From Computational Biophysics to Systems Biology (CBSB07), (2009)
B. Fischer, W. Wenzel, Jan Meinke, Ipan Mohanty, ...
Proceedings of the NIC Workshop 2007,
B. Fischer, H. Merlitz, K. Fukuzawa, W. Wenzel, ...
published in
H. Sánchez, B. Fischer, H. Merlitz, W. Wenzel, Jan H. Meinke, ...
published in
Scott, M., Stones, J., Payne, N., Cook, T. M., Fischer, B., Bogod, D., ...
High throughput in-silico screening with flexible receptors. (2009)
Kokh, D., Perez-Sanchez, H., Fischer, B., Wenzel, W.
53rd Biophysical Society's Annual Meeting, Boston, Mass., February 28 - March 4, 2009
High throughput in-silico screening against flexible protein receptors. (2009)
Perez-Sanchez, H., Fischer, B., Kokh, D., Merlitz, H., Wenzel, W.
Accelrys User Group Meeting, San Diego, Calif., February 18-20, 2009
Comparisons of the PTB primary clocks with TAI in 1999 (2008)
A. Bauch, B. Fischer, T. Heindorff, P. Hetzel, G. Petit, R. Schröder, ...
metrologia
Towards Reuse with ``Feature-Oriented Event-B'' (2008)
Poppleton, M., Fischer, B., Franklin, C., Gondal, A., Snook, C., Sorge, J.
Event-B [MAV:05] is a language for the formal specification and verification of reactive systems. The language and its RODIN toolkit represent a leading model-based technology for formal software...
A. Bauch, B. Fischer, T. Heindorff, R. Schröder
Abstract. The paper describes the current performance of the primary clock CS1 of the Physikalisch-Technische Bundesanstalt (PTB). The clock employs a thermal atomic beam and magnetic state...
ESCHER’s Complex Objects: A Demonstration of Simplicity (2008)
B. Fischer, J. Thamm, L. Wegner, S. Wilke, C. Zirkelbach
ESCHER is a visual database editor for the object-relational data model. Here, we describe the essential features of ESCHER and what is demonstrated at this conference with our prototype. Readers are...
Analysis and Optimization of the Flex-Screen Docking Approach Using DUD Benchmarking Database (2008)
D. Kokh, B. Fischer, W. Wenzel, Jan Meinke, Ipan Mohanty, ...
Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made or distributed for profit or commercial advantage and...
Role of cathepsins in blastocyst hatching in the golden hamster (2008)
Sireesha, GV, Mason, RW, Hassanein, M, Tonack, S, Santos, Navarrete A, Fischer, B, ...
The mammalian embryo is encased in a glycoproteinaceous coat, the zona pellucida (ZP) during preimplantation development.Prior to implantation, the blastocyst must undergo ‘hatching’ or ZP...
Objective Condition Assessment of Sewer Systems (2008)
Abstract Apart from guaranteeing the proper function of sewer systems in day to day operation, sewer system operators also must ensure that the substance of this valuable public asset is preserved...
Bartels, T., Fischer, B., Krueger, P., Koch, E., Ryll, M., Krautwald-Junghanns, M.E.
The routine culling of the male offspring of hybrid layer type chickens is met Summary with increasing public disapproval for both ethical and legal reasons. Until now practice-oriented methods for...
Role of cathepsins in blastocyst hatching in the golden hamster (2008)
Sireesha, GV, Mason, RW, Hassanein, M, Tonack, S, Santos, Navarrete A, Fischer, B, ...
The mammalian embryo is encased in a glycoproteinaceous coat, the zona pellucida (ZP) during preimplantation development.Prior to implantation, the blastocyst must undergo ‘hatching’ or ZP...
Poznyakovskiy, A.A., Zahnert, T., Kalaidzidis, Y., Schmidt, R., Fischer, B., Baumgart, J., ...
The modeling of the mechanical process of hearing requires an accurate geometrical model of the inner ear (cochlea). The purpose of this study was the creation of a 3-D model of the fluid chambers of...
Hightech-Materialien für die Elektronik von morgen (2008)
Jank, M.P., Bauer, A.J., Fischer, B., Slama, A., Potinecke, T.
