Avtandil Nanobashvili

Publication List Details

Period

2003 - 2006

Number

12

Co-Authors

Role of Neuropeptides and Neurotrophic Factors in Seizure Modulation (2003)

Nanobashvili, Avtandil

The presented thesis explores role of glial cell line derived neurotrophic factor family receptor a2 (GFRa2), as well as neuropeptide Y (NPY) and galanin and their receptors in modulation of seizure...

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

Bengzon, Johan, Kokaia, Zaal, Elmér, Eskil, Nanobashvili, Avtandil, Kokaia, Merab, Lindvall, Olle

Neuronal apoptosis was observed in the rat dentate gyrus in two experimental models of human limbic epilepsy. Five hours after one hippocampal kindling stimulation, a marked increase of in situ...

Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, ...

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse...

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

Bengzon, Johan, Kokaia, Zaal, Elmér, Eskil, Nanobashvili, Avtandil, Kokaia, Merab, Lindvall, Olle

Neuronal apoptosis was observed in the rat dentate gyrus in two experimental models of human limbic epilepsy. Five hours after one hippocampal kindling stimulation, a marked increase of in situ...

Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, ...

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse...

BDNF-induced TrkB activation down-regulates the K+–Cl− cotransporter KCC2 and impairs neuronal Cl− extrusion

Rivera, Claudio, Li, Hong, Thomas-Crusells, Judith, Lahtinen, Hannele, Viitanen, Tero, Nanobashvili, Avtandil, ...

Pathophysiological activity and various kinds of traumatic insults are known to have deleterious long-term effects on neuronal Cl− regulation, which can lead to a suppression of fast postsynaptic...