Aysegul Sahin

Publication List Details

Period

1992 - 2009

Number

52

Co-Authors

The subcellular localization of IGFBP5 affects its cell growth and migration functions in breast cancer (2009)

Akkiprik, Mustafa, Hu, Limei, Sahin, Aysegul, Hao, Xishan, Zhang, Wei

Abstract Background Insulin-like growth factor binding protein 5 (IGFBP5) has been shown to be associated with breast cancer metastasis in clinical marker studies. However, a major difficulty in...

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays (2009)

Wang, Yuker, Carlton, Victoria EH, Karlin-Neumann, George, Sapolsky, Ronald, Zhang, Li, Moorhead, Martin, ...

Abstract Background A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded...

The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis (2008)

Wang, Aijin, Arantes, Stacey, Yan, Leqin, Kiguchi, Kaoru, McArthur, Mark J, Sahin, Aysegul, ...

Abstract Background Overexpression of the bZip transcription factor, ATF3, in basal epithelial cells of transgenic mice under the control of the bovine cytokeratin-5 (CK5) promoter has previously...

Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer (2008)

Akkiprik, Mustafa, Feng, Yumei, Wang, Huamin, Chen, Kexin, Hu, Limei, Sahin, Aysegul, ...

Abstract The insulin-like growth factor axis, which has been shown to protect cells from apoptosis, plays an essential role in normal cell physiology and in cancer development. The family of...

The Vegetative Propagation Possibilities of Black Alder [Alnus glutinosa subsp. barbata (C. A. Mey.) Yalt.] by Softwood Cuttings (2006)

Sezgin Ayan, Zeki Yahyaoglu, Vildan Gercek, Aysegul Sahin, Ahmet Sivacioglu

In this study, the collecting date of softwood cuttings, rooting media, ortet age and cutting type were investigated on Alnus glutinosa subsp. barbata (C. A. Mey.) Yalt. Rooting media and cutting...

The Vegetative Propagation Possibilities of Black Alder [Alnus glutinosa subsp. barbata (C. A. Mey.) Yalt.] by Softwood Cuttings (2006)

Sezgin Ayan, Zeki Yahyaoglu, Vildan Gercek, Aysegul Sahin, Ahmet Sivacioglu

In this study, the collecting date of softwood cuttings, rooting media, ortet age and cutting type were investigated on Alnus glutinosa subsp. barbata (C. A. Mey.) Yalt. Rooting media and cutting...

Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women (2006)

Lu, Jiachun, Wei, Qingyi, Bondy, Melissa L., Li, Donghui, Brewster, Abenaa, Shete, Sanjay, ...

DNA double strand breaks (DSBs) may lead to genomic instability and cancer if unrepaired. Nijmegen breakage syndrome 1 (NBS1) protein is one of the key proteins that participate in recognition and...

Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women (2006)

Lu, Jiachun, Wei, Qingyi, Bondy, Melissa L., Li, Donghui, Brewster, Abenaa, Shete, Sanjay, ...

DNA double-strand breaks (DSBs) may lead to genomic instability and cancer if unrepaired. Nijmegen breakage syndrome 1 (NBS1) protein is one of the key proteins that participates in recognition and...

Gene expression signature of estrogen receptor α status in breast cancer (2005)

Abba, Martín C, Hu, Yuhui, Sun, Hongxia, Drake, Jeffrey A, Gaddis, Sally, Baggerly, Keith, ...

Abstract Background Estrogens are known to regulate the proliferation of breast cancer cells and to modify their phenotypic properties. Identification of estrogen-regulated genes in human breast...

Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression (2004)

Abba, Martin C, Drake, Jeffrey A, Hawkins, Kathleen A, Hu, Yuhui, Sun, Hongxia, Notcovich, Cintia, ...

Abstract Introduction Genomic and transcriptomic alterations affecting key cellular processes such us cell proliferation, differentiation and genomic stability are considered crucial for the...

Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer (2004)

Poindexter, Nancy J, Sahin, Aysegul, Hunt, Kelly K, Grimm, Elizabeth A

Abstract Introduction Sentinel lymph node (SLN) biopsy allows identification of the first lymph node into which a primary tumor drains. In breast cancer, identification of tumor cells in the SLNs is...

