Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors (2008)
Trimis, George, Chatzistamou, Ioulia, Politi, Katerina, Kiaris, Hippokratis, Papavassiliou, Athanasios G.
During carcinogenesis, stromal fibroblasts undergo certain changes in concert with their neoplastic neighbors, an interaction that progressively leads to a cancer-associated state. However, despite...
PTGS2 (prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)) (2007)
Konstantinopoulos, Panagiotis A., Karamouzis, Michalis V., Papavassiliou, Athanasios G.
Smith, Susan E., Papavassiliou, Athanasios G., Bohmann, Dirk
Several promoter elements with sequence similarity to the prototype TPA-responsive element (TRE) were compared by mobility-shift analyses. Activities within whole cell extracts were identified that...
Interaction of virus nucleic acids with host and viral proteins / (1989)
Thesis (Ph. D.)--Columbia University, 1989.
p53 activates ICAM-1 (CD54) expression in an NF-κB-independent manner
Gorgoulis, Vassilis G., Zacharatos, Panayotis, Kotsinas, Athanassios, Kletsas, Dimitris, Mariatos, George, Zoumpourlis, Vassilis, ...
Intercellular adhesion molecule-1 (ICAM-1) is a crucial receptor in the cell–cell interaction, a process central to the reaction to all forms of injury. Its expression is upregulated in response to...
p53 activates ICAM-1 (CD54) expression in an NF-κB-independent manner
Gorgoulis, Vassilis G., Zacharatos, Panayotis, Kotsinas, Athanassios, Kletsas, Dimitris, Mariatos, George, Zoumpourlis, Vassilis, ...
Intercellular adhesion molecule-1 (ICAM-1) is a crucial receptor in the cell–cell interaction, a process central to the reaction to all forms of injury. Its expression is upregulated in response to...
Karakaidos, Panagiotis, Taraviras, Stavros, Vassiliou, Leandros V., Zacharatos, Panayotis, Kastrinakis, Nikolaos G., Kougiou, Dionysia, ...
Replication licensing ensures once per cell cycle replication and is essential for genome stability. Overexpression of two key licensing factors, Cdc6 and Cdt1, leads to overreplication and...
The progression in the mouse skin carcinogenesis model correlates with ERK1/2 signaling.
Katsanakis, Kostas D., Gorgoulis, Vassilis, Papavassiliou, Athanasios G., Zoumpourlis, Vassilis K.
BACKGROUND: The ras family of proto-oncogenes encodes for small GTPases that play critical roles in cell-cycle progression and cellular transformation. ERK1/2 MAP kinases are major ras effectors....
Koutsami, Marilena K., Doussis-Anagnostopoulou, Ipatia, Papavassiliou, Athanasios G., Gorgoulis, Vassilis G.
The aim of this review is to present the advances in our understanding of the progression of tumorigenesis in neuroendocrine lung tumors. Current information on established and putative diagnostic...
Papachristou, Dionysios J, Papadakou, Eugenia, Basdra, Efthimia K, Baltopoulos, Panagiotis, Panagiotopoulos, Elias, Papavassiliou, Athanasios G
Meniscal tears are attributed to either trauma or degeneration processes. Clinical data suggest that meniscal degeneration (MD) is associated with knee osteoarthritis; however, the molecular events...
Educational and Social-Ethical Issues in the Pursuit of Molecular Medicine
Konstantinopoulos, Panagiotis A, Karamouzis, Michalis V, Papavassiliou, Athanasios G
Molecular medicine is transforming everyday clinical practice from an empirical art to a rational ortho-molecular science. The prevailing concept in this emerging framework of molecular medicine is a...
DNA Methylation Signature Analysis: How Easy Is It to Perform?
Piperi, Christina, Farmaki, Elena, Vlastos, Fotis, Papavassiliou, Athanasios G., Martinet, Nadine
Epigenetic changes, or heritable alterations in gene function that do not affect DNA sequence, are rapidly gaining acceptance as co-conspirators in carcinogenesis. Although DNA methylation signature...