Stochastic mRNA Synthesis in Mammalian Cells (2006)
Arjun Raj, Charles S. Peskin, Daniel Tranchina, Diana Y. Vargas, Sanjay Tyagi
Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the origins of these variations in mammalian...
Mechanism of mRNA transport in the nucleus
Vargas, Diana Y., Raj, Arjun, Marras, Salvatore A. E., Kramer, Fred Russell, Tyagi, Sanjay
The mechanism of transport of mRNA-protein (mRNP) complexes from transcription sites to nuclear pores has been the subject of many studies. Using molecular beacons to track single mRNA molecules in...
The influence of chromosome flexibility on chromosome transport during anaphase A
Raj, Arjun, Peskin, Charles S.
The role of protein flexibility in molecular motor function has previously been studied by considering a Brownian ratchet motor that is connected to its cargo by an elastic spring, with the result...
Stochastic mRNA Synthesis in Mammalian Cells
Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay
Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the origins of these variations in mammalian...
Mechanism of mRNA transport in the nucleus
Vargas, Diana Y., Raj, Arjun, Marras, Salvatore A. E., Kramer, Fred Russell, Tyagi, Sanjay
The mechanism of transport of mRNA-protein (mRNP) complexes from transcription sites to nuclear pores has been the subject of many studies. Using molecular beacons to track single mRNA molecules in...
The influence of chromosome flexibility on chromosome transport during anaphase A
Raj, Arjun, Peskin, Charles S.
The role of protein flexibility in molecular motor function has previously been studied by considering a Brownian ratchet motor that is connected to its cargo by an elastic spring, with the result...
Stochastic mRNA Synthesis in Mammalian Cells
Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay
Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the origins of these variations in mammalian...
Khalil, Ahmad M., Guttman, Mitchell, Huarte, Maite, Garber, Manuel, Raj, Arjun, Rivea Morales, Dianali, ...
We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns have...