Su, Wan-Lin, Modrek, Barmak, GuhaThakurta, Debraj, Edwards, Stephen, Shah, Jyoti K, Kulkarni, Amit V, ...
Abstract Background Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing,...
Resch, Alissa, Xing, Yi, Alekseyenko, Alexander, Modrek, Barmak, Lee, Christopher
Recently there has been much interest in assessing the role of alternative splicing in evolution. We have sought to measure functional selection pressure on alternatively spliced single‐exon...
ASAP: the Alternative Splicing Annotation Project (2003)
Christopher Lee, Levan Atanelov, Barmak Modrek, Yi Xing
Recently, genomics analyses have demonstrated that alternative splicing is widespread in mammalian genomes (30–60 % of genes reported to have multiple isoforms), and maybe one of their most...
ASAP: the Alternative Splicing Annotation Project (2003)
Lee, Christopher, Atanelov, Levan, Modrek, Barmak, Xing, Yi
Recently, genomics analyses have demonstrated that alternative splicing is widespread in mammalian genomes (30–60% of genes reported to have multiple isoforms), and may be one of their most...
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome (2002)
Xu, Qiang, Modrek, Barmak, Lee, Christopher
We have developed an automated method for discovering tissue‐specific regulation of alternative splicing through a genome‐wide analysis of expressed sequence tags (ESTs). Using this...
Genome-wide detection of alternative splicing in expressed sequences of human genes (2001)
Modrek, Barmak, Resch, Alissa, Grasso, Catherine, Lee, Christopher
We have identified 6201 alternative splice relationships in human genes, through a genome-wide analysis of expressed sequence tags (ESTs). Starting with ∼2.1 million human mRNA and EST sequences,...
Genome-wide detection of alternative splicing in expressed sequences of human genes
Modrek, Barmak, Resch, Alissa, Grasso, Catherine, Lee, Christopher
We have identified 6201 alternative splice relationships in human genes, through a genome-wide analysis of expressed sequence tags (ESTs). Starting with ∼2.1 million human mRNA and EST sequences,...
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome
Xu, Qiang, Modrek, Barmak, Lee, Christopher
We have developed an automated method for discovering tissue-specific regulation of alternative splicing through a genome-wide analysis of expressed sequence tags (ESTs). Using this approach, we have...
ASAP: the Alternative Splicing Annotation Project
Lee, Christopher, Atanelov, Levan, Modrek, Barmak, Xing, Yi
Recently, genomics analyses have demonstrated that alternative splicing is widespread in mammalian genomes (30–60% of genes reported to have multiple isoforms), and may be one of their most...
Resch, Alissa, Xing, Yi, Alekseyenko, Alexander, Modrek, Barmak, Lee, Christopher
Recently there has been much interest in assessing the role of alternative splicing in evolution. We have sought to measure functional selection pressure on alternatively spliced single-exon skips,...
Genome-wide detection of alternative splicing in expressed sequences of human genes
Modrek, Barmak, Resch, Alissa, Grasso, Catherine, Lee, Christopher
We have identified 6201 alternative splice relationships in human genes, through a genome-wide analysis of expressed sequence tags (ESTs). Starting with ∼2.1 million human mRNA and EST sequences,...
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome
Xu, Qiang, Modrek, Barmak, Lee, Christopher
We have developed an automated method for discovering tissue-specific regulation of alternative splicing through a genome-wide analysis of expressed sequence tags (ESTs). Using this approach, we have...
ASAP: the Alternative Splicing Annotation Project
Lee, Christopher, Atanelov, Levan, Modrek, Barmak, Xing, Yi
Recently, genomics analyses have demonstrated that alternative splicing is widespread in mammalian genomes (30–60% of genes reported to have multiple isoforms), and may be one of their most...
Resch, Alissa, Xing, Yi, Alekseyenko, Alexander, Modrek, Barmak, Lee, Christopher
Recently there has been much interest in assessing the role of alternative splicing in evolution. We have sought to measure functional selection pressure on alternatively spliced single-exon skips,...