B. Toye

Publication List Details

Period

2005 - 2005

Number

26

Co-Authors

Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitis (2005)

Proulx, N., Fréchette, D., Toye, B., Chan, J., Kravcik, S.

Background: Bacterial meningitis continues to cause high mortality. Few studies address the possible association between this mortality and antibiotic administration delays. Aim: To determine...

Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitis (2005)

Proulx, N., Fréchette, D., Toye, B., Chan, J., Kravcik, S.

Background: Bacterial meningitis continues to cause high mortality. Few studies address the possible association between this mortality and antibiotic administration delays. Aim: To determine...

Alteration of the carbohydrate binding specificity of verotoxins from Gal alpha 1-4Gal to GalNAc beta 1-3Gal alpha 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit.

Tyrrell, G J, Ramotar, K, Toye, B, Boyd, B, Lingwood, C A, Brunton, J L

Verotoxin 1 (VT-1) and Shiga-like toxin II (SLT-II) bind to the glycosphingolipid (GSL), globotriaosylceramide (Gb3), whereas pig edema disease toxin (VTE) binds to globotetraosylceramide (Gb4) and...

Inhibition of PCR in Genital and Urine Specimens Submitted for Chlamydia trachomatis Testing

Toye, B., Woods, W., Bobrowska, M., Ramotar, K.

We determined the frequency of PCR inhibition in genital and urine specimens submitted for Chlamydia trachomatis testing using the internal control DNA provided with the COBAS AMPLICOR C. trachomatis...

Diagnosis of Chlamydia trachomatis infections in asymptomatic men and women by PCR assay.

Toye, B, Peeling, R W, Jessamine, P, Claman, P, Gemmill, I

A PCR assay was evaluated for its ability to detect genital chlamydial infection in asymptomatic men and women. Urethral swab specimens were collected from 472 men for culture and PCR assay, and...

Clinical and epidemiological significance of enterococci intrinsically resistant to vancomycin (possessing the vanC genotype)

Toye, B, Shymanski, J, Bobrowska, M, Woods, W, Ramotar, K

Constitutive low-level vancomycin resistance is found intrinsically in certain enterococcal species and is encoded by vanC ligase genes. These intrinsically vancomycin-resistant enterococci (VRE)...

Risk factors for acquiring ampicillin-resistant enterococci and clinical outcomes at a Canadian tertiary-care hospital.

McCarthy, A E, Victor, G, Ramotar, K, Toye, B

The number of ampicillin-resistant enterococci (ARE) was noted to be increased at our teaching hospital. To determine the risk factors for acquiring this organism and to compare clinical outcomes,...

Broth microdilution testing of Haemophilus influenzae with haemophilus test medium versus lysed horse blood broth. Canadian Haemophilus Study Group.

Scriver, S R, Low, D E, Simor, A E, Toye, B, McGeer, A, Jaeger, R

Broth microdilution testing of 702 community-acquired isolates of Haemophilus influenzae from across Canada was performed with both Mueller-Hinton broth supplemented with 3% lysed horse blood broth...

Immunologic characterization of a cloned fragment containing the species-specific epitope from the major outer membrane protein of Chlamydia trachomatis.

Toye, B, Zhong, G M, Peeling, R, Brunham, R C

A 183-bp fragment encoding variable domain IV (VD IV) of Chlamydia trachomatis serovar B major outer membrane protein (MOMP) (amino acids 273 to 333) and containing the species-specific epitope was...

Prevalence and Mechanisms of Erythromycin Resistance in Group A and Group B Streptococcus: Implications for Reporting Susceptibility Results

Desjardins, M., Delgaty, K. L., Ramotar, K., Seetaram, C., Toye, B.

Increased rates of erythromycin resistance among group B Streptococcus (GBS) and group A Streptococcus (GAS) have been reported. Cross-resistance to clindamycin may be present, depending on the...

Evaluation of the IDI-MRSA Assay for Detection of Methicillin-Resistant Staphylococcus aureus from Nasal and Rectal Specimens Pooled in a Selective Broth

Desjardins, M., Guibord, Christiane, Lalonde, B., Toye, B., Ramotar, K.

Rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) by PCR can be performed directly from nasal specimens with the IDI-MRSA assay. To improve the efficiency of screening, we...

Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth.

Claman, P, Toye, B, Peeling, R W, Jessamine, P, Belcher, J

OBJECTIVE: To determine whether serologic evidence of Chlamydia trachomatis during pregnancy is a risk factor for preterm delivery (before 37 weeks' gestation). DESIGN: Chart review. SETTING:...

