Masako Ogura, J. Christian Perez, Hae-Kyung Lee, Geidrius Dailide, Shumin Tan, ...
Geographic partitioning is postulated to foster divergence of Helicobacter pylori populations as an adaptive response to local differences in predominant host physiology. H. pylori's ability to...
Masako Ogura, Christian Perez, Peer Mittl, Hae-Kyung Lee, Geidrius Dailide, Shumin Tan, ...
Geographic partitioning is postulated to foster divergence of Helicobacter pylori populations as an adaptive response to local differences in predominant host physiology. H. pylori's ability to...
Functional Adaptation of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin (2004)
Aspholm-Hurtig, Marina, Dailide, Giedrius, Lahmann, Martina, Kalia, Awdhesh, Ilver, Dag, Roche, Niamh, ...
Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we report that more than 95% of strains that bind fucosylated blood group antigen bind A, B, and O antigens...
Feil, Edward J., Holmes, Edward C., Bessen, Debra E., Chan, Man-Suen, Day, Nicholas P. J., Enright, Mark C., ...
The identification of clones within bacterial populations is often taken as evidence for a low rate of recombination, but the validity of this inference is rarely examined. We have used statistical...
Enright, Mark C., Spratt, Brian G., Kalia, Awdhesh, Cross, John H., Bessen, Debra E.
Multilocus sequence typing (MLST) is a tool that can be used to study the molecular epidemiology and population genetic structure of microorganisms. A MLST scheme was developed for Streptococcus...
Directional Gene Movement from Human-Pathogenic to Commensal-Like Streptococci
Kalia, Awdhesh, Enright, Mark C., Spratt, Brian G., Bessen, Debra E.
Group A streptococci (GAS) are highly pathogenic for humans, and their closest genetic relatives, group C and G streptococci (GCS and GGS, respectively), are generally regarded as commensals,...
Bessen, Debra E., Kalia, Awdhesh
Streptococcus pyogenes is an important bacterial pathogen afflicting humans. A striking feature is its extraordinary biological diversity, evident in the wide range of diseases it can cause and the...
Kalia, Awdhesh, Spratt, Brian G., Enright, Mark C., Bessen, Debra E.
The throat and skin of the human host are the principal reservoirs for the bacterial pathogen Streptococcus pyogenes. The emm locus encodes structurally heterogeneous surface fibrils that play...
Kalia, Awdhesh, Bessen, Debra E.
The molecular mechanisms underlying niche adaptation in bacteria are not fully understood. Primary infection by the pathogen group A streptococcus (GAS) takes place at either the throat or the skin...
McGregor, Karen F., Spratt, Brian G., Kalia, Awdhesh, Bennett, Alicia, Bilek, Nicole, Beall, Bernard, ...
A long-term goal is to characterize the full range of genetic diversity within Streptococcus pyogenes as it exists in the world today. Since the emm locus is subject to strong diversifying selection,...
Evolutionary Dynamics of Insertion Sequences in Helicobacter pylori
Kalia, Awdhesh, Mukhopadhyay, Asish K., Dailide, Giedrius, Ito, Yoshiyki, Azuma, Takeshi, Wong, Benjamin C. Y., ...
Prokaryotic insertion sequence (IS) elements behave like parasites in terms of their ability to invade and proliferate in microbial gene pools and like symbionts when they coevolve with their...
Kersulyte, Dangeruta, Kalia, Awdhesh, Zhang, MaoJun, Lee, Hae-Kyung, Subramaniam, Dharmalingam, Kiuduliene, Levute, ...
Here we describe ISHp609 of Helicobacter pylori, a new member of the IS605 mobile element family that is novel and contains two genes whose functions are unknown, jhp960 and jhp961, in addition to...
Feil, Edward J., Holmes, Edward C., Bessen, Debra E., Chan, Man-Suen, Day, Nicholas P. J., Enright, Mark C., ...
The identification of clones within bacterial populations is often taken as evidence for a low rate of recombination, but the validity of this inference is rarely examined. We have used statistical...
Enright, Mark C., Spratt, Brian G., Kalia, Awdhesh, Cross, John H., Bessen, Debra E.
Multilocus sequence typing (MLST) is a tool that can be used to study the molecular epidemiology and population genetic structure of microorganisms. A MLST scheme was developed for Streptococcus...
Directional Gene Movement from Human-Pathogenic to Commensal-Like Streptococci
Kalia, Awdhesh, Enright, Mark C., Spratt, Brian G., Bessen, Debra E.
Group A streptococci (GAS) are highly pathogenic for humans, and their closest genetic relatives, group C and G streptococci (GCS and GGS, respectively), are generally regarded as commensals,...
Bessen, Debra E., Kalia, Awdhesh
Streptococcus pyogenes is an important bacterial pathogen afflicting humans. A striking feature is its extraordinary biological diversity, evident in the wide range of diseases it can cause and the...
Kalia, Awdhesh, Spratt, Brian G., Enright, Mark C., Bessen, Debra E.
The throat and skin of the human host are the principal reservoirs for the bacterial pathogen Streptococcus pyogenes. The emm locus encodes structurally heterogeneous surface fibrils that play...
Kalia, Awdhesh, Bessen, Debra E.
The molecular mechanisms underlying niche adaptation in bacteria are not fully understood. Primary infection by the pathogen group A streptococcus (GAS) takes place at either the throat or the skin...
McGregor, Karen F., Spratt, Brian G., Kalia, Awdhesh, Bennett, Alicia, Bilek, Nicole, Beall, Bernard, ...
A long-term goal is to characterize the full range of genetic diversity within Streptococcus pyogenes as it exists in the world today. Since the emm locus is subject to strong diversifying selection,...
Evolutionary Dynamics of Insertion Sequences in Helicobacter pylori
Kalia, Awdhesh, Mukhopadhyay, Asish K., Dailide, Giedrius, Ito, Yoshiyki, Azuma, Takeshi, Wong, Benjamin C. Y., ...
Prokaryotic insertion sequence (IS) elements behave like parasites in terms of their ability to invade and proliferate in microbial gene pools and like symbionts when they coevolve with their...
Kersulyte, Dangeruta, Kalia, Awdhesh, Zhang, MaoJun, Lee, Hae-Kyung, Subramaniam, Dharmalingam, Kiuduliene, Levute, ...
Here we describe ISHp609 of Helicobacter pylori, a new member of the IS605 mobile element family that is novel and contains two genes whose functions are unknown, jhp960 and jhp961, in addition to...
Ogura, Masako, Perez, J. Christian, Mittl, Peer R. E, Lee, Hae-Kyung, Dailide, Geidrius, Tan, Shumin, ...
Geographic partitioning is postulated to foster divergence of Helicobacter pylori populations as an adaptive response to local differences in predominant host physiology. H. pylori's ability to...