Harada, Hisashi, Quearry, Bonnie, Ruiz-Vela, Antonio, Korsmeyer, Stanley J.
The “BH3-only” proapoptotic BCL-2 family members initiate the intrinsic apoptotic pathway. A small interfering RNA knockdown of BIM confirms this BH3-only member is important for the...
Proapoptotic BAX and BAK control multiple initiator caspases
Ruiz-Vela, Antonio, Opferman, Joseph T, Cheng, Emily H-Y, Korsmeyer, Stanley J
BAX and BAK operate at both the mitochondria and endoplasmic reticulum (ER) to regulate the intrinsic apoptotic pathway. An unresolved issue is whether any caspases can be activated in response to...
Harada, Hisashi, Quearry, Bonnie, Ruiz-Vela, Antonio, Korsmeyer, Stanley J.
The “BH3-only” proapoptotic BCL-2 family members initiate the intrinsic apoptotic pathway. A small interfering RNA knockdown of BIM confirms this BH3-only member is important for the...
Proapoptotic BAX and BAK control multiple initiator caspases
Ruiz-Vela, Antonio, Opferman, Joseph T, Cheng, Emily H-Y, Korsmeyer, Stanley J
BAX and BAK operate at both the mitochondria and endoplasmic reticulum (ER) to regulate the intrinsic apoptotic pathway. An unresolved issue is whether any caspases can be activated in response to...
The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival
Mandal, Malay, Borowski, Christine, Palomero, Teresa, Ferrando, Adolfo A., Oberdoerffer, Philipp, Meng, Fanyong, ...
The pre–T cell receptor (TCR) is expressed early during T cell development and imposes a tight selection for differentiating T cell progenitors. Pre-TCR–expressing cells are selected to survive...
Ruiz-Vela, Antonio, Serrano, Fernando, González, Manuel A., Abad, José Luis, Bernad, Antonio, Maki, Masatoshi, ...
Long-term cultured pre-B cells are able to differentiate into immunoglobulin (Ig)M-positive B cells (IgM+ cells) when transplanted into severe combined immunodeficient (SCID) mice. Based on previous...