Alteration of the carbohydrate binding specificity of verotoxins from Gal alpha 1-4Gal to GalNAc beta 1-3Gal alpha 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit.

Tyrrell, G J, Ramotar, K, Toye, B, Boyd, B, Lingwood, C A, Brunton, J L

Verotoxin 1 (VT-1) and Shiga-like toxin II (SLT-II) bind to the glycosphingolipid (GSL), globotriaosylceramide (Gb3), whereas pig edema disease toxin (VTE) binds to globotetraosylceramide (Gb4) and...

Inhibition of PCR in Genital and Urine Specimens Submitted for Chlamydia trachomatis Testing

Toye, B., Woods, W., Bobrowska, M., Ramotar, K.

We determined the frequency of PCR inhibition in genital and urine specimens submitted for Chlamydia trachomatis testing using the internal control DNA provided with the COBAS AMPLICOR C. trachomatis...

Diagnosis of Chlamydia trachomatis infections in asymptomatic men and women by PCR assay.

Toye, B, Peeling, R W, Jessamine, P, Claman, P, Gemmill, I

A PCR assay was evaluated for its ability to detect genital chlamydial infection in asymptomatic men and women. Urethral swab specimens were collected from 472 men for culture and PCR assay, and...

Clinical and epidemiological significance of enterococci intrinsically resistant to vancomycin (possessing the vanC genotype)

Toye, B, Shymanski, J, Bobrowska, M, Woods, W, Ramotar, K

Constitutive low-level vancomycin resistance is found intrinsically in certain enterococcal species and is encoded by vanC ligase genes. These intrinsically vancomycin-resistant enterococci (VRE)...

Risk factors for acquiring ampicillin-resistant enterococci and clinical outcomes at a Canadian tertiary-care hospital.

McCarthy, A E, Victor, G, Ramotar, K, Toye, B

The number of ampicillin-resistant enterococci (ARE) was noted to be increased at our teaching hospital. To determine the risk factors for acquiring this organism and to compare clinical outcomes,...

Broth microdilution testing of Haemophilus influenzae with haemophilus test medium versus lysed horse blood broth. Canadian Haemophilus Study Group.

Scriver, S R, Low, D E, Simor, A E, Toye, B, McGeer, A, Jaeger, R

Broth microdilution testing of 702 community-acquired isolates of Haemophilus influenzae from across Canada was performed with both Mueller-Hinton broth supplemented with 3% lysed horse blood broth...

Immunologic characterization of a cloned fragment containing the species-specific epitope from the major outer membrane protein of Chlamydia trachomatis.

Toye, B, Zhong, G M, Peeling, R, Brunham, R C

A 183-bp fragment encoding variable domain IV (VD IV) of Chlamydia trachomatis serovar B major outer membrane protein (MOMP) (amino acids 273 to 333) and containing the species-specific epitope was...

Prevalence and Mechanisms of Erythromycin Resistance in Group A and Group B Streptococcus: Implications for Reporting Susceptibility Results

Desjardins, M., Delgaty, K. L., Ramotar, K., Seetaram, C., Toye, B.

Increased rates of erythromycin resistance among group B Streptococcus (GBS) and group A Streptococcus (GAS) have been reported. Cross-resistance to clindamycin may be present, depending on the...

Evaluation of the IDI-MRSA Assay for Detection of Methicillin-Resistant Staphylococcus aureus from Nasal and Rectal Specimens Pooled in a Selective Broth

Desjardins, M., Guibord, Christiane, Lalonde, B., Toye, B., Ramotar, K.

Rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) by PCR can be performed directly from nasal specimens with the IDI-MRSA assay. To improve the efficiency of screening, we...

Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth.

Claman, P, Toye, B, Peeling, R W, Jessamine, P, Belcher, J

OBJECTIVE: To determine whether serologic evidence of Chlamydia trachomatis during pregnancy is a risk factor for preterm delivery (before 37 weeks' gestation). DESIGN: Chart review. SETTING:...

Polymicrobial tenosynovitis with Pasteurella multocida and other Gram negative bacilli after a Siberian tiger bite

Isotalo, P, Edgar, D, Toye, B

Mammalian bites present a considerable clinical problem because they are often associated with bacterial infections. Pasteurella multocida is a microorganism that commonly infects both canine and...

Pooling of urine specimens for PCR testing: a cost saving strategy for Chlamydia trachomatis control programmes

Peeling, R. W., Toye, B., Jessamine, P., Gemmill, I.

OBJECTIVES: To evaluate pooling of first catch urine (FCU) specimens as a cost effective strategy for chlamydia testing. METHODS: Mock specimens were pooled with and without dilution to determine...