Panigrahi, Aswini K., Gygi, Steven P., Ernst, Nancy L., Igo, Robert P., Palazzo, Setareh S., Schnaufer, Achim, ...
RNA editing in kinetoplastid mitochondria inserts and deletes uridylates at multiple sites in pre-mRNAs as directed by guide RNAs. This occurs by a series of steps that are catalyzed by...
Four Related Proteins of the Trypanosoma brucei RNA Editing Complex
Panigrahi, Aswini K., Schnaufer, Achim, Carmean, Nicole, Igo, Robert P., Gygi, Steven P., Ernst, Nancy L., ...
RNA editing in kinetoplastid mitochondria occurs by a series of enzymatic steps that is catalyzed by a macromolecular complex. Four novel proteins and their corresponding genes were identified by...
Igo, Robert P., Palazzo, Setareh S., Burgess, Moffett L. K., Panigrahi, Aswini K., Stuart, Kenneth
RNA editing in Trypanosoma brucei inserts and deletes uridylates (U's) in mitochondrial pre-mRNAs under the direction of guide RNAs (gRNAs). We report here the development of a novel in vitro...
Role of Uridylate-Specific Exoribonuclease Activity in Trypanosoma brucei RNA Editing
Igo, Robert P., Weston, David S., Ernst, Nancy Lewis, Panigrahi, Aswini K., Salavati, Reza, Stuart, Kenneth
Editing of mitochondrial mRNAs in kinetoplastid protozoa occurs by a series of enzymatic steps that insert and delete uridylates (U's) as specified by guide RNAs (gRNAs). The characteristics of the...
TbMP44 Is Essential for RNA Editing and Structural Integrity of the Editosome in Trypanosoma brucei
Wang, Bingbing, Ernst, Nancy Lewis, Palazzo, Setareh S., Panigrahi, Aswini K., Salavati, Reza, Stuart, Kenneth
RNA editing produces mature mitochondrial mRNAs in trypanosomatids by the insertion and deletion of uridylates. It is catalyzed by a multiprotein complex, the editosome. We identified TbMP44 among...
Identification of novel components of Trypanosoma brucei editosomes
PANIGRAHI, ASWINI K., SCHNAUFER, ACHIM, ERNST, NANCY L., WANG, BINGBING, CARMEAN, NICOLE, SALAVATI, REZA, ...
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome...
Compositionally and functionally distinct editosomes in Trypanosoma brucei
Panigrahi, Aswini K., Ernst, Nancy Lewis, Domingo, Gonzalo J., Fleck, Michele, Salavati, Reza, Stuart, Kenneth D.
Uridylate insertion/deletion RNA editing in Trypanosoma brucei mitochondria is catalyzed by a multiprotein complex, the ∼20S editosome. Editosomes purified via three related tagged RNase III...
Panigrahi, Aswini K., Gygi, Steven P., Ernst, Nancy L., Igo, Robert P., Palazzo, Setareh S., Schnaufer, Achim, ...
RNA editing in kinetoplastid mitochondria inserts and deletes uridylates at multiple sites in pre-mRNAs as directed by guide RNAs. This occurs by a series of steps that are catalyzed by...
Four Related Proteins of the Trypanosoma brucei RNA Editing Complex
Panigrahi, Aswini K., Schnaufer, Achim, Carmean, Nicole, Igo, Robert P., Gygi, Steven P., Ernst, Nancy L., ...
RNA editing in kinetoplastid mitochondria occurs by a series of enzymatic steps that is catalyzed by a macromolecular complex. Four novel proteins and their corresponding genes were identified by...
Igo, Robert P., Palazzo, Setareh S., Burgess, Moffett L. K., Panigrahi, Aswini K., Stuart, Kenneth
RNA editing in Trypanosoma brucei inserts and deletes uridylates (U's) in mitochondrial pre-mRNAs under the direction of guide RNAs (gRNAs). We report here the development of a novel in vitro...
Role of Uridylate-Specific Exoribonuclease Activity in Trypanosoma brucei RNA Editing
Igo, Robert P., Weston, David S., Ernst, Nancy Lewis, Panigrahi, Aswini K., Salavati, Reza, Stuart, Kenneth
Editing of mitochondrial mRNAs in kinetoplastid protozoa occurs by a series of enzymatic steps that insert and delete uridylates (U's) as specified by guide RNAs (gRNAs). The characteristics of the...
TbMP44 Is Essential for RNA Editing and Structural Integrity of the Editosome in Trypanosoma brucei
Wang, Bingbing, Ernst, Nancy Lewis, Palazzo, Setareh S., Panigrahi, Aswini K., Salavati, Reza, Stuart, Kenneth
RNA editing produces mature mitochondrial mRNAs in trypanosomatids by the insertion and deletion of uridylates. It is catalyzed by a multiprotein complex, the editosome. We identified TbMP44 among...
Identification of novel components of Trypanosoma brucei editosomes
PANIGRAHI, ASWINI K., SCHNAUFER, ACHIM, ERNST, NANCY L., WANG, BINGBING, CARMEAN, NICOLE, SALAVATI, REZA, ...
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome...
Compositionally and functionally distinct editosomes in Trypanosoma brucei
Panigrahi, Aswini K., Ernst, Nancy Lewis, Domingo, Gonzalo J., Fleck, Michele, Salavati, Reza, Stuart, Kenneth D.
Uridylate insertion/deletion RNA editing in Trypanosoma brucei mitochondria is catalyzed by a multiprotein complex, the ∼20S editosome. Editosomes purified via three related tagged RNase III...
Hashimi, Hassan, Zíková, Alena, Panigrahi, Aswini K., Stuart, Kenneth D., Lukeš, Julius
The uridine insertion/deletion RNA editing of kinetoplastid mitochondrial transcripts is performed by complex machinery involving a number of proteins and multiple protein complexes. Here we describe...