Ashley P. Barry

Induction of Neutralizing Antibodies and Gag-Specific Cellular Immune Responses to an R5 Primary Isolate of Human Immunodeficiency Virus Type 1 in Rhesus Macaques

Montefiori, David C., Safrit, Jeffrey T., Lydy, Shari L., Barry, Ashley P., Bilska, Miroslawa, Vo, Ha T. T., ...

The ability to generate antibodies that cross-neutralize diverse primary isolates is an important goal for human immunodeficiency virus type 1 (HIV-1) vaccine development. Most of the candidate HIV-1...

Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication

Garber, David A., Silvestri, Guido, Barry, Ashley P., Fedanov, Andrew, Kozyr, Natalia, McClure, Harold, ...

In vivo blockade of CD28 and CD40 T cell costimulation pathways during acute simian immunodeficiency virus (SIV) infection of rhesus macaques was performed to assess the relative contributions of...

Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein

Staprans, Silvija I., Barry, Ashley P., Silvestri, Guido, Safrit, Jeffrey T., Kozyr, Natalia, Sumpter, Beth, ...

Given the dual role of CD4 T cells as both immune effectors and targets for HIV infection, the balance of CD4 versus CD8 T cell-mediated responses induced by candidate AIDS vaccines may be critical...

Induction of Neutralizing Antibodies and Gag-Specific Cellular Immune Responses to an R5 Primary Isolate of Human Immunodeficiency Virus Type 1 in Rhesus Macaques

Montefiori, David C., Safrit, Jeffrey T., Lydy, Shari L., Barry, Ashley P., Bilska, Miroslawa, Vo, Ha T. T., ...

The ability to generate antibodies that cross-neutralize diverse primary isolates is an important goal for human immunodeficiency virus type 1 (HIV-1) vaccine development. Most of the candidate HIV-1...

Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication

Garber, David A., Silvestri, Guido, Barry, Ashley P., Fedanov, Andrew, Kozyr, Natalia, McClure, Harold, ...

In vivo blockade of CD28 and CD40 T cell costimulation pathways during acute simian immunodeficiency virus (SIV) infection of rhesus macaques was performed to assess the relative contributions of...

Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein

Staprans, Silvija I., Barry, Ashley P., Silvestri, Guido, Safrit, Jeffrey T., Kozyr, Natalia, Sumpter, Beth, ...

Given the dual role of CD4 T cells as both immune effectors and targets for HIV infection, the balance of CD4 versus CD8 T cell-mediated responses induced by candidate AIDS vaccines may be critical...

Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys

Muthukumar, Alagarraju, Zhou, Dejiang, Paiardini, Mirko, Barry, Ashley P., Cole, Kelly S., McClure, Harold M., ...

Sooty mangabeys, the natural host of simian immunodeficiency virus (SIVsm), generally avoid progressive depletion of CD4+ T cells and opportunistic infections associated with infection of humans...