Evolution of the mammalian transcription factor binding repertoire via transposable elements (2008)
Bourque, Guillaume, Leong, Bernard, Vega, Vinsensius B., Chen, Xi, Lee, Yen Ling, Srinivasan, Kandhadayar G., ...
Identification of lineage-specific innovations in genomic control elements is critical for understanding transcriptional regulatory networks and phenotypic heterogeneity. We analyzed, from an...
Down, Thomas, Leong, Bernard, Hubbard, Tim JP
Abstract Background The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR proteins, which are...
Down, Thomas A., Leong, Bernard, Hubbard, Tim J. P.
Background: Exonic splice enhancers are sequences embedded within exons which promote and regulate the splicing of the transcript in which they are located. A class of exonic splice enhancers are the...
Spin-Torsion, Braneworlds and Changing Symmetry in the Universe (2003)
In this thesis, we explore three phenomenological alternatives to the current paradigm of the standard inflationary big bang scenario. The three alternative themes are spin torsion (or...
Gravitational Binding, Virialization and the Peculiar Velocity Distribution of the Galaxies (2003)
Leong, Bernard, Saslaw, William
We examine the peculiar velocity distribution function of galaxies in cosmological many-body gravitational clustering. Our statistical mechanical approach derives a previous basic assumption and...
Braneworld Tensor Anisotropies in the CMB (2002)
Leong, Bernard, Challinor, Anthony, Maartens, Roy, Lasenby, Anthony
Cosmic microwave background (CMB) observations provide in principle a high-precision test of models which are motivated by M theory. We set out the framework of a program to compute the tensor...
(1+3) Covariant Dynamics of Scalar Perturbations in Braneworlds (2001)
Leong, Bernard, Dunsby, Peter, Challinor, Anthony, Lasenby, Anthony
We discuss the dynamics of linear, scalar perturbations in an almost Friedmann-Robertson-Walker braneworld cosmology of Randall-Sundrum type II using the 1+3 covariant approach. We derive a complete...
Xu, Jun, Srinivas, Bhylahalli P., Tay, Shang Yew, Mak, Alicia, Yu, Xianwen, Lee, Serene G. P., ...
Hedgehog proteins play critical roles in organizing the embryonic development of animals, largely through modulation of target gene expression. Little is currently known, however, about the kinds and...
Evolution of the mammalian transcription factor binding repertoire via transposable elements
Bourque, Guillaume, Leong, Bernard, Vega, Vinsensius B., Chen, Xi, Lee, Yen Ling, Srinivasan, Kandhadayar G., ...
Identification of lineage-specific innovations in genomic control elements is critical for understanding transcriptional regulatory networks and phenotypic heterogeneity. We analyzed, from an...