Role of cathepsins in blastocyst hatching in the golden hamster (2008)
Sireesha, G.V., Mason, R.W., Hassanein, M., Tonack, S., Navarrete Santos, A., Fischer, B., ...
The mammalian embryo is encased in a glycoproteinaceous coat, the zona pellucida (ZP) during preimplantation development. Prior to implantation, the blastocyst must undergo ‘hatching’ or ZP...
High throughput in silico screening with receptor flexibility. (2008)
Kokh, D., Sanchez, H., Fischer, B.
Gordon Research Conf.Computational Chemistry : New Computational Tools For 21st Century Chemistry, South Hadley, Mass., July 26 - August 1, 2008
High throughput in-silico screening against flexible protein receptors. (2008)
Sanchez, H., Fischer, B., Merlitz, H., Wenzel, W.
Hansmann, U.H.E. [Hrsg.]
High throughput in-silico screening with flexible receptors. (2008)
Kokh, D., Sanchez, H., Fischer, B., Wenzel, W.
Latest Advances in Drug Discovery Informatics, Hyderabad, IND, December 19-20, 2008
Fischer, B., Fukuzawa, K., Wenzel, W.
Proteins: Structure, Function, and Bioinformatics, 70(2008) S.1264-73
High throughput in-silico screening with flexible receptors. (2008)
Kokh, D., Sanchez, H., Fischer, B., Wenzel, W.
2008 Accelrys European User Group Meeting, Divonne-les-Bains, F, December 9-12, 2008
Untersuchung der biologischen Aktivität von aggregierenden und zellpenetrierenden Peptiden. (2008)
Diplomarbeit, Universität Karlsruhe 2007
Non-equilibrium coherence dynamics in one-dimensional Bose gases (2007)
Hofferberth, S., Lesanovsky, I., Fischer, B., Schumm, T., Schmiedmayer, J.
Low-dimensional systems are beautiful examples of many-body quantum physics. For one-dimensional systems the Luttinger liquid approach provides insight into universal properties. Much is known of the...
A fast online hit verification method for the single ion hit system at GSI (2007)
Du, G., Fischer, B., Barberet, P., Heiss, M.
For a single ion hit facility built to irradiate specific targets inside biological cells, it is necessary to prove that the ions hit the selected targets reliably because the ion hits usually cannot...
Reflections on Sir Henk van der Vorst. (2007)
Brandts, J.H., Fischer, B., Wathen, A.
About SIAM News, the newsjournal of the applied mathematics community! SIAM News offers: technical overview articles written by experts in a wide range of disciplines reports of progress and...
Reflections on Sir Henk van der Vorst. (2007)
Brandts, J.H., Fischer, B., Wathen, A.
About SIAM News, the newsjournal of the applied mathematics community! SIAM News offers: technical overview articles written by experts in a wide range of disciplines reports of progress and...
Virtual-screening with continuous receptor flexibility. (2007)
Fischer, B., Merlitz, H., Wenzel, W.
51st Biophysical Society Annual Meeting, Baltimore, Md., March 3-7, 2007
Perez Sanchez, H.E., Fischer, B., Merlitz, H., Wenzel, W.
Workshop on Computer Simulation and Theory of Macromolecules, Hünfeld, April 20-22, 2007
Perez Sanchez, H.E., Fischer, B., Merlitz, H., Wenzel, W.
Workshop on Computer Simulation and Theory of Macromolecules, Hünfeld, April 20-21, 2007
High Throughput Simulations Methoden zum Protein-Liganden Docking. (2007)
Vortr.: Universität Dortmund, 19.April 2007
Accuracy of binding mode prediction with a cascadic stochastic tunneling method. (2007)
Fischer, B., Basili, S., Merlitz, H., Wenzel, W.
Proteins: Structure, Function and Bioinformatics, 68(2007) S.195-204
Simultane Beobachtung von Vertikalwind und Regenraten. (2007)
Peters, G., Fischer, B., Brümmer, B., Lange, I., Vogt, S.
Deutsch-Österreichisch-Schweizerische Meteorologen-Tagung (DACH 2007), Hamburg, 10.-14.September 2007
High troughput in-silico screening with flexible receptors. (2007)
Perez Sanchez, H.E., Fischer, B., Merlitz, H., Wenzel, W.
