Malchow, Dieter, Lusche, Daniel F, Schlatterer, Christina, De Lozanne, Arturo, Müller-Taubenberger, Annette
Abstract Background cAMP-induced Ca 2+ -influx in Dictyostelium is controlled by at least two non-mitochondrial Ca 2+ -stores: acidic stores and the endoplasmic reticulum (ER). The acidic stores may...
Mobile Actin Clusters and Traveling Waves in Cells Recovering from Actin (2004)
Günther Gerisch, Till Bretschneider, Annette Müller-taubenberger, Evelyn Simmeth, Mary Ecke, Stefan Diez, ...
ABSTRACT At the leading edge of a motile cell, actin polymerizes in close apposition to the plasma membrane. Here we ask how the machinery for force generation at a leading edge is established de...
Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis
Müller-Taubenberger, Annette, Lupas, Andrei N., Li, Hewang, Ecke, Mary, Simmeth, Evelyn, Gerisch, Günther
Calreticulin and calnexin are Ca2+-binding proteins with chaperone activity in the endoplasmic reticulum. These proteins have been eliminated by gene replacement in Dictyostelium, the only...
Subsecond reorganization of the actin network in cell motility and chemotaxis
Diez, Stefan, Gerisch, Günther, Anderson, Kurt, Müller-Taubenberger, Annette, Bretschneider, Till
Actin networks are continuously reorganized in cells that rapidly change their shape. Applying total internal reflection fluorescence microscopy at acquisition rates of 10–20 Hz, we measured an...
Wilczynska, Zofia, Happle, Kathrin, Müller-Taubenberger, Annette, Schlatterer, Christina, Malchow, Dieter, Fisher, Paul R.
Ca2+ responses to two chemoattractants, folate and cyclic AMP (cAMP), were assayed in Dictyostelium D. discoideum mutants deficient in one or both of two abundant Ca2+-binding proteins of the...
Mobile Actin Clusters and Traveling Waves in Cells Recovering from Actin Depolymerization
Gerisch, Günther, Bretschneider, Till, Müller-Taubenberger, Annette, Simmeth, Evelyn, Ecke, Mary, Diez, Stefan, ...
At the leading edge of a motile cell, actin polymerizes in close apposition to the plasma membrane. Here we ask how the machinery for force generation at a leading edge is established de novo after...
Malchow, Dieter, Lusche, Daniel F, Schlatterer, Christina, De Lozanne, Arturo, Müller-Taubenberger, Annette
Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis
Müller-Taubenberger, Annette, Lupas, Andrei N., Li, Hewang, Ecke, Mary, Simmeth, Evelyn, Gerisch, Günther
Calreticulin and calnexin are Ca2+-binding proteins with chaperone activity in the endoplasmic reticulum. These proteins have been eliminated by gene replacement in Dictyostelium, the only...
Subsecond reorganization of the actin network in cell motility and chemotaxis
Diez, Stefan, Gerisch, Günther, Anderson, Kurt, Müller-Taubenberger, Annette, Bretschneider, Till
Actin networks are continuously reorganized in cells that rapidly change their shape. Applying total internal reflection fluorescence microscopy at acquisition rates of 10–20 Hz, we measured an...
Wilczynska, Zofia, Happle, Kathrin, Müller-Taubenberger, Annette, Schlatterer, Christina, Malchow, Dieter, Fisher, Paul R.
Ca2+ responses to two chemoattractants, folate and cyclic AMP (cAMP), were assayed in Dictyostelium D. discoideum mutants deficient in one or both of two abundant Ca2+-binding proteins of the...
Mobile Actin Clusters and Traveling Waves in Cells Recovering from Actin Depolymerization
Gerisch, Günther, Bretschneider, Till, Müller-Taubenberger, Annette, Simmeth, Evelyn, Ecke, Mary, Diez, Stefan, ...
At the leading edge of a motile cell, actin polymerizes in close apposition to the plasma membrane. Here we ask how the machinery for force generation at a leading edge is established de novo after...
Malchow, Dieter, Lusche, Daniel F, Schlatterer, Christina, De Lozanne, Arturo, Müller-Taubenberger, Annette
Mechanically Induced Actin-mediated Rocketing of Phagosomes
Clarke, Margaret, Müller-Taubenberger, Annette, Anderson, Kurt I., Engel, Ulrike, Gerisch, Günther
Actin polymerization can be induced in Dictyostelium by compressing the cells to bring phagosomes filled with large particles into contact with the plasma membrane. Asymmetric actin assembly results...
Attenuation of Phospholipid Signaling Provides a Novel Mechanism for the Action of Valproic Acid▿ †
Xu, Xuehua, Müller-Taubenberger, Annette, Adley, Kathryn E., Pawolleck, Nadine, Lee, Vivian W. Y., Wiedemann, Claudia, ...
Valproic acid (VPA) is used to treat epilepsy and bipolar disorder and to prevent migraine. It is also undergoing trials for cancer therapy. However, the biochemical and molecular biological actions...
Niewöhner, Jens, Weber, Igor, Maniak, Markus, Müller-Taubenberger, Annette, Gerisch, Günther
Dictyostelium discoideum contains a full-length homologue of talin, a protein implicated in linkage of the actin system to sites of cell-to-substrate adhesion in fibroblasts and neuronal growth...
Konzok, Angelika, Weber, Igor, Simmeth, Evelyn, Hacker, Ulrike, Maniak, Markus, Müller-Taubenberger, Annette
The 64-kD protein DAip1 from Dictyostelium contains nine WD40-repeats and is homologous to the actin-interacting protein 1, Aip1p, from Saccharomyces cerevisiae, and to related proteins from...
Joseph, Jayabalan M., Fey, Petra, Ramalingam, Nagendran, Liu, Xiao I., Rohlfs, Meino, Noegel, Angelika A., ...
Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps). To get an overview over the sometimes...
Overlapping Functions of the Two Talin Homologues in Dictyostelium▿ ‡
Tsujioka, Masatsune, Yoshida, Kunito, Nagasaki, Akira, Yonemura, Shigenobu, Müller-Taubenberger, Annette, Uyeda, Taro Q. P.
Talin is a cytoskeletal protein involved in constructing and regulating focal adhesions in animal cells. The cellular slime mold Dictyostelium discoideum has two talin homologues, talA and talB, and...
Dalous, Jérémie, Burghardt, Emmanuel, Müller-Taubenberger, Annette, Bruckert, Franz, Gerisch, Günther, Bretschneider, Till
To study reorganization of the actin system in cells that invert their polarity, we stimulated Dictyostelium cells by mechanical forces from alternating directions. The cells oriented in a fluid flow...