Arthur M. Buchberg

The modifier of Min 2 (Mom2) locus: Embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression (2007)

Baran, Amy A., Silverman, Karen A., Zeskand, Joseph, Koratkar, Revati, Palmer, Ashley, McCullen, Kristen, ...

Inactivation of the APC gene is considered the initiating event in human colorectal cancer. Modifier genes that influence the penetrance of mutations in tumor-suppressor genes hold great potential...

A novel transgenic line of mice exhibiting autosomal recessive male-specific lethality and non-alcoholic fatty liver disease (2002)

Sollars, Vincent E., McEntee, Benjamin J., Engiles, Julie B., Rothstein, Jay L., Buchberg, Arthur M.

We have isolated a Meis1a transgenic mouse line exhibiting recessive male-specific lethality and non-alcoholic fatty liver disease (NAFLD), which coincides with pubescence and is androgen-dependent....

cDNA sequence and genomic structure of EVI2B, a gene lying within an intron of the neurofibromatosis type 1 gene (1991)

Cawthon, Richard M., Andersen, Lone B., Buchberg, Arthur M., Xu, Gangfeng, O'Connell, Peter, Viskochil, David, ...

The gene responsible for neurofibromatosis type 1 (NF1), one of the more common inherited human disorders, was identified recently, and segments of it were cloned. Two translocation breakpoints that...

The human homolog of murine Evi-2 lies between two von Recklinghausen neurofibromatosis translocations (1990)

O'Connell, Peter, Viskochil, David, Buchberg, Arthur M., Fountain, Jane W., Cawthon, Richard M., Culver, Melanie, ...

Von Recklinghausen neurofibromatosis (NF1) is one of the most common inherited human disorders. The genetic locus that harbors the mutation(s) responsible for NF1 is near the centromere of chromosome...

Induction of liver apolipoprotein A-IV mRNA in porphyric mice (1985)

Buchberg, Arthur M., Kinniburgh, Alan J.

We have isolated cDNA clones for mRNAS that are Induced by porphyria from a mouse liver library. Of the three inducible clones isolated, we have identified one as being apolipoprotein A-IV (apo A-IV)...

Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans

Pekarsky, Yuri, Campiglio, Manuela, Siprashvili, Zurab, Druck, Teresa, Sedkov, Yurii, Tillib, Sergei, ...

The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT...

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

Swift, Galvin H., Liu, Ying, Rose, Scott D., Bischof, Larry J., Steelman, Scott, Buchberg, Arthur M., ...

HOX proteins and some orphan homeodomain proteins form complexes with either PBX or MEIS subclasses of homeodomain proteins. This interaction can increase the binding specificity and transcriptional...

Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos

Maeda, Ryu, Ishimura, Akihiko, Mood, Kathleen, Park, Eui Kyun, Buchberg, Arthur M., Daar, Ira O.

Pbx1 is a homeodomain protein that functions in complexes with other homeodomain-containing proteins to regulate gene expression during embryogenesis and oncogenesis. Pbx proteins bind DNA...

Identification of the Modifier of Min 2 (Mom2) Locus, a New Mutation That Influences Apc-Induced Intestinal Neoplasia

Silverman, Karen A., Koratkar, Revati, Siracusa, Linda D., Buchberg, Arthur M.

Min (Multiple intestinal neoplasia) mice carry a dominant mutation in the adenomatous polyposis coli (Apc) gene and develop multiple adenomas throughout their intestinal tract (Moser et al. 1990; Su...

Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans

Pekarsky, Yuri, Campiglio, Manuela, Siprashvili, Zurab, Druck, Teresa, Sedkov, Yurii, Tillib, Sergei, ...

The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT...

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

Swift, Galvin H., Liu, Ying, Rose, Scott D., Bischof, Larry J., Steelman, Scott, Buchberg, Arthur M., ...

HOX proteins and some orphan homeodomain proteins form complexes with either PBX or MEIS subclasses of homeodomain proteins. This interaction can increase the binding specificity and transcriptional...

Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos

Maeda, Ryu, Ishimura, Akihiko, Mood, Kathleen, Park, Eui Kyun, Buchberg, Arthur M., Daar, Ira O.

Pbx1 is a homeodomain protein that functions in complexes with other homeodomain-containing proteins to regulate gene expression during embryogenesis and oncogenesis. Pbx proteins bind DNA...

Identification of the Modifier of Min 2 (Mom2) Locus, a New Mutation That Influences Apc-Induced Intestinal Neoplasia

Silverman, Karen A., Koratkar, Revati, Siracusa, Linda D., Buchberg, Arthur M.

Min (Multiple intestinal neoplasia) mice carry a dominant mutation in the adenomatous polyposis coli (Apc) gene and develop multiple adenomas throughout their intestinal tract (Moser et al. 1990; Su...

The modifier of Min 2 (Mom2) locus: Embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression

Baran, Amy A., Silverman, Karen A., Zeskand, Joseph, Koratkar, Revati, Palmer, Ashley, McCullen, Kristen, ...

Inactivation of the APC gene is considered the initiating event in human colorectal cancer. Modifier genes that influence the penetrance of mutations in tumor-suppressor genes hold great potential...