Bart Wyns

Efficient tree traversal to reduce code growth in tree-based genetic programming (2009)

Wyns, Bart, Boullart, Luc

Genetic programming is an evolutionary optimization method following the principle of program induction. Genetic programming often uses variable-length tree structures for representing candidate...

Prediction of dose escalation for rheumatoid arthritis patients under infliximab treatment (2006)

Cruyssen, Bert Vander, Meeus, Jeroen, Wyns, Bart, Durez, Patrick, ...

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that leads to irreversible joint destruction. To prevent this, new biological therapies, such as infliximab, have been successfully...

Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity (2006)

Van Looy, Stijn, Wyns, Bart, Durez, Patrick, Van Den Bosch, Filip, ...

Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-alpha agents, few studies have examined the long-term effects. We evaluated 511 patients...

DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment (2005)

Van Looy, Stijn, Wyns, Bart, Durez, Patrick, Van Den Bosch, Filip, ...

This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3...