S. D. Bouffler, B. A. Bridges, D. N. Cooper, Y. Dubrova, T. J. McMillan, J. Thacker, ...
Bouffler, S. D., Bridges, B. A., Cooper, D. N., Dubrova, Y., McMillan, T. J., Thacker, J., Wright, E. G. and Waters, R. Assessing Radiation-Associated Mutational Risk to the Germline: Repetitive DNA...
Workshop on DNA repair. (1992)
Lehmann, A.R., Hoeijmakers, J.H.J., Zeeland, A.A. Van, Backendorf, C.M.P., Bridges, B.A., Collins, A., ...
A workshop on DNA repair with emphasis on eukaryotic systems was held, under the auspices of the EC Concerted Action on DNA Repair and Cancer, at Noordwijkerhout (The Netherlands) 14-19 April 1991....
International Conference On Environmental Nitrogens : 2a. : 1977 : Edinburg, Scott, David, Bridges, B.A, Sobelds, F.H, International Mutagen Societies, European Environmental Mutagen Societies
Conference sponsored: The International Association of Environmental Mutagen Societies and the European Enviromental Mutagen Society
The tyrT locus of Escherichia coli B.
The tyrT (tRNA(1TYr)) locus of Escherichia coli B differs structurally from that of K-12 strains by the absence of 2 of 3.14 terminal repeat sequences.
Elevated mutation rate in mutT bacteria during starvation: evidence for DNA turnover?
The rate of appearance of prototrophic revertants when Escherichia coli tyrA14 (ochre) or trpA23 bacteria were incubated on plates lacking the required amino acid was greatly elevated when the...
Bates, H, Randall, S K, Rayssiguier, C, Bridges, B A, Goodman, M F, Radman, M
The induction of mutations to valine resistance and to rifampin resistance occurs after UV irradiation in bacteria carrying a deletion through the polA gene (delta polA), showing that DNA polymerase...
Bockrath, R, Ruiz-Rubio, M, Bridges, B A
Prototrophic mutants produced by UV light in Escherichia coli K-12 strains with argE3(Oc) and hisG4(Oc) defects are distinguished as backmutations and specific nonsense suppressor mutations. In...
Ruiz-Rubio, M, Woodgate, R, Bridges, B A, Herrera, G, Blanco, M
UV mutagenesis to His+ in certain recA441 lexA51 bacteria was not photoreversible, indicating that pyrimidine dimers are not target lesions. Photoreversibility was observed in recA+ lexA51 bacteria,...
Bridges, B. A., Mottershead, R. P.
A series of Escherichia coli K-12 AB1157 strains with normal and defective deoxyribonucleic acid repair capacity were more resistant to treatment with 8-methoxypsoralen (8-MOP) and near-ultraviolet...
Mutations at the gyrB locus were found to decrease the degree of supercoiling of the Escherichia coli chromosome. The effect of a gyrB mutation on the repair of ultraviolet-induced deoxyribonucleic...
Bridges, B A, Mottershead, R P, Green, M H
Escherichia coli BS-12 uvrA lon is hypersensitive to ultraviolet light. On minimal agar plates at densities in excess of about 10(7) bacteria per plate, as few as one or two photoreversible...
Bridges, B. A., Sedgwick, S. G.
Daughter-strand gaps in deoxyribonucleic acid (DNA) synthesized after exposure of excision-deficient Escherichia coli to ultraviolet light are filled during subsequent incubation in buffer, and the...
Chemostat-grown Escherichia coli showed recA+-dependent resistance to gamma radiation even though between 50 and 75% of the population possessed only a single unreplicated genome, suggesting that...
When excision-deficient Escherichia coli carrying umuC or umuD alleles were exposed to visible light several hours after ultraviolet irradiation, base-pair-substitution mutations were induced in...
Strains of Escherichia coli carrying the mutY mutation lack a mismatch correction glycosylase that removes adenines from various mismatch situations. In growing bacteria, 8-oxoguanine-adenine...
