Scientific Commons: Bernard Rossi

Modified vaccinia virus Ankara as a vaccine against feline coronavirus: immunogenicity and efficacy (2004)

Duquesne, Véronique, Cronier, Joëlle, Rossi, Bernard

Feline infectious peritonitis virus (FIPV) is a coronavirus that induces a fatal systemic disease mediated by an inappropriate immune response. Most previous vaccination attempts against FIPV were...

Re: Cytosine Deaminase/5-Fluorocytosine-Based Vaccination Against Liver Tumors: Evidence of Distant Bystander Effect (2000)

Pierrefite-Carle, Valérie, Gavelli, Adolfo, Brossette, Nicole, Baqué, Patrick, Benchimol, Daniel, Bourgeon, André, ...

Cytosine Deaminase/5-Fluorocytosine-Based Vaccination Against Liver Tumors: Evidence of Distant Bystander Effect (1999)

Pierrefite-Carle, Valérie, Baqué, Patrick, Gavelli, Adolfo, Mala, Marcel, Chazal, Maurice, Gugenheim, Jean, ...

BACKGROUND: The cytosine deaminase gene of Escherichia coli converts the nontoxic compound 5-fluorocytosine into 5-fluorouracil (5-FU), thereby acting as a suicide gene when introduced into cancer...

Increased Escherichia coli Phagocytosis in Neutrophils That Have Transmigrated across a Cultured Intestinal Epithelium

Hofman, Paul, Piche, Marjorie, Far, Dariush Farahi, Le Negrate, Gaëlle, Selva, Eric, Landraud, Luce, ...

The functionality of polymorphonuclear leukocytes (PMNs) once they migrate into the digestive lumen is still ill defined. More specifically, phagocytic function and bactericidal action of PMNs after...

Implication of Mitogen-Activated Protein Kinases in T84 Cell Responses to Enteropathogenic Escherichia coli Infection

Czerucka, Dorota, Dahan, Stéphanie, Mograbi, Baharia, Rossi, Bernard, Rampal, Patrick

Enteropathogenic Escherichia coli (EPEC) infection of T84 cells induces a decrease in transepithelial resistance, the formation of attaching and effacing (A/E) lesions, and cytokine production. The...

Epithelial Intestinal Cell Apoptosis Induced by Helicobacter pylori Depends on Expression of the cag Pathogenicity Island Phenotype

Le'Negrate, Gaëlle, Ricci, Vittorio, Hofman, Véronique, Mograbi, Baharia, Hofman, Paul, Rossi, Bernard

Helicobacter pylori has been shown to induce chronic active gastritis and peptic ulcer and may contribute to the development of duodenal ulcer. Previous studies have shown that H. pylori mediates...

The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis

Mograbi, Baharia, Bocciardi, Renata, Bourget, Isabelle, Juhel, Thierry, Farahi-Far, Dariush, Romeo, Giovanni, ...

Hirschsprung's disease (HSCR), a frequent developmental defect of the enteric nervous system is due to loss-of-function mutations of RET, a receptor tyrosine kinase essential for the mediation of...

Saccharomyces boulardii Preserves the Barrier Function and Modulates the Signal Transduction Pathway Induced in Enteropathogenic Escherichia coli-Infected T84 Cells

Czerucka, Dorota, Dahan, Stephanie, Mograbi, Baharia, Rossi, Bernard, Rampal, Patrick

Use of the nonpathogenic yeast Saccharomyces boulardii in the treatment of infectious diarrhea has attracted growing interest. The present study designed to investigate the effect of this yeast on...

Effect of Helicobacter pylori on Polymorphonuclear Leukocyte Migration across Polarized T84 Epithelial Cell Monolayers: Role of Vacuolating Toxin VacA and cag Pathogenicity Island

Hofman, Véronique, Ricci, Vittorio, Galmiche, Antoine, Brest, Patrick, Auberger, Patrick, Rossi, Bernard, ...

Helicobacter pylori infection can induce polymorphonuclear leukocyte (PMNL) infiltration of the gastric mucosa, which characterizes acute chronic gastritis. The mechanisms underlying this process are...

Escherichia coli Cytotoxic Necrotizing Factor 1 Effaces Microvilli and Decreases Transmigration of Polymorphonuclear Leukocytes in Intestinal T84 Epithelial Cell Monolayers

Hofman, Paul, Flatau, Gilles, Selva, Eric, Gauthier, Michel, Le Negrate, Gaëlle, Fiorentini, Carla, ...

Cytotoxic necrotizing factor type 1 (CNF1), a 110-kDa toxin-like protein from pathogenic Escherichia coli strains, induces an actin cytoskeleton reorganization consisting of the formation of...

Rho GTPase Is Activated by Cytotoxic Necrotizing Factor 1 in Peripheral Blood T Lymphocytes: Potential Cytotoxicity for Intestinal Epithelial Cells

Brest, Patrick, Mograbi, Baharia, Hofman, Véronique, Loubat, Agnès, Rossi, Bernard, Auberger, Patrick, ...

Some strains of Escherichia coli related to acute cystitis or colitis produce a toxin named cytotoxic necrotizing factor 1 (CNF-1). CNF-1 mediates its effects on epithelial cells or phagocytes via...

The Afa/Dr Adhesins of Diffusely Adhering Escherichia coli Stimulate Interleukin-8 Secretion, Activate Mitogen-Activated Protein Kinases, and Promote Polymorphonuclear Transepithelial Migration in T84 Polarized Epithelial Cells

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Bernet-Camard, Marie-Françoise, Rossi, Bernard, ...

Afa/Dr diffusely adhering Escherichia coli (Afa/Dr DAEC) strains cause symptomatic urinary tract and intestinal infections. The proinflammatory effects of Afa/Dr DAEC strains in vitro have been not...

Afa/Dr Diffusely Adhering Escherichia coli Infection in T84 Cell Monolayers Induces Increased Neutrophil Transepithelial Migration, Which in Turn Promotes Cytokine-Dependent Upregulation of Decay-Accelerating Factor (CD55), the Receptor for Afa/Dr Adhesins

Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Kansau, Imad, Rossi, Bernard, ...

Ulcerative colitis and Crohn's disease are inflammatory bowel diseases thought to involve strains of Escherichia coli. We report here that two wild-type Afa/Dr diffusely adhering E. coli (DAEC)...

Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the Mr 95,000 receptor subunit is its own kinase

Van Obberghen, Emmanuel, Rossi, Bernard, Kowalski, Aline, Gazzano, Helene, Ponzio, Gilles

Insulin stimulates the phosphorylation of its own receptor. In the work reported here, the kinase activity responsible for the insulin-stimulated phosphorylation of the insulin receptor was...