Unemployment insurance and the role of self-insurance (2002)

Abdulkadiroglu, Atila, Kuruscu, Burhanettin, Sahin, Aysegul

This paper employs a dynamic general equilibrium model to design and evaluate long-term unemployment insurance plans (plans that depend on workers' unemployment history) in economies with and without...

Unemployment insurance and the role of self-insurance (2002)

Abdulkadiroglu, Atila, Kuruscu, Burhanettin, Sahin, Aysegul

This paper employs a dynamic general equilibrium model to design and evaluate long-term unemployment insurance plans (plans that depend on workers' unemployment history) in economies with and without...

Altered Expression of Retinoblastoma Protein and Known Prognostic Variables in Locally Advanced Bladder Cancer (1992)

Logothetis, Christopher J., Xu, Hong-Ji, Ro, Jae Y., Hu, Shi-Xue, Sahin, Aysegul, Ordonez, Nelson, ...

Background: The clinical behavior of the tumor in patients with locally advanced bladder carcinoma is unpredictable. Current predictors of clinical behavior include depth of muscle invasion, presence...

Why Did the Average Duration of Unemployment Become So Much Longer?

Toshihiko Mukoyama, Aysegul Sahin

This paper examines the causes of the observed increase in the average unemployment duration over the past thirty years. First we analyze if changes in the demographic com- position of the U.S. labor...

Costs of Business Cycles for Unskilled Workers

Toshihiko Mukoyama, Aysegul Sahin

This paper reconsiders the cost of business cycles under market incompleteness. Primarily, we focus on the heterogeneity in the cost among different skill groups. Unskilled workers are subject to a...

Fortran code for Hansen-Imrohoroglu (1992) JPE article

Aysegul Sahin

This code replicates the results in Gary Hansen and Ayse Imrohoroglu, "The Role of Unemployment Insurance in an Economy with Liquidity Constraints and Moral Hazard", JPE 1992. Also there are...

Chromogenic In Situ Hybridization for α6β4 Integrin in Breast Cancer : Correlation with Protein Expression

Diaz, Leslie K., Zhou, Xiao, Welch, Kristin, Sahin, Aysegul, Gilcrease, Michael Z.

The α6β4 integrin is the receptor for the basement membrane protein laminin-5. Recent studies suggest that α6β4 integrin expression in invasive breast carcinomas may be a poor prognostic factor....

Unemployment insurance and the role of self-insurance

Atila Abdulkadiroglu, Burhanettin Kuruscu, Aysegul Sahin

This paper employs a dynamic general equilibrium model to design and evaluate long-term unemployment insurance plans (plans that depend on workers' unemployment history) in economies with and without...

Unemployment Insurance and the Role of Self-Insurance

Atila Abdulkadiroglu, Burhanettin Kuruscu, Aysegul Sahin

This paper employs a dynamic general equilibrium model to design and evaluate long-term unemployment insurance plans (plans that depend on workers' unemployment history) in economies with and without...

The incentive effects of higher education subsidies on student effort

Aysegul Sahin

This paper uses a game-theoretic model to analyze the disincentive effects of low-tuition policies on student effort. The model of parent and student responses to tuition subsidies is then calibrated...

Why did the average duration of unemployment become so much longer?

Toshihiko Mukoyama, Aysegul Sahin

This paper examines the causes of the observed increase in the average duration of unemployment over the past thirty years. First we analyze whether changes in the demographic composition of the U.S....

The cost of business cycles for unskilled workers

Toshihiko Mukoyama, Aysegul Sahin

This paper reconsiders the cost of business cycles under incomplete markets. Primarily, we focus on the heterogeneity in the cost of business cycles among agents with different skill levels....

On the Changing Structure of Unemployment Duration

Aysegul Sahin, Toshihiko Mukoyama

This paper examines the causes of observed increase in the duration of unemployment relative to the unemployment rate in the Post-War United States. First we analyze if changes in the demographic...

On the Welfare Effect of Cyclical Policies under Incomplete Markets and Labor Market Frictions

Aysegul Sahin, Toshihiko Mukoyama

This paper examines how policies affect people's welfare during business cycles when markets are incomplete. In particular, we analyze cyclical policies such as cyclical taxation and cyclical...

