Barbara H. Minshew

Effect of clindamycin on growth and haemolysin production by Escherichia coli (1983)

Boe, Nina M., Dellinger, E. Patchen, Minshew, Barbara H.

The effect of clindamycin on growth and haemolysin production by four strains of Escherichia coli was tested. Clindamycin MICs were >256 mg/l for all strains. Clindamycin concentrations of 16-256...

Mutational Enzymatic Resistance of Enterobacter Species to Beta-Lactam Antibiotics

Lampe, Mary F., Allan, Barbara J., Minshew, Barbara H., Sherris, John C.

Mutants with enhanced β-lactam resistance were selected from strains of Enterobacter cloacae and E. aerogenes by using three antibiotics. High-level β-lactamase-producing mutants had similar...

Cation Components of Mueller-Hinton Agar Affecting Testing of Pseudomonas aeruginosa Susceptibility to Gentamicin

Kenny, Margaret A., Pollock, Helen M., Minshew, Barbara H., Casillas, Edmundo, Schoenknecht, Fritz D.

Seven lots of Mueller-Hinton agar were examined for calcium and magnesium contents and their distribution in pools or compartments. Gel disruption and centrifugation yielded the soluble cations,...

Common Plasmid Specifying Tobramycin Resistance Found in Two Enteric Bacteria Isolated from Burn Patients

Elwell, Lynn P., Inamine, Julia M., Minshew, Barbara H.

Tobramycin-resistant burn wound isolates of Klebsiella pneumoniae and Enterobacter cloacae, together with Escherichia coli K-12 transconjugants from these two strains, were examined for plasmid...

Effect of Different Lots of Mueller-Hinton Agar on the Interpretation of the Gentamicin Susceptibility of Pseudomonas aeruginosa

Pollock, Helen M., Minshew, Barbara H., Kenny, Margaret A., Schoenknecht, Fritz D.

Population distributions and quality control data for strains of Pseudomonas aeruginosa tested for gentamicin susceptibility on six lots of Mueller-Hinton agar were analyzed. The lots of agar were...

Comparison of a Radioimmunoassay with an Enzymatic Assay for Gentamicin

Minshew, Barbara H., Holmes, Randall K., Baxter, Charles R.

A radioimmunoassay and an enzymatic assay for gentamicin have been compared. The correlation coefficient for results of gentamicin assays performed by the two methods with 45 serum specimens was...

Inhibition of Acetylating Activity in an Enzymatic Assay for Aminoglycoside Antibiotics

Minshew, Barbara H., Swanzy, Susan R., Schoenknecht, Fritz D.

The radioenzymatic technique using aminoglycoside-6′-acetyltransferase is suitable for determining serum concentrations of aminoglycoside antibiotics that have a 6′-amino group. Standard curves...

Emergence in a Burn Center of Populations of Bacteria Resistant to Gentamicin, Tobramycin, and Amikacin: Evidence for the Need for Changes in Zone Diameter Interpretative Standards

Minshew, Barbara H., Pollock, Helen M., Schoenknecht, Fritz D., Sherris, John C.

From July 1974 through June 1976, a number of isolates of Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa from the Burn Center exhibited a shift to smaller zone diameters with...

Transduction of Tetracycline Resistance in Staphylococcus epidermidis

Minshew, Barbara H., Rosenblum, E. D.

Fourteen Staphylococcus epidermidis strains were biotyped according to the scheme of Baird-Parker and tested for their sensitivities to S. epidermidis typing phages. Tetracycline-susceptible strains...

Plasmid for Tetracycline Resistance in Staphylococcus epidermidis

Minshew, Barbara H., Rosenblum, E. D.

A plasmid determining tetracycline resistance was demonstrated for Staphylococcus epidermidis. Tetracycline resistance was spontaneously lost from a S. epidermidis strain at a frequency of

Resistance of Pseudomonas aeruginosa to Gentamicin and Related Aminoglycoside Antibiotics

Holmes, Randall K., Minshew, Barbara H., Gould, Kenneth, Sanford, Jay P.

This study was undertaken to investigate biochemical, genetic, and epidemiological aspects of resistance to aminoglycoside antibiotics among 650 consecutive isolates of Pseudomonas aeruginosa from...

Transferrable Resistance to Tobramycin in Klebsiella pneumoniae and Enterobacter cloacae Associated with Enzymatic Acetylation of Tobramycin

Minshew, Barbara H., Holmes, Randall K., Sanford, Jay P., Baxter, Charles R.

