Disruption of iron homeostasis increases phosphine toxicity in Caenorhabditis elegans (2007)
Cha'on, U., Valmas, N., Collins, P. J., Reilly, P. E. B., Hammock, B. D., Ebert, P. R.
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is...
Disruption of iron homeostasis increases phosphine toxicity in Caenorhabditis elegans (2007)
Cha'on, U., Valmas, N., Collins, P. J., Reilly, P. E. B., Hammock, B. D., Ebert, P. R.
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is...
Disruption of iron homeostasis increases phosphine toxicity in caenorhabditis elegans (2007)
Cha'on, U., Valmas, N., Collins, P.J., Reilly, P.E.B., Hammock, B.D., Ebert, P.R.
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is...
Disruption of iron homeostasis increases phosphine toxicity in caenorhabditis elegans (2007)
Cha'on, U., Valmas, N., Collins, P.J., Reilly, P.E.B., Hammock, B.D., Ebert, P.R.
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is...
Disruption of iron homeostasis increases phosphine toxicity in caenorhabditis elegans (2007)
Cha'on, U., Valmas, N., Collins, P.J., Reilly, P.E.B., Hammock, B.D., Ebert, P.R.
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is...
Fisslthaler, B, Suzuki, M, ...
TRPV4 is a broadly expressed Ca2+-permeable cation channel in the vanilloid subfamily of transient receptor potential channels. TRPV4 gates in response to a large variety of stimuli, including cell...
Pokreisz, Peter; U0032789, Vermeersch, Pieter; U0035259, Szelid, Z, Falck, J. R, Hammock, B. D, Fleming, I, ...
Waterfield, N., Kamita, S. G., Hammock, B. D., Ffrench-Constant, R.
The genome of the insect pathogen Photorhabdus luminescens strain TT01 contains numerous genes predicting toxins and proteases. Within the P. luminescens TT01 genome, the products of two loci, plu...
Stok, J E, Goloshchapov, A, Song, C, Wheelock, C E, Derbel, MBH, Morisseau, C, ...
Carboxylesterases are enzymes that catalyze the hydrolysis of ester and amide moieties. These enzymes have an active site that is composed of a nucleophile (Set), a base (His), and an acid (Glu) that...
Immunochemical determination of dioxins in sediment and serum samples (2004)
Nichkova, M, Park, E K, Koivunen, M E, Kamita, S G, Gee, S J, Chuang, J, ...
Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are considered highly toxic contaminants and the environmental and biological monitoring of these compounds is of...
Stok, J E, Huang, H Z, Jones, P D, Wheelock, C E, Morisseau, C, Hammock, B D
Carboxylesterases are enzymes that catalyze the hydrolysis of a wide range of ester-containing endogenous and xenobiotic compounds. Although the use of pyrethroids is increasing, the specific enzymes...
Chiappe, C, Leandri, E, Lucchesi, S, Pieraccini, D, Hammock, B D, Morisseau, C
Soluble epoxide hydrolase (sEH) was shown to catalyze hydrolysis of epoxides using the ionic liquids (ILs) [bmim][PF6], [bmim][N(Tf)(2)], and [bmim][BF4] (where bmim = 1-butyl-3-methylimidazolium,...
Fluorescence quenching competitive immunoassay in micro droplets (2003)
Feng, J, Shan, G M, Hammock, B D, Kennedy, Ian M
A fluorescence quenching competitive immunoassay in micro droplets was applied to the sensitive detection of the pyrethroid insecticide, esfenvalerate. Laser induced fluorescence from rhodamine dye...
Bonning, B.C., Ward, V.K., Vlak, J.M., Hammock, B.D.
The insecticidal efficacy of baculoviruses can be enhanced by engineering the viral genome to express proteins that disrupt the physiology of the host insect. Here we describe the development of a...
Eldridge, R, O'Reilly, D R, Hammock, B D, Miller, L K
Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...
Wie, S I, Andrews, R E, Hammock, B D, Faust, R M, Bulla, L A
An enzyme-linked immunosorbent assay was used to detect and quantitate the parasporal crystal toxins of Bacillus thuringiensis subspp. kurstaki and israelensis. The assay method described is...
The crystal delta-endotoxin of Bacillus thuringiensis subsp. israelensis is less toxic to larvae of Anopheles freeborni than to larvae of Aedes aegypti. However, when solubilized crystal was used,...
Epoxide hydrolase from liver cytosol (cEH) of both normal and clofibrate-treated mice can be bioselectively adsorbed onto an affinity column prepared from epoxy-activated Sepharose and...
Evaluation of fish models of soluble epoxide hydrolase inhibition.
Newman, J W, Denton, D L, Morisseau, C, Koger, C S, Wheelock, C E, Hinton, D E, ...
Substituted ureas and carbamates are mechanistic inhibitors of the soluble epoxide hydrolase (sEH). We screened a set of chemicals containing these functionalities in larval fathead minnow (Pimphales...
Eldridge, R, O'Reilly, D R, Hammock, B D, Miller, L K
Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...
Wie, S I, Andrews, R E, Hammock, B D, Faust, R M, Bulla, L A
An enzyme-linked immunosorbent assay was used to detect and quantitate the parasporal crystal toxins of Bacillus thuringiensis subspp. kurstaki and israelensis. The assay method described is...
The crystal delta-endotoxin of Bacillus thuringiensis subsp. israelensis is less toxic to larvae of Anopheles freeborni than to larvae of Aedes aegypti. However, when solubilized crystal was used,...
Epoxide hydrolase from liver cytosol (cEH) of both normal and clofibrate-treated mice can be bioselectively adsorbed onto an affinity column prepared from epoxy-activated Sepharose and...
Evaluation of fish models of soluble epoxide hydrolase inhibition.
Newman, J W, Denton, D L, Morisseau, C, Koger, C S, Wheelock, C E, Hinton, D E, ...
Substituted ureas and carbamates are mechanistic inhibitors of the soluble epoxide hydrolase (sEH). We screened a set of chemicals containing these functionalities in larval fathead minnow (Pimphales...