Sobrado, J, Moldawer, L L, Bistrian, B R, Dinarello, C A, Blackburn, G L
Many of the metabolic sequelae to infection and inflammation, such as fever, trace mineral redistribution, skeletal muscle catabolism, and the acute-phase protein response, are mediated by leukocytic...
Flores, E A, Bistrian, B R, Pomposelli, J J, Dinarello, C A, Blackburn, G L, Istfan, N W
To improve our understanding of the metabolic role of cytokines in protein wasting, we estimated the rates of protein synthesis and degradation in muscle and liver tissues in intact rats treated with...
Klein, S, Young, V R, Blackburn, G L, Bistrian, B R, Wolfe, R R
Data obtained in vitro suggest that the ability to mobilize fat decreases with age. We determined lipolytic rates in vivo in normal weight young adult (22-33 yr) and elderly (65-77 yr) subjects using...
Metabolic effects of very low calorie weight reduction diets.
Hoffer, L J, Bistrian, B R, Young, V R, Blackburn, G L, Matthews, D E
A randomized comparison trial of two very low calorie weight reduction diets was carried out for 5 or 8 wk in 17 healthy obese women. One diet provided 1.5 g protein/kg ideal body weight; the other...
Pomposelli, J J, Palombo, J D, Hamawy, K J, Bistrian, B R, Blackburn, G L, Moldawer, L L
Previous studies have reported that use of a flooding dose of radiolabelled amino acid is a more precise technique than the constant infusion of tracer quantities for determining rates of protein...
Monoacetoacetin and protein metabolism during parenteral nutrition in burned rats.
Maiz, A, Moldawer, L L, Bistrian, B R, Birkhahn, R H, Long, C L, Blackburn, G L
The effect of intravenous infusion of monoacetoacetin (glycerol monoacetoacetate) as a non-protein energy source was evaluated in burned rats. During 3 days of parenteral nutrition, in which animals...
Moldawer, L L, Kawamura, I, Bistrian, B R, Blackburn, G L
1. Rates of appearance and oxidation of plasma L-leucine, L-phenylalanine and L-tyrosine, as well as conversion of plasma phenylalanine into plasma tyrosine, were determined in 90-120 g rats after...
Babineau, T J, Swails Bollinger, W, Forse, R A, Bistrian, B R
OBJECTIVE: This study was designed to identify the unique metabolic characteristics of patients undergoing cardiopulmonary bypass (CPB) surgery who require postoperative parenteral nutrition. SUMMARY...
Kenler, A S, Swails, W S, Driscoll, D F, DeMichele, S J, Daley, B, Babineau, T J, ...
OBJECTIVES: The authors compared the safety, gastrointestinal tolerance, and clinical efficacy of feeding an enteral diet containing a fish oil/medium-chain triglyceride structured lipid (FOSL-HN)...
Central venous catheterization for parenteral nutrition.
Padberg, F T, Ruggiero, J, Blackburn, G L, Bistrian, B R
To define the risks associated with central venous catheterization for total parenteral nutrition (TPN) 3291 patient days of this therapy, delivered by an established nutrition support team, were...
Teo, T C, DeMichele, S J, Selleck, K M, Babayan, V K, Blackburn, G L, Bistrian, B R
The effects of enteral feeding with safflower oil or a structured lipid (SL) derived from 60% medium-chain triglyceride (MCT) and 40% fish oil (MCT/fish oil) on protein and energy metabolism were...
Pomposelli, J J, Flores, E A, Blackburn, G L, Zeisel, S H, Bistrian, B R
The effect of 6 weeks dietary lipid manipulation on the acute physiologic response to 7-hour continuous endotoxin infusion in guinea pigs was examined. One diet was enriched with N-3 fatty acids,...
Palgi, A, Read, J L, Greenberg, I, Hoefer, M A, Bistrian, B R, Blackburn, G L
Six hundred sixty-eight obese outpatients, 71 per cent (+/- 34) in excess of ideal weight, were enrolled in a multidisciplinary weight control program. The major components of the program included...