On Flexibity and Productivity

Bart Hobijn, Aysegul Sahin

We introduce a joint model of labor market search and firm size dynamics to explain the differential in labor market and productivity outcomes between the U.S. and the European Union. At the core,...

Aggregate Implications of Indivisible Labor, Incomplete Markets, and Labor Market Frictions

Per Krusell, Toshihiko Mukoyama, Richard Rogerson, Aysegul Sahin

This paper analyzes a model that features frictions, an operative labor supply margin, and incomplete markets. We first provide analytic solutions to a benchmark model that includes indivisible labor...

Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer

Akkiprik, Mustafa, Feng, Yumei, Wang, Huamin, Chen, Kexin, Hu, Limei, Sahin, Aysegul, ...

The insulin-like growth factor axis, which has been shown to protect cells from apoptosis, plays an essential role in normal cell physiology and in cancer development. The family of insulin-like...

Unemployment Dynamics in the OECD

Michael Elsby, Bart Hobijn, Aysegul Sahin

We provide a set of comparable estimates for the rates of inflow to and outflow from unemployment for fourteen OECD economies using publicly available data. We then devise a method to decompose...

Appendices for "Revisiting the Welfare Effects of Eliminating Business Cycles"

Per Krusell, Toshihiko Mukoyama, Aysegul Sahin

This paper offers several appendices for the article: the integration principle applied to the baseline model, the computational algorithm for the baseline model, calculating the welfare gain,...

Code files for "Revisiting the Welfare Effects of Eliminating Business Cycles"

Per Krusell, Toshihiko Mukoyama, Aysegul Sahin

Fortran codes to replicate results in the article. The programs are divided into two folders. One contains the two-employment-state case, and the other contains the three-employment-state case. Each...

Revisiting the Welfare Effects of Eliminating Business Cycles

Per Krusell, Toshihiko Mukoyama, Aysegul Sahin

We investigate the welfare effects of eliminating business cycles in a model with substantial consumer heterogeneity. The heterogeneity arises from uninsurable and idiosyncratic uncertainty in...

Unemployment dynamics in the OECD

Michael Elsby, Bart Hobijn, Aysegul Sahin

We provide a set of comparable estimates for the rates of inflow to and outflow from unemployment for 14 OECD economies using publicly available data. We then devise a method to decompose changes in...

A Three State Model of Worker Flows in General Equilibrium

Per Krusell, Toshihiko Mukoyama, Richard Rogerson, Aysegul Sahin

We develop a simple model featuring search frictions and a nondegenerate labor supply decision along the extensive margin. The model is a standard version of the neoclassical growth model with...

Aggregate Labor Market Outcomes: The Role of Choice and Chance

Per Krusell, Toshihiko Mukoyama, Richard Rogerson, Aysegul Sahin

Commonly used frictional models of the labor market imply that changes in frictions have large effects on steady state employment and unemployment. We use a model that features both frictions and an...

Labor-Market Matching with Precautionary Savings and Aggregate Fluctuations

Per Krusell, Toshihiko Mukoyama, Aysegul Sahin

We analyze a Bewley-Huggett-Aiyagari incomplete-markets model with labor-market frictions. Consumers are subject to idiosyncratic employment shocks against which they cannot insure directly. The...

Labor-Market Matching with Precautionary Savings and Aggregate Fluctuations

Krusell, Per, Mukoyama, Toshihiko, Sahin, Aysegul

We analyze a Bewley-Huggett-Aiyagari incomplete-markets model with labor-market frictions. Consumers are subject to idiosyncratic employment shocks against which they cannot insure directly. The...

A Three State Model of Worker Flows in General Equilibrium

Krusell, Per, Mukoyama, Toshihiko, Rogerson, Richard, Sahin, Aysegul

We develop a simple model featuring search frictions and a nondegenerate labor supply decision along the extensive margin. The model is a standard version of the neoclassical growth model with...

Aggregate Labor Market Outcomes: The Role of Choice and Chance

Krusell, Per, Mukoyama, Toshihiko, Rogerson, Richard, Sahin, Aysegul

Commonly used frictional models of the labor market imply that changes in frictions have large effects on steady state employment and unemployment. We use a model that features both frictions and an...