B. Birren

Publication List Details

Period

2001 - 2009

Number

16

Co-Authors

Sequencing the Phytophthora infestans Genome: Preliminary Studies (2004)

O'Neill, K., Zody, M.C., Karlsson, E., Govers, F., Weide, R.L., ...

Phytophthora infestans, the causal agent of Late Blight of potato, is arguably the most significant biotic threat to global food security. An annotated P. infestans genome sequence is a critically...

Initial sequencing and analysis of the human genome (2001)

Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, ...

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and...

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

Shizuya, H, Birren, B, Kim, U J, Mancino, V, Slepak, T, Tachiiri, Y, ...

A bacterial cloning system for mapping and analysis of complex genomes has been developed. The BAC system (for bacterial artificial chromosome) is based on Escherichia coli and its single-copy...

Transformation of Escherichia coli with large DNA molecules by electroporation.

Sheng, Y, Mancino, V, Birren, B

We have examined bacterial electroporation with a specific interest in the transformation of large DNA, i.e. molecules > 100 kb. We have used DNA from bacterial artificial chromosomes (BACs) ranging...

Stable propagation of cosmid sized human DNA inserts in an F factor based vector.

Kim, U J, Shizuya, H, De Jong, P J, Birren, B, Simon, M I

Instability of complex mammalian genomic DNA inserts is commonplace in cosmid libraries constructed in conventional multicopy vectors. To develop a means to construct stable libraries, we have...

Rapid pulsed field separation of DNA molecules up to 250 kb.

Birren, B, Lai, E

Pulsed field gel electrophoresis (PFGE) is capable of resolving a wide size range of DNA molecules which would all co-migrate in conventional agarose gels. We describe pulsed field gel conditions...

Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: evidence for an extended control region.

Pfeifer, D, Kist, R, Dewar, K, Devon, K, Lander, E S, Birren, B, ...

Campomelic dysplasia (CD), a skeletal malformation syndrome with or without XY sex reversal, is usually caused by mutations within the SOX9 gene on distal 17q. Several CD translocation and inversion...

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

Shizuya, H, Birren, B, Kim, U J, Mancino, V, Slepak, T, Tachiiri, Y, ...

A bacterial cloning system for mapping and analysis of complex genomes has been developed. The BAC system (for bacterial artificial chromosome) is based on Escherichia coli and its single-copy...

Transformation of Escherichia coli with large DNA molecules by electroporation.

Sheng, Y, Mancino, V, Birren, B

We have examined bacterial electroporation with a specific interest in the transformation of large DNA, i.e. molecules > 100 kb. We have used DNA from bacterial artificial chromosomes (BACs) ranging...

Stable propagation of cosmid sized human DNA inserts in an F factor based vector.

Kim, U J, Shizuya, H, De Jong, P J, Birren, B, Simon, M I

Instability of complex mammalian genomic DNA inserts is commonplace in cosmid libraries constructed in conventional multicopy vectors. To develop a means to construct stable libraries, we have...

Rapid pulsed field separation of DNA molecules up to 250 kb.

Birren, B, Lai, E

Pulsed field gel electrophoresis (PFGE) is capable of resolving a wide size range of DNA molecules which would all co-migrate in conventional agarose gels. We describe pulsed field gel conditions...

Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: evidence for an extended control region.

Pfeifer, D, Kist, R, Dewar, K, Devon, K, Lander, E S, Birren, B, ...

Campomelic dysplasia (CD), a skeletal malformation syndrome with or without XY sex reversal, is usually caused by mutations within the SOX9 gene on distal 17q. Several CD translocation and inversion...