Sobrado, J, Moldawer, L L, Bistrian, B R, Dinarello, C A, Blackburn, G L
Many of the metabolic sequelae to infection and inflammation, such as fever, trace mineral redistribution, skeletal muscle catabolism, and the acute-phase protein response, are mediated by leukocytic...
Flores, E A, Bistrian, B R, Pomposelli, J J, Dinarello, C A, Blackburn, G L, Istfan, N W
To improve our understanding of the metabolic role of cytokines in protein wasting, we estimated the rates of protein synthesis and degradation in muscle and liver tissues in intact rats treated with...
Klein, S, Young, V R, Blackburn, G L, Bistrian, B R, Wolfe, R R
Data obtained in vitro suggest that the ability to mobilize fat decreases with age. We determined lipolytic rates in vivo in normal weight young adult (22-33 yr) and elderly (65-77 yr) subjects using...
Metabolic effects of very low calorie weight reduction diets.
Hoffer, L J, Bistrian, B R, Young, V R, Blackburn, G L, Matthews, D E
A randomized comparison trial of two very low calorie weight reduction diets was carried out for 5 or 8 wk in 17 healthy obese women. One diet provided 1.5 g protein/kg ideal body weight; the other...
Pomposelli, J J, Palombo, J D, Hamawy, K J, Bistrian, B R, Blackburn, G L, Moldawer, L L
Previous studies have reported that use of a flooding dose of radiolabelled amino acid is a more precise technique than the constant infusion of tracer quantities for determining rates of protein...
Monoacetoacetin and protein metabolism during parenteral nutrition in burned rats.
Maiz, A, Moldawer, L L, Bistrian, B R, Birkhahn, R H, Long, C L, Blackburn, G L
The effect of intravenous infusion of monoacetoacetin (glycerol monoacetoacetate) as a non-protein energy source was evaluated in burned rats. During 3 days of parenteral nutrition, in which animals...
Moldawer, L L, Kawamura, I, Bistrian, B R, Blackburn, G L
1. Rates of appearance and oxidation of plasma L-leucine, L-phenylalanine and L-tyrosine, as well as conversion of plasma phenylalanine into plasma tyrosine, were determined in 90-120 g rats after...
Babineau, T J, Swails Bollinger, W, Forse, R A, Bistrian, B R
OBJECTIVE: This study was designed to identify the unique metabolic characteristics of patients undergoing cardiopulmonary bypass (CPB) surgery who require postoperative parenteral nutrition. SUMMARY...
Kenler, A S, Swails, W S, Driscoll, D F, DeMichele, S J, Daley, B, Babineau, T J, ...
OBJECTIVES: The authors compared the safety, gastrointestinal tolerance, and clinical efficacy of feeding an enteral diet containing a fish oil/medium-chain triglyceride structured lipid (FOSL-HN)...
Central venous catheterization for parenteral nutrition.
Padberg, F T, Ruggiero, J, Blackburn, G L, Bistrian, B R
To define the risks associated with central venous catheterization for total parenteral nutrition (TPN) 3291 patient days of this therapy, delivered by an established nutrition support team, were...
Teo, T C, DeMichele, S J, Selleck, K M, Babayan, V K, Blackburn, G L, Bistrian, B R
The effects of enteral feeding with safflower oil or a structured lipid (SL) derived from 60% medium-chain triglyceride (MCT) and 40% fish oil (MCT/fish oil) on protein and energy metabolism were...
Pomposelli, J J, Flores, E A, Blackburn, G L, Zeisel, S H, Bistrian, B R
The effect of 6 weeks dietary lipid manipulation on the acute physiologic response to 7-hour continuous endotoxin infusion in guinea pigs was examined. One diet was enriched with N-3 fatty acids,...
Palgi, A, Read, J L, Greenberg, I, Hoefer, M A, Bistrian, B R, Blackburn, G L
Six hundred sixty-eight obese outpatients, 71 per cent (+/- 34) in excess of ideal weight, were enrolled in a multidisciplinary weight control program. The major components of the program included...