Dostie, Josee, Richmond, Joann M., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Brunvand, Mark W., Krumm, Anton, Groudine, Mark
The IL-2 gene is a T cell specific gene that is expressed early during the activation-specific T lymphocyte development program. Electrophoretic mobility shift assay (EMSA) and DNase I footprinting...
Long-distance transcriptional enhancement by the histone acetyltransferase PCAF
Krumm, Anton, Madisen, Linda, Yang, Xiang-Jiao, Goodman, Richard, Nakatani, Yoshihiro, Groudine, Mark
Enhancers are defined by their ability to stimulate gene activity from remote sites and their requirement for promoter-proximal upstream activators to activate transcription. Here we demonstrate that...
Promoter-Specific Targeting of Human SWI-SNF Complex by Epstein-Barr Virus Nuclear Protein 2
Wu, Daniel Y., Krumm, Anton, Schubach, William H.
The multiprotein human SWI-SNF (hSWI-SNF) complex is a chromatin-remodeling machine that facilitates transcription by overcoming chromatin-mediated gene repression. We had previously shown that...
Madisen, Linda, Krumm, Anton, Hebbes, Tim R., Groudine, Mark
In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become juxtaposed to immunoglobulin heavy-chain (IgH) sequences, resulting in aberrant...
The c-myc Insulator Element and Matrix Attachment Regions Define the c-myc Chromosomal Domain
Gombert, Wendy M., Farris, Stephen D., Rubio, Eric D., Morey-Rosler, Kristin M., Schubach, William H., Krumm, Anton
Insulator elements and matrix attachment regions are essential for the organization of genetic information within the nucleus. By comparing the pattern of histone modifications at the mouse and human...
Long-distance transcriptional enhancement by the histone acetyltransferase PCAF
Krumm, Anton, Madisen, Linda, Yang, Xiang-Jiao, Goodman, Richard, Nakatani, Yoshihiro, Groudine, Mark
Enhancers are defined by their ability to stimulate gene activity from remote sites and their requirement for promoter-proximal upstream activators to activate transcription. Here we demonstrate that...
Promoter-Specific Targeting of Human SWI-SNF Complex by Epstein-Barr Virus Nuclear Protein 2
Wu, Daniel Y., Krumm, Anton, Schubach, William H.
The multiprotein human SWI-SNF (hSWI-SNF) complex is a chromatin-remodeling machine that facilitates transcription by overcoming chromatin-mediated gene repression. We had previously shown that...
Madisen, Linda, Krumm, Anton, Hebbes, Tim R., Groudine, Mark
In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become juxtaposed to immunoglobulin heavy-chain (IgH) sequences, resulting in aberrant...
The c-myc Insulator Element and Matrix Attachment Regions Define the c-myc Chromosomal Domain
Gombert, Wendy M., Farris, Stephen D., Rubio, Eric D., Morey-Rosler, Kristin M., Schubach, William H., Krumm, Anton
Insulator elements and matrix attachment regions are essential for the organization of genetic information within the nucleus. By comparing the pattern of histone modifications at the mouse and human...
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
CTCF physically links cohesin to chromatin
Rubio, Eric D., Reiss, David J., Welcsh, Piri L., Disteche, Christine M., Filippova, Galina N., Baliga, Nitin S., ...
Cohesin is required to prevent premature dissociation of sister chromatids after DNA replication. Although its role in chromatid cohesion is well established, the functional significance of cohesin's...