Among gram-negative bacilli isolated from burn wound cultures, some strains of Enterobacteriaceae were resistant to tobramycin (minimal inhibitory concentration [MIC]≥ 20 μg/ml) but susceptible to...

Mutational Enzymatic Resistance of Enterobacter Species to Beta-Lactam Antibiotics

Lampe, Mary F., Allan, Barbara J., Minshew, Barbara H., Sherris, John C.

Mutants with enhanced β-lactam resistance were selected from strains of Enterobacter cloacae and E. aerogenes by using three antibiotics. High-level β-lactamase-producing mutants had similar...

Cation Components of Mueller-Hinton Agar Affecting Testing of Pseudomonas aeruginosa Susceptibility to Gentamicin

Kenny, Margaret A., Pollock, Helen M., Minshew, Barbara H., Casillas, Edmundo, Schoenknecht, Fritz D.

Seven lots of Mueller-Hinton agar were examined for calcium and magnesium contents and their distribution in pools or compartments. Gel disruption and centrifugation yielded the soluble cations,...

Common Plasmid Specifying Tobramycin Resistance Found in Two Enteric Bacteria Isolated from Burn Patients

Elwell, Lynn P., Inamine, Julia M., Minshew, Barbara H.

Tobramycin-resistant burn wound isolates of Klebsiella pneumoniae and Enterobacter cloacae, together with Escherichia coli K-12 transconjugants from these two strains, were examined for plasmid...

Effect of Different Lots of Mueller-Hinton Agar on the Interpretation of the Gentamicin Susceptibility of Pseudomonas aeruginosa

Pollock, Helen M., Minshew, Barbara H., Kenny, Margaret A., Schoenknecht, Fritz D.

Population distributions and quality control data for strains of Pseudomonas aeruginosa tested for gentamicin susceptibility on six lots of Mueller-Hinton agar were analyzed. The lots of agar were...

Comparison of a Radioimmunoassay with an Enzymatic Assay for Gentamicin

Minshew, Barbara H., Holmes, Randall K., Baxter, Charles R.

A radioimmunoassay and an enzymatic assay for gentamicin have been compared. The correlation coefficient for results of gentamicin assays performed by the two methods with 45 serum specimens was...

Inhibition of Acetylating Activity in an Enzymatic Assay for Aminoglycoside Antibiotics

Minshew, Barbara H., Swanzy, Susan R., Schoenknecht, Fritz D.

The radioenzymatic technique using aminoglycoside-6′-acetyltransferase is suitable for determining serum concentrations of aminoglycoside antibiotics that have a 6′-amino group. Standard curves...

Emergence in a Burn Center of Populations of Bacteria Resistant to Gentamicin, Tobramycin, and Amikacin: Evidence for the Need for Changes in Zone Diameter Interpretative Standards

Minshew, Barbara H., Pollock, Helen M., Schoenknecht, Fritz D., Sherris, John C.

From July 1974 through June 1976, a number of isolates of Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa from the Burn Center exhibited a shift to smaller zone diameters with...

Transduction of Tetracycline Resistance in Staphylococcus epidermidis

Minshew, Barbara H., Rosenblum, E. D.

Fourteen Staphylococcus epidermidis strains were biotyped according to the scheme of Baird-Parker and tested for their sensitivities to S. epidermidis typing phages. Tetracycline-susceptible strains...

Plasmid for Tetracycline Resistance in Staphylococcus epidermidis

Minshew, Barbara H., Rosenblum, E. D.

A plasmid determining tetracycline resistance was demonstrated for Staphylococcus epidermidis. Tetracycline resistance was spontaneously lost from a S. epidermidis strain at a frequency of

Resistance of Pseudomonas aeruginosa to Gentamicin and Related Aminoglycoside Antibiotics

Holmes, Randall K., Minshew, Barbara H., Gould, Kenneth, Sanford, Jay P.

This study was undertaken to investigate biochemical, genetic, and epidemiological aspects of resistance to aminoglycoside antibiotics among 650 consecutive isolates of Pseudomonas aeruginosa from...

Transferrable Resistance to Tobramycin in Klebsiella pneumoniae and Enterobacter cloacae Associated with Enzymatic Acetylation of Tobramycin

Minshew, Barbara H., Holmes, Randall K., Sanford, Jay P., Baxter, Charles R.

Among gram-negative bacilli isolated from burn wound cultures, some strains of Enterobacteriaceae were resistant to tobramycin (minimal inhibitory concentration [MIC]≥ 20 μg/ml) but susceptible to...