Anthony J. Wilkinson

FUNCTIONAL ROLE FOR A CONSERVED ASPARTATE IN THE Spo0E SIGNATURE MOTIF INVOLVED IN THE DEPHOSPHORYLATION OF THE BACILLUS SUBTILIS SPORULATION REGULATOR Spo0A (2008)

Ra R. Diaz, Sophie Stephenson, J. Michael Green, Vladimir M. Levdikov, Anthony J. Wilkinson, Marta Perego

Sporulation is a complex developmental system characterizing Gram-positive bacteria of the genus Bacillus and Clostridium. In Bacillus subtilis the phosphorelay signal transduction system regulates...

The crystal structure of superoxide dismutase from Plasmodium falciparum (2006)

Boucher, Ian W, Brzozowski, Andrzej M, Brannigan, James A, Schnick, Claudia, Smith, Derek J, Kyes, Sue A, ...

Abstract Background Superoxide dismutases (SODs) are important enzymes in defence against oxidative stress. In Plasmodium falciparum , they may be expected to have special significance since part of...

Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli (1988)

Dodson, Guy, Hubbard, Roderick E., Oldfield, Tom J., Smerdon, Stephen J., Wilkinson, Anthony J.

Recombinant porcine myoglobin has been produced in Escherichia coli using the λ cII fusion expression system of Nagai and Th�gersen [Nature, 309, 810–812 (1984)]. After processing and...

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum

Boucher, Ian W, McMillan, Paul J, Gabrielsen, Mads, Akerman, Susan E, Brannigan, James A, Schnick, Claudia, ...

Plasmodium falciparum possesses a single mitochondrion with a functional electron transport chain. During respiration, reactive oxygen species are generated that need to be removed to protect the...

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum

Boucher, Ian W, McMillan, Paul J, Gabrielsen, Mads, Akerman, Susan E, Brannigan, James A, Schnick, Claudia, ...

Plasmodium falciparum possesses a single mitochondrion with a functional electron transport chain. During respiration, reactive oxygen species are generated that need to be removed to protect the...

Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis

Grenha, Rosa, Levdikov, Vladimir M., Fogg, Mark J., Blagova, Elena V., Brannigan, James A., Wilkinson, Anthony J., ...

The crystal structure of purine nucleoside phosphorylase (DeoD) from B. anthracis was solved by X-ray crystallography using molecular replacement and refined at a resolution of 2.24 Å.

Structures of two superoxide dismutases from Bacillus anthracis reveal a novel active centre

Boucher, Ian W., Kalliomaa, Anne K., Levdikov, Vladimir M., Blagova, Elena V., Fogg, Mark J., Brannigan, James A., ...

The crystal structures of two manganese superoxide dismutases from B. anthracis were solved by X-ray crystallography using molecular replacement.

Lipid spirals in Bacillus subtilis and their role in cell division

Barák, Imrich, Muchová, Katarína, Wilkinson, Anthony J, O'Toole, Peter J, Pavlendová, Nada

The fluid mosaic model of membrane structure has been revised in recent years as it has become evident that domains of different lipid composition are present in eukaryotic and prokaryotic cells....

Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages

Schnick, Claudia, Polley, Spencer D, Fivelman, Quinton L, Ranford-Cartwright, Lisa C, Wilkinson, Shane R, Brannigan, James A, ...

Malaria pathology is caused by multiplication of asexual parasites within erythrocytes, whereas mosquito transmission of malaria is mediated by sexual precursor cells (gametocytes). Microarray...