Workshop 'Methods of Molecular Simulation', Heidelberg, September 24-26, 2007
High througput in-silico screening against flexible protein receptors. (2007)
Perez Sanchez, H.E., Fischer, B., Merlitz, H., Wenzel, W.
From Genomes to In Silico and Back : Meeting of the Spanish Systems Biology Network (REBS), Murcia, E, November 15-16, 2007
Ultracold atoms in radio-frequency-dressed potentials beyond the rotating wave approximation (2006)
Hofferberth, S., Fischer, B., Schumm, T., Schmiedmayer, J., Lesanovsky, I.
We study dressed Bose-Einstein condensates in an atom chip radio-frequency trap. We show that in this system sufficiently strong dressing can be achieved to cause the widely used rotating wave...
Radio-frequency dressed state potentials for neutral atoms (2006)
Hofferberth, S., Lesanovsky, I., Fischer, B., Verdu, J., Schmiedmayer, J.
Potentials for atoms can be created by external fields acting on properties like magnetic moment, charge, polarizability, or by oscillating fields which couple internal states. The most prominent...
Bürgstein, H., Eckardt, J., Fischer, B.
In 2005 German hospitals for the first time published legally specified quality reports. A group of practitioners from the German health service analysed assessments of this public information tool...
A FAST ONLINE HIT VERIFICATION METHOD FOR THE SINGLE ION HIT SYSTEM AT GSI (2006)
Du, G., Fischer, B., Barberet, P., Heiss, M.
For a single ion hit facility built to irradiate specific targets inside biological cells, it is necessary to prove that the ions hit the selected targets reliably because the ion hits usually cannot...
High troughput in-silico screening against flexible protein receptors. (2006)
Fischer, B., Merlitz, H., Wenzel, W.
Vortr.: Sanofi-Aventis AG, Frankfurt, 1.Februar 2006
High throughput in-silico screening of large ligand databases for rational drug design. (2006)
Merlitz, H., Fischer, B., Wenzel, W.
Starikov, E.B. [Hrsg.]
Modeling of industrial bulk crystal growth - State of the art and challenges (2005)
Fischer, B., Friedrich, J., Jung, T., Hainke, M., Dagner, J., Fühner, T., ...
Gorenflo, S., Hinkov, I., Lambrecht, A., Fischer, B., Hoffmann, M., Helm, H., ...
Ein Terahertz-Time-Domain-Spektroskopie- (THz-TDS-) System mit elektrooptischem Detektor auf der Basis von ZnTe wird vorgestellt. Als Laserquelle dient ein Ti:S a-Laser, der Laserpulse mit einer...
Evaluation and case studies of FlexScreen (a Docking program with receptor-flexibility). (2005)
Workshop on Computer Simulation and Theory of Macromolecules, Hünfeld, April 22-24, 2005
Increasing diversity in in-silico screening with target flexibility. (2005)
Fischer, B., Merlitz, H., Wenzel, W.
1st Internat.Symp.on Computational Life Science (CompLife'05), Konstanz, September 25-27, 2005
Increasing diversity in in-silico screening with target flexibility. (2005)
Fischer, B., Merlitz, H., Wenzel, W.
Berthold, M.R. [Hrsg.]
Biomolecular structure prediction stochastic optimization methods. (2005)
Schug, A., Fischer, B., Verma, A., Merlitz, H., Wenzel, W., Schoen, G.
Advanced Engineering Materials, 7(2005) S. 1005-09
Some new electron-affine polymers for organic photovoltaics (2004)
Krüger, H., Janietz, S., Sainova, D., Wedel, A., Fischer, B.
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency (2003)
Grimbacher, B., Hutloff, A., Schlesier, M., Glocker, E., Warnatz, K., Dräger, R., ...
No genetic defect is known to cause common variable immunodeficiency (CVID), a heterogeneous human disorder leading to adult-onset panhypogammaglobulinemia. In a search for CVID candidate proteins,...
High performance computer codes and their application to optimize crystal growth processes (2003)
Czarny, O., Droll, P., El Ganaoui, M., Fischer, B., Hainke, M., Kadinski, L., ...
Polyurethanes with covalent attached fluorescent dyes as deep red emitting materials (2003)
Janietz, S., Krüger, H., Wedel, A., Fischer, B.
