynants, K, Arnout, Jozef; U0003986, Doose, D, Abels, R, ...

[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

Burns, H. Donald, Van Laere, Koen, Sanabria-Bohórquez, Sandra, Hamill, Terence G., Bormans, Guy, Eng, Wai-si, ...

[18F]MK-9470 is a selective, high-affinity, inverse agonist (human IC50, 0.7 nM) for the cannabinoid CB1 receptor (CB1R) that has been developed for use in human brain imaging. Autoradiographic...