In vitro antifungal and fungicidal spectra of a new pradimicin derivative, BMS-181184.
Fung-Tomc, J C, Minassian, B, Huczko, E, Kolek, B, Bonner, D P, Kessler, R E
A new pradimicin derivative, BMS-181184, was compared with amphotericin B and fluconazole against 249 strains from 35 fungal species to determine its antifungal spectrum. Antifungal testing was...
In vitro activity of BMS-181139, a new carbapenem with potent antipseudomonal activity.
Kessler, R E, Fung-Tomc, J, Kolek, B, Minassian, B, Huczko, E, Gradelski, E, ...
The in vitro activities of the carbapenem BMS-181139 were determined in comparison with those of imipenem, meropenem, ciprofloxacin, ceftriaxone, and vancomycin. BMS-181139 was the most active...
Fung-Tomc, J C, Gradelski, E, Kolek, B, Minassian, B, Pucci, M, Kessler, R E, ...
The broad antipseudomonal spectrum of the carbapenem BMS-181139 includes clinical strains and laboratory mutants of Pseudomonas aeruginosa that are resistant to imipenem. Unlike other known...
Fung-Tomc, J C, Huczko, E, Banville, J, Ménard, M, Kolek, B, Gradelski, E, ...
A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As...
Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides.
Fung-Tomc, J C, Huczko, E, Stickle, T, Minassian, B, Kolek, B, Denbleyker, K, ...
Thirteen oral cephems (cefprozil, loracarbef, cefaclor, cefuroxime axetil, cefpodoxime proxetil, cefetamet pivoxil, cefixime, cefdinir, cefadroxil, cephradine, cephalexin, cefatrizine, and...
Antibacterial activity of BMS-180680, a new catechol-containing monobactam.
Fung-Tomc, J, Bush, K, Minassian, B, Kolek, B, Flamm, R, Gradelski, E, ...
The in vitro activities of a new catechol-containing monobactam, BMS-180680 (SQ 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin,...
Mamber, S W, Kolek, B, Brookshire, K W, Bonner, D P, Fung-Tomc, J
Eight quinolones were examined for their bacterial mutagenicity in the Ames Salmonella TA102 assay and for their effects in other bacterial genotoxicity assays. In the quantitative Ames plate...
Fung-Tomc, J, Kolek, B, Bonner, D P
The effects of ciprofloxacin on the rates of development of low-level resistance to other antibiotics were determined in vitro. Three methicillin-resistant Staphylococcus aureus and two Pseudomonas...
Fung-Tomc, J, Huczko, E, Kolek, B, Thater, C, Kessler, R E
The in vitro activity of cefepime was compared with those of ceftazidime, cefotaxime, and cefpirome against aminoglycoside-resistant gram-negative bacteria. Cefepime was the most active...
In vitro antifungal and fungicidal spectra of a new pradimicin derivative, BMS-181184.
Fung-Tomc, J C, Minassian, B, Huczko, E, Kolek, B, Bonner, D P, Kessler, R E
A new pradimicin derivative, BMS-181184, was compared with amphotericin B and fluconazole against 249 strains from 35 fungal species to determine its antifungal spectrum. Antifungal testing was...
In vitro activity of BMS-181139, a new carbapenem with potent antipseudomonal activity.
Kessler, R E, Fung-Tomc, J, Kolek, B, Minassian, B, Huczko, E, Gradelski, E, ...
The in vitro activities of the carbapenem BMS-181139 were determined in comparison with those of imipenem, meropenem, ciprofloxacin, ceftriaxone, and vancomycin. BMS-181139 was the most active...
Fung-Tomc, J C, Gradelski, E, Kolek, B, Minassian, B, Pucci, M, Kessler, R E, ...
The broad antipseudomonal spectrum of the carbapenem BMS-181139 includes clinical strains and laboratory mutants of Pseudomonas aeruginosa that are resistant to imipenem. Unlike other known...
Fung-Tomc, J C, Huczko, E, Banville, J, Ménard, M, Kolek, B, Gradelski, E, ...
A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As...
Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides.
Fung-Tomc, J C, Huczko, E, Stickle, T, Minassian, B, Kolek, B, Denbleyker, K, ...
Thirteen oral cephems (cefprozil, loracarbef, cefaclor, cefuroxime axetil, cefpodoxime proxetil, cefetamet pivoxil, cefixime, cefdinir, cefadroxil, cephradine, cephalexin, cefatrizine, and...
Antibacterial activity of BMS-180680, a new catechol-containing monobactam.
Fung-Tomc, J, Bush, K, Minassian, B, Kolek, B, Flamm, R, Gradelski, E, ...
The in vitro activities of a new catechol-containing monobactam, BMS-180680 (SQ 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin,...
Mamber, S W, Kolek, B, Brookshire, K W, Bonner, D P, Fung-Tomc, J
Eight quinolones were examined for their bacterial mutagenicity in the Ames Salmonella TA102 assay and for their effects in other bacterial genotoxicity assays. In the quantitative Ames plate...
Fung-Tomc, J, Kolek, B, Bonner, D P
The effects of ciprofloxacin on the rates of development of low-level resistance to other antibiotics were determined in vitro. Three methicillin-resistant Staphylococcus aureus and two Pseudomonas...
Fung-Tomc, J, Huczko, E, Kolek, B, Thater, C, Kessler, R E
The in vitro activity of cefepime was compared with those of ceftazidime, cefotaxime, and cefpirome against aminoglycoside-resistant gram-negative bacteria. Cefepime was the most active...