A unusual way is presented to obtain a new class of deep red emitting polymers. Polyurethanes with covalently attached fluorescent dyes were developed. The DCM-dye seems to be a favorable candidate...
Polymers with covalently attached dyes - materials for OLEDs and photovoltaics? (2003)
Krüger, H., Janietz, S., Wedel, A., Fischer, B.
An unusual way is presented to obtain a new class of deep red emitting polyurethanes with covalently attached fluorescent dyes. The DCM-dye seems to be a favourable candidate but we had to introduce...
Krueger, H., Fischer, B., Janietz, S., Wedel, A., Wahl, J.
WO2003018711 A UPAB: 20030723 NOVELTY - New polymer dyes are based on a 4-dicyanomethylene-pyran compound (I), which has a 4-N-(polymer)-amino-styryl substituent in the 2- and/or 6-position(s), in...
Yin, S.G., Wedel, A., Janietz, S., Krueger, H., Sainova, D., Arlt, K., ...
A novel copolymer. Poly{N-[(2-ethyl)-hexyl]-2,7(8)-phenothianinylenevinylene-co-2,5-bis[2,2 '-didodecyloxy-(p-phenylenevinylene)]1,3,4-oxadiazole} (P-PT-OXA-EH) exhibiting high decomposing...
Free-form registration using mutual information and curvature regularization (2003)
D’Agostino E., Modersitzki J., Maes F., Vandermeulen D., Fischer B., Suetens P., ''Free-form registration using mutual information and curvature regularization'', Lecture notes in computer science,...
Involvement of TP53 in Apoptosis Induced in Human Lymphoblastoid Cells by Fast Neutrons (2002)
D. Coelho, B. Fischer, V. Holl, G. M. Jung, P. Dufour, J. P. Bergerat, ...
Coelho, D., Fischer, B., Holl, V., Jung, G. M., Denis, J. M., Dufour, P., Bergerat, J. P., Gueulette, J. and Bischoff, P. L. Involvement of TP53 in Apoptosis Induced in Human Lymphoblastoid Cells by...
Doney, A., Fischer, B., Frew, D., Cumming, A., Flavell, D.M., World, M., ...
Background: Variation at the PPARG locus may influence susceptibility to type 2 diabetes and related traits. The Pro12Ala polymorphism may modulate receptor activity and is associated with protection...
Heroin-assisted treatment as a response to the public health problem of opiate dependence (2002)
Fischer, B., Rehm, J., Kirst, M., Casas, M.E., Hall, W., Krausz, M.Z., ...
Melt flow and species transport in µg-gradient freeze growth of germanium (2002)
Pätzold, O., Fischer, B., Cröll, A.
The result of a mug-experiment on the Gradient-Freeze growth of Ge:Zn with doping from the vapour phase shows a homogeneous distribution of the zinc in the melt, indicating the dominating role of a...
Heroin-assisted treatment as a response to the public health problem of opiate dependence (2002)
Fischer, B, Rehm, J, Kirst, M, Casas, M, Hall, W, Krausz, M, ...
Injection drug use (involving the injection of illicit opiates) poses serious public health problems in many countries. Research has indicated that injection drug users are at higher risk for...
Heroin-assisted treatment as a response to the public health problem of opiate dependence (2002)
Fischer, B, Rehm, J, Kirst, M, Casas, M, Hall, W, Krausz, M, ...
Injection drug use (involving the injection of illicit opiates) poses serious public health problems in many countries. Research has indicated that injection drug users are at higher risk for...
The Modula-2 Proving System MOPS (2000)
Th. Kaiser, Th. Kaiser, B. Fischer, B. Fischer, W. Struckmann, W. Struckmann, ...
In this report we describe the MOdula-2 Proving System MOPS. It is a Hoare-calculus based program verication system for a large subset of the programming language Modula-2 which uses VDM-SL as...
Dynamics of surface migration in the weak corrugation regime (2000)
Barth, J. V., Brune, H., Fischer, B., Weckesser, J., Kern, K.
We report a systematic study for metal-on-metal surface migration in the weak corrugation regime, i.e., with migration barriers falling below approximate to 100 meV. The migration characteristics are...
Untersuchungen zum mechanischen Verhalten von FeCrAl-Legierungen (1999)
Lange, J.H., Brede, M., Klöwer, J., Fischer, B., Spindler, S., Wagner, H., ...
