Baran, Amy A., Silverman, Karen A., Zeskand, Joseph, Koratkar, Revati, Palmer, Ashley, McCullen, Kristen, ...
Inactivation of the APC gene is considered the initiating event in human colorectal cancer. Modifier genes that influence the penetrance of mutations in tumor-suppressor genes hold great potential...
Marina Markova, Revati A Koratkar, Karen A Silverman, Vincent E Sollars, Melina MacPhee-Pellini, Rhonda Walters, ...
Sollars, Vincent E., McEntee, Benjamin J., Engiles, Julie B., Rothstein, Jay L., Buchberg, Arthur M.
We have isolated a Meis1a transgenic mouse line exhibiting recessive male-specific lethality and non-alcoholic fatty liver disease (NAFLD), which coincides with pubescence and is androgen-dependent....
Camper, Sally A., Buchberg, Arthur M., Buckwalter, Marion S.
Peer Reviewed
Cawthon, Richard M., Andersen, Lone B., Buchberg, Arthur M., Xu, Gangfeng, O'Connell, Peter, Viskochil, David, ...
The gene responsible for neurofibromatosis type 1 (NF1), one of the more common inherited human disorders, was identified recently, and segments of it were cloned. Two translocation breakpoints that...
O'Connell, Peter, Viskochil, David, Buchberg, Arthur M., Fountain, Jane W., Cawthon, Richard M., Culver, Melanie, ...
Von Recklinghausen neurofibromatosis (NF1) is one of the most common inherited human disorders. The genetic locus that harbors the mutation(s) responsible for NF1 is near the centromere of chromosome...
Induction of liver apolipoprotein A-IV mRNA in porphyric mice (1985)
Buchberg, Arthur M., Kinniburgh, Alan J.
We have isolated cDNA clones for mRNAS that are Induced by porphyria from a mouse liver library. Of the three inducible clones isolated, we have identified one as being apolipoprotein A-IV (apo A-IV)...
Pekarsky, Yuri, Campiglio, Manuela, Siprashvili, Zurab, Druck, Teresa, Sedkov, Yurii, Tillib, Sergei, ...
The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT...
Swift, Galvin H., Liu, Ying, Rose, Scott D., Bischof, Larry J., Steelman, Scott, Buchberg, Arthur M., ...
HOX proteins and some orphan homeodomain proteins form complexes with either PBX or MEIS subclasses of homeodomain proteins. This interaction can increase the binding specificity and transcriptional...
Maeda, Ryu, Ishimura, Akihiko, Mood, Kathleen, Park, Eui Kyun, Buchberg, Arthur M., Daar, Ira O.
Pbx1 is a homeodomain protein that functions in complexes with other homeodomain-containing proteins to regulate gene expression during embryogenesis and oncogenesis. Pbx proteins bind DNA...
Silverman, Karen A., Koratkar, Revati, Siracusa, Linda D., Buchberg, Arthur M.
Min (Multiple intestinal neoplasia) mice carry a dominant mutation in the adenomatous polyposis coli (Apc) gene and develop multiple adenomas throughout their intestinal tract (Moser et al. 1990; Su...
Pekarsky, Yuri, Campiglio, Manuela, Siprashvili, Zurab, Druck, Teresa, Sedkov, Yurii, Tillib, Sergei, ...
The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT...
Swift, Galvin H., Liu, Ying, Rose, Scott D., Bischof, Larry J., Steelman, Scott, Buchberg, Arthur M., ...
HOX proteins and some orphan homeodomain proteins form complexes with either PBX or MEIS subclasses of homeodomain proteins. This interaction can increase the binding specificity and transcriptional...
Maeda, Ryu, Ishimura, Akihiko, Mood, Kathleen, Park, Eui Kyun, Buchberg, Arthur M., Daar, Ira O.
Pbx1 is a homeodomain protein that functions in complexes with other homeodomain-containing proteins to regulate gene expression during embryogenesis and oncogenesis. Pbx proteins bind DNA...
Silverman, Karen A., Koratkar, Revati, Siracusa, Linda D., Buchberg, Arthur M.
Min (Multiple intestinal neoplasia) mice carry a dominant mutation in the adenomatous polyposis coli (Apc) gene and develop multiple adenomas throughout their intestinal tract (Moser et al. 1990; Su...
Baran, Amy A., Silverman, Karen A., Zeskand, Joseph, Koratkar, Revati, Palmer, Ashley, McCullen, Kristen, ...
Inactivation of the APC gene is considered the initiating event in human colorectal cancer. Modifier genes that influence the penetrance of mutations in tumor-suppressor genes hold great potential...