Hutchings, Matthew I., Crack, Jason C., Shearer, Neil, Thompson, Benjamin J., Thomson, Andrew J., Spiro, Stephen
The Paracoccus denitrificans transcription factor FnrP has been characterized using artificial FNR-dependent promoter-lacZ fusion plasmids in Escherichia coli. FnrP can activate both class I and...
Hutchings, Matthew I., Crack, Jason C., Shearer, Neil, Thompson, Benjamin J., Thomson, Andrew J., Spiro, Stephen
The Paracoccus denitrificans transcription factor FnrP has been characterized using artificial FNR-dependent promoter-lacZ fusion plasmids in Escherichia coli. FnrP can activate both class I and...
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, ...
Recent studies have shown that activating mutations of NOTCH1 are responsible for the majority of T cell acute lymphoblastic leukemia (T-ALL) cases. Most of these mutations truncate its C-terminal...