Nucleation kinetics on inhomogeneous substrates: Al/Au(111) (1999)
Fischer, B., Brune, H., Barth, J. V., Fricke, A., Kern, K.
We report a quantitative atomic scale study of nucleation kinetics on an inhomogeneous substrate. Our model system, Al/Au(111)-(root 3 x 22), reveals a distinct nucleation transition due to the...
Strain relief via island ramification in submonolayer heteroepitaxy (1998)
Muller, B., Nedelmann, L. P., Fischer, B., Brune, H., Barth, J. V., Kern, K., ...
The mechanisms of strain relief in submonolayer heteroepitaxy of Cu/Ni(100) are studied using variable temperature scanning tunneling microscopy and high resolution low energy electron diffraction....
Island shape transition in heteroepitaxial metal growth on square lattices (1998)
Muller, B., Nedelmann, L., Fischer, B., Brune, H., Barth, J. V., Kern, K.
A novel mechanism for ramified island growth in the initial stages of metal heteroepitaxy is reported. Scanning tunneling microscopy measurements reveal that copper islands on Ni(100), as they grow...
Transport analysis for polycrystalline silicon solar cells on glass substrates. (1997)
Brendel, R., Bergmann, R., Fischer, B., Krinke, J., Plieninger, R., Rau, U., ...
Jones, T. T. C., Adams, J. M., Ageladarakis, P., AliArshad, S., Alper, B., Altmann, H., ...
Planned experiments in the Joint European Torus [Plasma Physics and Controlled Fusion Research, Proceedings, 13th International Conference, Washington, D.C., 1990 (International Atomic Energy Agency,...
Latest JET results in deuterium and deuterium-tritium plasmas (1997)
Adams, J. M., Ageladarakis, P., Arshad, S. A., Alper, B., Altmann, H., Andrew, P., ...
All major JET systems have been fully commissioned for D-T and the DTE1 series of experiments has started with the D-T fuel mixture and operating conditions foreseen for ITER. In the area of ITER...
The Convergence Of Iterative Solution Methods For Symmetric And Indefinite Linear Systems (1997)
A.J. Wathen, B. Fischer, D.J. Silvester
this paper we concentrate on convergence estimates for miminum residual iteration applied to a linear system Ax = b, (so that A represents the preconditioned coefficient matrix if preconditioning is...
Nucleation and growth of Cu/Ni(100): A variable temperature STM study (1997)
Muller, B., Nedelmann, L., Fischer, B., Brune, H., Kern, K.
A detailed study of the nucleation and growth of Cu on Ni(100) as a function of substrate temperature and deposition rate by variable temperature STM is reported. By the quantitative analysis of the...
Submonolayer nucleation and growth of copper on Ni(100) (1997)
Muller, B., Nedelmann, L., Fischer, B., Brune, H., Kern, K.
Island densities and island sizes can be varied or even tailored by choice of external parameters in molecular beam epitaxy, i.e.: by the choice of substrate temperature. deposition rate, and...
Fischer, B., Selmi, L., Ghetti, A., Sangiorgi, E.
Measured electron injection probabilities (PJN) into to the gate oxide of MOS structures [1] are presented for both liquid nitrogen and room temperature. For the first time PJN has been measured for...
Fischer, B., Selmi, L., Ghetti, A., Sangiorgi, E.
Measured electron injection probabilities (PJN) into to the gate oxide of MOS structures [1] are presented for both liquid nitrogen and room temperature. For the first time PJN has been measured for...
Fischer, B., Selmi, L., Ghetti, A., Sangiorgi, E.
Measured electron injection probabilities (PJN) into to the gate oxide of MOS structures [1] are presented for both liquid nitrogen and room temperature. For the first time PJN has been measured for...
B. Fischer, A. Ramage, D. J. Silvester, A. J. Wathen
. In this work we consider the design of robust and efficient finite element approximation methods for solving advection-diffusion equations. Specifically, we consider the stabilisation of discrete...
JET results with the new pumped divertor and implications for ITER (1995)
Adams, J. M., Ageladarakis, P., Alper, B., Altmann, H., Andrew, P., AliArshad, S., ...
This paper presents an overview of results of the 1994/95 experimental campaign on JET with the new pumped divertor and draws implications for ITER in the areas of detached and radiative divertor...
