Barbara Jaruga

Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS

Hong, Feng, Jaruga, Barbara, Kim, Won Ho, Radaeva, Svetlana, El-Assal, Osama N., Tian, Zhigang, ...

T cell–mediated fulminant hepatitis is a life-threatening event for which the underlying mechanism is not fully understood. Injection of concanavalin A (Con A) into mice recapitulates the...

Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.

Radaeva, Svetlana, Jaruga, Barbara, Kim, Won-Ho, Heller, Theo, Liang, T Jake, Gao, Bin

IFN-gamma (interferon-gamma) modulates IFN-alpha therapy in chronic hepatitis C infection; however, the underlying mechanism remains unclear. Here we demonstrate that long-term (3-6 days) but not...

Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS

Hong, Feng, Jaruga, Barbara, Kim, Won Ho, Radaeva, Svetlana, El-Assal, Osama N., Tian, Zhigang, ...

T cell–mediated fulminant hepatitis is a life-threatening event for which the underlying mechanism is not fully understood. Injection of concanavalin A (Con A) into mice recapitulates the...

Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.

Radaeva, Svetlana, Jaruga, Barbara, Kim, Won-Ho, Heller, Theo, Liang, T Jake, Gao, Bin

IFN-gamma (interferon-gamma) modulates IFN-alpha therapy in chronic hepatitis C infection; however, the underlying mechanism remains unclear. Here we demonstrate that long-term (3-6 days) but not...