Bärbel Stecher, Riccardo Robbiani, Alan W. Walker, Astrid M. Westendorf, Manja Barthel, Marcus Kremer, ...
Most mucosal surfaces of the mammalian body are colonized by microbial communities (“microbiota”). A high density of commensal microbiota inhabits the intestine and shields from infection...
Type III Secretion of Salmonella enterica Serovar Typhimurium Translocated Effectors and SseFG†
Hansen-Wester, Imke, Stecher, Bärbel, Hensel, Michael
The type III secretion system (TTSS) encoded by Salmonella enterica serovar Typhimurium pathogenicity island 2 (SPI2) is employed by Salmonella enterica for interaction with host cells during the...
Analyses of the Evolutionary Distribution of Salmonella Translocated Effectors
Hansen-Wester, Imke, Stecher, Bärbel, Hensel, Michael
The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI2) translocates Salmonella translocated effectors (STE) into host cells. STE are encoded by genes outside of SPI2. The...
Hapfelmeier, Siegfried, Ehrbar, Kristin, Stecher, Bärbel, Barthel, Manja, Kremer, Marcus, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium (serovar Typhimurium) induces enterocolitis in humans and cattle. The mechanisms of enteric salmonellosis have been studied most extensively in...
InvB Is Required for Type III-Dependent Secretion of SopA in Salmonella enterica Serovar Typhimurium
Ehrbar, Kristin, Hapfelmeier, Siegfried, Stecher, Bärbel, Hardt, Wolf-Dietrich
The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA...
Stecher, Bärbel, Hapfelmeier, Siegfried, Müller, Catherine, Kremer, Marcus, Stallmach, Thomas, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium is a common cause of gastrointestinal infections. The host's innate immune system and a complex set of Salmonella virulence factors are thought to...
Stecher, Bärbel, Macpherson, Andrew J., Hapfelmeier, Siegfried, Kremer, Marcus, Stallmach, Thomas, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium is a common cause of bacterial enterocolitis. Mice are generally protected from Salmonella serovar Typhimurium colonization and enterocolitis by...
Real-time imaging of type III secretion: Salmonella SipA injection into host cells
Schlumberger, Markus C., Müller, Andreas J., Ehrbar, Kristin, Winnen, Brit, Duss, Iwan, Stecher, Bärbel, ...
Many pathogenic and symbiotic Gram-negative bacteria employ type III secretion systems to inject “effector” proteins into eukaryotic host cells. These effectors manipulate signaling pathways to...
Type III Secretion of Salmonella enterica Serovar Typhimurium Translocated Effectors and SseFG†
Hansen-Wester, Imke, Stecher, Bärbel, Hensel, Michael
The type III secretion system (TTSS) encoded by Salmonella enterica serovar Typhimurium pathogenicity island 2 (SPI2) is employed by Salmonella enterica for interaction with host cells during the...
Analyses of the Evolutionary Distribution of Salmonella Translocated Effectors
Hansen-Wester, Imke, Stecher, Bärbel, Hensel, Michael
The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI2) translocates Salmonella translocated effectors (STE) into host cells. STE are encoded by genes outside of SPI2. The...
Hapfelmeier, Siegfried, Ehrbar, Kristin, Stecher, Bärbel, Barthel, Manja, Kremer, Marcus, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium (serovar Typhimurium) induces enterocolitis in humans and cattle. The mechanisms of enteric salmonellosis have been studied most extensively in...
InvB Is Required for Type III-Dependent Secretion of SopA in Salmonella enterica Serovar Typhimurium
Ehrbar, Kristin, Hapfelmeier, Siegfried, Stecher, Bärbel, Hardt, Wolf-Dietrich
The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA...
Stecher, Bärbel, Hapfelmeier, Siegfried, Müller, Catherine, Kremer, Marcus, Stallmach, Thomas, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium is a common cause of gastrointestinal infections. The host's innate immune system and a complex set of Salmonella virulence factors are thought to...
Stecher, Bärbel, Macpherson, Andrew J., Hapfelmeier, Siegfried, Kremer, Marcus, Stallmach, Thomas, Hardt, Wolf-Dietrich
Salmonella enterica subspecies 1 serovar Typhimurium is a common cause of bacterial enterocolitis. Mice are generally protected from Salmonella serovar Typhimurium colonization and enterocolitis by...
Real-time imaging of type III secretion: Salmonella SipA injection into host cells
Schlumberger, Markus C., Müller, Andreas J., Ehrbar, Kristin, Winnen, Brit, Duss, Iwan, Stecher, Bärbel, ...
Many pathogenic and symbiotic Gram-negative bacteria employ type III secretion systems to inject “effector” proteins into eukaryotic host cells. These effectors manipulate signaling pathways to...
Stecher, Bärbel, Paesold, Günther, Barthel, Manja, Kremer, Marcus, Jantsch, Jonathan, Stallmach, Thomas, ...
Salmonella enterica subspecies 1 serovar Typhimurium is an enteric bacterial pathogen infecting a broad range of hosts. In susceptible Nramp1−/− (Slc11α1−/−) mice, serovar Typhimurium cannot...
Stecher, Bärbel, Robbiani, Riccardo, Walker, Alan W, Westendorf, Astrid M, Barthel, Manja, Kremer, Marcus, ...
Most mucosal surfaces of the mammalian body are colonized by microbial communities (“microbiota”). A high density of commensal microbiota inhabits the intestine and shields from infection...
Hapfelmeier, Siegfried, Müller, Andreas J., Stecher, Bärbel, Kaiser, Patrick, Barthel, Manja, Endt, Kathrin, ...
Intestinal dendritic cells (DCs) are believed to sample and present commensal bacteria to the gut-associated immune system to maintain immune homeostasis. How antigen sampling pathways handle...