B. van Triest

Publication List Details

Period

2000 - 2000

Number

2

Co-Authors

Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors (2000)

Van Triest, B., Pinedo, H. M., Giaccone, G., Peters, G. J.

Thymidylate synthase (TS) is an essential enzyme for the de novo synthesis of thymidylate and subsequently DNA synthesis. TS has been used as a target for cancer chemotherapy in the development of...