The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation (2009)
Claudio, Estefania, Sonder, Soren Ulrik, Saret, Sun, Carvalho, Gabrielle, Ramalingam, Thirumalai R., Wynn, Thomas A., ...
IL-17 is the signature cytokine of recently discovered Th type 17 (Th17) cells, which are prominent in defense against extracellular bacteria and fungi as well as in autoimmune diseases, such as...
Role of the adaptor protein CIKS in the activation of the IKK complex (2003)
Mauro, Claudio, Vito, Pasquale, Mellone, Stefano, Pacifico, Francesco, Chariot, Alain, Formisano, Silvestro, ...
Nuclear factor kappaB (NF-kappaB) plays a pivotal role in numerous cellular processes, including stress response, inflammation, and protection from apoptosis. Therefore, the activity of NF-kappaB...
Chariot, Alain, Leonardi, Antonio, Muller, Jean-Noel, Bonif, Marianne, Brown, Keith, Siebenlist, Ulrich
Canonical activation of NF-kappaB is mediated via phosphorylation of the inhibitory IkappaB proteins by the IkappaB kinase complex (IKK). IKK is composed of a heterodimer of the catalytic IKKalpha...
CIKS, a connection to Ikappa B kinase and stress-activated protein kinase. (2000)
Leonardi, Antonio, Chariot, Alain, Claudio, Estefania, Cunningham, Kirk, Siebenlist, Ulrich
Pathogens, inflammatory signals, and stress cause acute transcriptional responses in cells. The induced expression of genes in response to these signals invariably involves transcription factors of...
Il mondo dei computer, Antonio Leonardi. . - Rimini. NALUAF000640, Idea Libri. NAEDAF002746, 1999.
CIKS, a connection to IκB kinase and stress-activated protein kinase
Leonardi, Antonio, Chariot, Alain, Claudio, Estefania, Cunningham, Kirk, Siebenlist, Ulrich
Pathogens, inflammatory signals, and stress cause acute transcriptional responses in cells. The induced expression of genes in response to these signals invariably involves transcription factors of...
Requirement for NF-κB in osteoclast and B-cell development
Franzoso, Guido, Carlson, Louise, Xing, Lianping, Poljak, Ljiljana, Shores, Elizabeth W., Brown, Keith D., ...
NF-κB is a family of related, dimeric transcription factors that are readily activated in cells by signals associated with stress or pathogens. These factors are critical to host defense, as...
Di Jeso, Bruno, Ulianich, Luca, Pacifico, Francesco, Leonardi, Antonio, Vito, Pasquale, Consiglio, Eduardo, ...
During its initial folding in the endoplasmic reticulum (ER), newly synthesized thyroglobulin (Tg) is known to interact with calnexin and other ER molecular chaperones, but its interaction with...
CIKS, a connection to IκB kinase and stress-activated protein kinase
Leonardi, Antonio, Chariot, Alain, Claudio, Estefania, Cunningham, Kirk, Siebenlist, Ulrich
Pathogens, inflammatory signals, and stress cause acute transcriptional responses in cells. The induced expression of genes in response to these signals invariably involves transcription factors of...
Requirement for NF-κB in osteoclast and B-cell development
Franzoso, Guido, Carlson, Louise, Xing, Lianping, Poljak, Ljiljana, Shores, Elizabeth W., Brown, Keith D., ...
NF-κB is a family of related, dimeric transcription factors that are readily activated in cells by signals associated with stress or pathogens. These factors are critical to host defense, as...
Di Jeso, Bruno, Ulianich, Luca, Pacifico, Francesco, Leonardi, Antonio, Vito, Pasquale, Consiglio, Eduardo, ...
During its initial folding in the endoplasmic reticulum (ER), newly synthesized thyroglobulin (Tg) is known to interact with calnexin and other ER molecular chaperones, but its interaction with...
Franzoso, Guido, Carlson, Louise, Poljak, Ljiljana, Shores, Elizabeth W., Epstein, Suzanne, Leonardi, Antonio, ...
p52 is a subunit of nuclear factor (NF)-κB transcription factors, most closely related to p50. Previously, we have shown that p52, but not p50 homodimers can form transactivating complexes when...
Iannetti, Alessio, Pacifico, Francesco, Acquaviva, Renato, Lavorgna, Alfonso, Crescenzi, Elvira, Vascotto, Carlo, ...
NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell line,...
Vascotto, Carlo, Fantini, Damiano, Romanello, Milena, Cesaratto, Laura, Deganuto, Marta, Leonardi, Antonio, ...
APE1/Ref-1 (hereafter, APE1), a DNA repair enzyme and a transcriptional coactivator, is a vital protein in mammals. Its role in controlling cell growth and the molecular mechanisms that fine-tune its...