First Results with the Modified Jet - the Jet Team (1994)
Adams, J. M., Agarici, Y., Ageladarakis, P., Alper, B., Altmann, H., Andrew, P., ...
JET was extensively modified in the 1992/93 shutdown. The new pumped divertor and many new systems were brought into operation early in 1994. Operations have progressed to 4MA plasma current and,...
Deduction-Based Software Component Retrieval (1994)
B. Fischer, M. Kievernagel, G. Snelting, Tu Braunschweig, Abteilung Fur Softwaretechnologie
We present a retrieval approach which allows pre- and postconditions of software components to be used as search keys. A component qualifies, if it has a weaker precondition and a stronger...
VCR: A VDM-based software component retrieval tool (1994)
B. Fischer, B. Fischer, M. Kievernagel, M. Kievernagel, W. Struckmann, W. Struckmann, ...
We present a tool which allows implicit VDM specifications to be used as search keys for the retrieval of software components. A preprocessing phase utilizes signature matching to filter promising...
Flammhemmende Bindemittel zur Herstellung von Basismaterial fuer Leiterplatten (1991)
Bauer, M., Born, E., Keusch, S., Frenzel, H., Fischer, B., Haase, A., ...
The invention relates to flame-retardant binding agents for the production of base material (laminates) of high quality for printed circuit boards. The binding agents represent a single-component...
KARNATH, H. O., SCHENKEL, P., FISCHER, B.
SUMMARY The present study examines which egocentric coordinate system determines the border between the disturbed ‘contralateral’ and the normal ‘ipsilateral’ side in patients with...
The structure of the pyridine complex of dicylopentadienylcadmium (1987)
Fischer, B., Boersma, J., Smeets, W.J.J., Spek, A.L.
The structure of the pyridine complex of dicyclopentadienylcadmium is described; the two cyclopentadienyl rings are both monohapto-bonded to cadmium.
NEW STUDY AND APPLICATION OF PHASE CONJUGATION WITH PHOTOREFRACTIVE CRYSTALS (1983)
A theoretical and experimental study of four-wave mixing in photorefractive crystals like SBN and BaTiO3 will be presented. A detailed theoretical analysis of the beam coupling as well as new...
NEW STUDY AND APPLICATION OF PHASE CONJUGATION WITH PHOTOREFRACTIVE CRYSTALS (1983)
A theoretical and experimental study of four-wave mixing in photorefractive crystals like SBN and BaTiO3 will be presented. A detailed theoretical analysis of the beam coupling as well as new...
NEW STUDY AND APPLICATION OF PHASE CONJUGATION WITH PHOTOREFRACTIVE CRYSTALS (1983)
A theoretical and experimental study of four-wave mixing in photorefractive crystals like SBN and BaTiO3 will be presented. A detailed theoretical analysis of the beam coupling as well as new...
Tulapurkar, M E, Laubinger, W, Nahum, V, Fischer, B, Reiser, G
P2Y-nucleotide receptors represent important targets for drug development. The lack of stable and receptor specific agonists, however, has prevented successful therapeutic applications. A novel...
Boyer, J. L., O'Tuel, J. W., Fischer, B., Jacobson, K. A., Harden, T. K.
1. Analogues of adenine nucleotides inhibited beta-adrenoceptor-stimulated cyclic AMP accumulation in C6 rat glioma cells with a pharmacological selectivity consistent with that for involvement of a...
Boyer, J. L., Siddiqi, S., Fischer, B., Romero-Avila, T., Jacobson, K. A., Harden, T. K.
1. A series of chain-extended 2-thioether derivatives of adenosine monophosphate were synthesized and tested as agonists for activation of the phospholipase C-linked P2Y-purinoceptor of turkey...
Bo, X., Fischer, B., Maillard, M., Jacobson, K. A., Burnstock, G.
1. Radioligand binding assays have been used to determine the affinities of a series of ATP derivatives with modifications of the polyphosphate chain, adenine and ribose moieties of the ATP molecule...
Müller, B, Fischer, B, Kreutz, W
The microenvironment within solid tumours has often been shown to exhibit an acidic local pH. In recent studies we could demonstrate that an acidic extracellular pH (pHe) inhibits the non-major...