Gerben Ferwerda, Stephen E. Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Schouten, Jeroen A., Hulscher, Marlies E., Kullberg, Bart-Jan, Cox, Anton, Gyssens, Inge C., Van Der Meer, Jos W., ...
Objectives: To develop effective and targeted interventions to improve care for patients with community-acquired pneumonia (CAP), insight is needed into the factors that influence the quality of...
Schouten, Jeroen A., Hulscher, Marlies E., Kullberg, Bart-Jan, Cox, Anton, Gyssens, Inge C., Van Der Meer, Jos W., ...
Objectives: To develop effective and targeted interventions to improve care for patients with community-acquired pneumonia (CAP), insight is needed into the factors that influence the quality of...
Mannien, Judith, Kullberg, Bart-Jan, De Boer, Annette S., Nagelkerke, Nico J., Ridderhof, Marja, ...
Objectives: Misuse of antibiotics in surgical prophylaxis is still quite common. The objectives of this study were to reduce the quantity and improve the quality of surgical prophylaxis and to reduce...
Mannien, Judith, Kullberg, Bart-Jan, De Boer, Annette S., Nagelkerke, Nico J., Ridderhof, Marja, ...
Objectives: Misuse of antibiotics in surgical prophylaxis is still quite common. The objectives of this study were to reduce the quantity and improve the quality of surgical prophylaxis and to reduce...
Optimizing antimicrobial therapy. A method for antimicrobial drug me evaluation (1992)
GYSSENS, INGE C., VAN DEN BROEK, PIETER J., KULLBERG, BART-JAN, HEKSTER, YECHIEL A.
Aspergillus Meningitis: Diagnosis by Non-Culture-Based Microbiological Methods and Management
Verweij, Paul E., Brinkman, Kees, Kremer, Herbert P. H., Kullberg, Bart-Jan
The performance of antibody detection, antigen detection, and Aspergillus genus-specific PCR for diagnosing Aspergillus meningitis was investigated with 26 cerebrospinal fluid (CSF) samples obtained...
Stuyt, Rogier J. L., Netea, Mihai G., Kim, Soo-Hyun, Novick, Daniela, Rubinstein, Menachem, Kullberg, Bart-Jan, ...
The roles of endogenous cytokines induced by either intact staphylococcal microorganisms or staphylococcal exotoxins were examined using human whole-blood cultures. To accomplish this, interleukin-18...
Wanten, Geert J., Netea, Mihai G., Naber, Ton H., Curfs, Jo H., Jacobs, Liesbeth E., Verver-Jansen, Trees J., ...
Intravenous administration to volunteers of an emulsion of medium-chain lipids, but not of an emulsion of pure long-chain lipids or a placebo, increased the growth of Candida albicans in serum and...
From the Th1/Th2 Paradigm towards a Toll-Like Receptor/T-Helper Bias
Netea, Mihai G., Sutmuller, Roger P., Adema, Gosse J., Kullberg, Bart-Jan
NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis
Ferwerda, Gerben, Girardin, Stephen E, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk J., Langenberg, Dennis M. L, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Toll-like receptor 2 controls expansion and function of regulatory T cells
Sutmuller, Roger P.M., Kramer, Matthijs, Bennink, Erik J., Toonen, Liza W.J., Kullberg, Bart-Jan, ...
Tregs play a central role in the suppression of immune reactions and prevention of autoimmune responses harmful to the host. During acute infection, however, Tregs might hinder effector T cell...
Aspergillus Meningitis: Diagnosis by Non-Culture-Based Microbiological Methods and Management
Verweij, Paul E., Brinkman, Kees, Kremer, Herbert P. H., Kullberg, Bart-Jan
The performance of antibody detection, antigen detection, and Aspergillus genus-specific PCR for diagnosing Aspergillus meningitis was investigated with 26 cerebrospinal fluid (CSF) samples obtained...
Stuyt, Rogier J. L., Netea, Mihai G., Kim, Soo-Hyun, Novick, Daniela, Rubinstein, Menachem, Kullberg, Bart-Jan, ...
The roles of endogenous cytokines induced by either intact staphylococcal microorganisms or staphylococcal exotoxins were examined using human whole-blood cultures. To accomplish this, interleukin-18...
Wanten, Geert J., Netea, Mihai G., Naber, Ton H., Curfs, Jo H., Jacobs, Liesbeth E., Verver-Jansen, Trees J., ...
Intravenous administration to volunteers of an emulsion of medium-chain lipids, but not of an emulsion of pure long-chain lipids or a placebo, increased the growth of Candida albicans in serum and...
From the Th1/Th2 Paradigm towards a Toll-Like Receptor/T-Helper Bias
Netea, Mihai G., Sutmuller, Roger P., Adema, Gosse J., Kullberg, Bart-Jan
NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis
Ferwerda, Gerben, Girardin, Stephen E, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk J., Langenberg, Dennis M. L, ...
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...
Toll-like receptor 2 controls expansion and function of regulatory T cells
Sutmuller, Roger P.M., Kramer, Matthijs, Bennink, Erik J., Toonen, Liza W.J., Kullberg, Bart-Jan, ...
Tregs play a central role in the suppression of immune reactions and prevention of autoimmune responses harmful to the host. During acute infection, however, Tregs might hinder effector T cell...
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
Ferwerda, Bart, McCall, Matthew B. B., Alonso, Santos, Giamarellos-Bourboulis, Evangelos J., Mouktaroudi, Maria, Izagirre, Neskuts, ...
Infectious diseases exert a constant evolutionary pressure on the genetic makeup of our innate immune system. Polymorphisms in Toll-like receptor 4 (TLR4) have been related to susceptibility to...
Functional Consequences of Toll-like Receptor 4 Polymorphisms
Ferwerda, Bart, McCall, Matthew BB, Verheijen, Karlijn, Kullberg, Bart-Jan, Van Der Ven, André JAM, Van Der Meer, Jos WM, ...
Toll-like receptor 4 (TLR4) is an important pathogen recognition receptor that recognizes mainly lipopolysaccharide (LPS) of Gram-negative bacteria, but also structures from fungal and mycobacterial...
Dendritic Cell Interaction with Candida albicans Critically Depends on N-Linked Mannan*S⃞
Cambi, Alessandra, Netea, Mihai G., Mora-Montes, Hector M., Gow, Neil A. R., Hato, Stanleyson V., Lowman, Douglas W., ...
The fungus Candida albicans is the most common cause of mycotic infections in immunocompromised hosts. Little is known about the initial interactions between Candida and immune cell receptors,...
Dennehy, Kevin M, Ferwerda, Gerben, Faro-Trindade, Inês, Pyż, Elwira, Willment, Janet A, Taylor, Philip R, ...
Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others have proposed that pairs or sets of PRR...