Waters, M D, Stack, H F, Jackson, M A, Bridges, B A
For more than a decade, mutagenicity tests have had a clearly defined role in the identification of potential human mutagens and an ancillary role in the identification of potential human...
When 3 x 10(8) bacteria of the Escherichia coli tyrA14(oc) leu308(am) strain WU3610 are plated on glucose salts agar supplemented with leucine only, colonies of slow-growing Tyr+ suppressor mutants...
The tyrT locus of Escherichia coli B.
The tyrT (tRNA(1TYr)) locus of Escherichia coli B differs structurally from that of K-12 strains by the absence of 2 of 3.14 terminal repeat sequences.
Elevated mutation rate in mutT bacteria during starvation: evidence for DNA turnover?
The rate of appearance of prototrophic revertants when Escherichia coli tyrA14 (ochre) or trpA23 bacteria were incubated on plates lacking the required amino acid was greatly elevated when the...
Bates, H, Randall, S K, Rayssiguier, C, Bridges, B A, Goodman, M F, Radman, M
The induction of mutations to valine resistance and to rifampin resistance occurs after UV irradiation in bacteria carrying a deletion through the polA gene (delta polA), showing that DNA polymerase...
Bockrath, R, Ruiz-Rubio, M, Bridges, B A
Prototrophic mutants produced by UV light in Escherichia coli K-12 strains with argE3(Oc) and hisG4(Oc) defects are distinguished as backmutations and specific nonsense suppressor mutations. In...
Ruiz-Rubio, M, Woodgate, R, Bridges, B A, Herrera, G, Blanco, M
UV mutagenesis to His+ in certain recA441 lexA51 bacteria was not photoreversible, indicating that pyrimidine dimers are not target lesions. Photoreversibility was observed in recA+ lexA51 bacteria,...
Bridges, B. A., Mottershead, R. P.
A series of Escherichia coli K-12 AB1157 strains with normal and defective deoxyribonucleic acid repair capacity were more resistant to treatment with 8-methoxypsoralen (8-MOP) and near-ultraviolet...
Mutations at the gyrB locus were found to decrease the degree of supercoiling of the Escherichia coli chromosome. The effect of a gyrB mutation on the repair of ultraviolet-induced deoxyribonucleic...
Bridges, B A, Mottershead, R P, Green, M H
Escherichia coli BS-12 uvrA lon is hypersensitive to ultraviolet light. On minimal agar plates at densities in excess of about 10(7) bacteria per plate, as few as one or two photoreversible...
Bridges, B. A., Sedgwick, S. G.
Daughter-strand gaps in deoxyribonucleic acid (DNA) synthesized after exposure of excision-deficient Escherichia coli to ultraviolet light are filled during subsequent incubation in buffer, and the...
Chemostat-grown Escherichia coli showed recA+-dependent resistance to gamma radiation even though between 50 and 75% of the population possessed only a single unreplicated genome, suggesting that...
When excision-deficient Escherichia coli carrying umuC or umuD alleles were exposed to visible light several hours after ultraviolet irradiation, base-pair-substitution mutations were induced in...
Strains of Escherichia coli carrying the mutY mutation lack a mismatch correction glycosylase that removes adenines from various mismatch situations. In growing bacteria, 8-oxoguanine-adenine...
When 3 x 10(8) bacteria of the Escherichia coli tyrA14(oc) leu308(am) strain WU3610 are plated on glucose salts agar supplemented with leucine only, colonies of slow-growing Tyr+ suppressor mutants...
Waters, M D, Stack, H F, Jackson, M A, Bridges, B A
For more than a decade, mutagenicity tests have had a clearly defined role in the identification of potential human mutagens and an ancillary role in the identification of potential human...
Hypermutation in bacteria and other cellular systems.
A temporary state of hypermutation can in principle arise through an increase in the rate of polymerase errors (which may or may not be triggered by template damage) and/or through abrogation of...