Jiirgen Klingelhofer, Bastian Conrad, Reiner Benecke, Bernd Frank
The combination of a carotid-basilar and a vertebro-vertebral collateral circulation was verified directly in a patient with a complete subclavian steal by means of transcranial Doppler...
SNPs in ultraconserved elements and familial breast cancer risk (2008)
Yang, Rongxi, Frank, Bernd, Hemminki, Kari, Bartram, Claus R., Wappenschmidt, Barbara, Sutter, Christian, ...
Ultraconserved elements (UCEs) are segments of >200 bp length showing absolute sequence identity between orthologous regions of human, rat and mouse genomes. The selection factors acting on these...
Association of a Common AKAP9 Variant With Breast Cancer Risk: A Collaborative Analysis (2008)
Frank, Bernd, Wiestler, Miriam, Kropp, Silke, Hemminki, Kari, Spurdle, Amanda B., Sutter, Christian, ...
Data from several studies have suggested that polymorphisms in A-kinase anchoring proteins (AKAPs), which are key components of signal transduction, contribute to carcinogenesis. To evaluate the...
Frank, Bernd, Bermejo, Justo Lorenzo, Hemminki, Kari, Sutter, Christian, Wappenschmidt, Barbara, Meindl, Alfons, ...
Copy number variants (CNVs), insertions, deletions and duplications, contribute considerably to human genetic variation and disease development. A recent study has characterized 100 CNVs including a...
BRIP1 (BACH1) variants and familial breast cancer risk: a case-control study (2007)
Frank, Bernd, Hemminki, Kari, Meindl, Alfons, Wappenschmidt, Barbara, Sutter, Christian, Kiechle, Marion, ...
Abstract Background Inactivating and truncating mutations of the nuclear BRCA1-interacting protein 1 (BRIP1) have been shown to be the major cause of Fanconi anaemia and, due to subsequent...
Frank, Bernd, Bermejo, Justo Lorenzo, Hemminki, Kari, Sutter, Christian, Wappenschmidt, Barbara, Meindl, Alfons, ...
Copy number variants (CNVs) - insertions, deletions and duplications - contribute considerably to human genetic variation and disease development. A recent study has characterized 100 CNVs, including...
Burwinkel, Barbara, Shanmugam, Kalai S, Hemminki, Kari, Meindl, Alfons, Schmutzler, Rita K, Sutter, Christian, ...
Abstract Background The transcription factor 7-like 2 (TCF7L2) is a critical component of the Wnt/β-catenin pathway. Aberrant TCF7L2 expression modifies Wnt signaling and mediates oncogenic effects...
Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer (2006)
Wirtenberger, Michael, Frank, Bernd, Hemminki, Kari, Klaes, Rüdiger, Schmutzler, Rita K., Wappenschmidt, Barbara, ...
Mutations of the human RecQ helicase genes WRN and BLM lead to rare autosomal recessive disorders, Werner and Bloom syndromes, which are associated with premature ageing and cancer predisposition. We...
Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer (2006)
Wirtenberger, Michael, Frank, Bernd, Hemminki, Kari, Klaes, Rüdiger, Schmutzler, Rita K., Wappenschmidt, Barbara, ...
Mutations of the human RecQ helicase genes WRN and BLM lead to rare autosomal recessive disorders, Werner and Bloom syndromes, which are associated with premature ageing and cancer predisposition. We...
Frank, Bernd, Hemminki, Kari, Wappenschmidt, Barbara, Meindl, Alfons, Klaes, Rüdiger, Schmutzler, Rita K., ...
Dysregulation of apoptosis plays a crucial role in carcinogenesis. As part of death receptor- and mitochondrion-mediated apoptosis, the homologues caspases 10 and 8 may act as low-penetrance breast...
Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer (2006)
Wirtenberger, Michael, Frank, Bernd, Hemminki, Kari, Klaes, Rüdiger, Schmutzler, Rita K., Wappenschmidt, Barbara, ...
Mutations of the human RecQ helicase genes WRN and BLM lead to rare autosomal recessive disorders, Werner and Bloom syndromes, which are associated with premature ageing and cancer predisposition. We...
TP53-binding protein variants and breast cancer risk: a case-control study (2005)
Frank, Bernd, Hemminki, Kari, Bermejo, Justo, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, ...
Abstract Introduction The TP53-binding protein (53BP1) has been shown to influence TP53-mediated transcriptional activation, thus playing a pivotal role in DNA damage signalling. Genetic aberrations...
Re: Association of a Common Variant of the CASP8 Gene With Reduced Risk of Breast Cancer (2005)
Frank, Bernd, Bermejo, Justo Lorenzo, Hemminki, Kari, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, ...
The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk (2005)
Frank, Bernd, Hemminki, Kari, Wirtenberger, Michael, Bermejo, Justo Lorenzo, Bugert, Peter, Klaes, Rüdiger, ...
Overexpression of the proto-oncogene ERBB2 (HER2/NEU) has been observed in 20–30% of breast cancers involving poor prognosis. Genetic alterations within ERBB2 have been shown to induce...
Association of death receptor 4 haplotype 626C-683C with an increased breast cancer risk (2005)
Frank, Bernd, Hemminki, Kari, Shanmugam, Kalai S., Meindl, Alfons, Klaes, Rüdiger, Schmutzler, Rita K., ...
Dysregulation of apoptosis plays a crucial role in carcinogenesis. Tumour necrosis factor-related apoptosis-inducing ligand stimulates the extrinsic apoptotic pathway by binding to death receptor 4...
Association of death receptor 4 haplotype 626C-683C with an increased breast cancer risk (2005)
Frank, Bernd, Hemminki, Kari, Shanmugam, Kalai S., Meindl, Alfons, Klaes, Rüdiger, Schmutzler, Rita K., ...
Dysregulation of apoptosis plays a crucial role in carcinogenesis. Tumour necrosis factor-related apoptosis-inducing ligand TRAIL stimulates the extrinsic apoptotic pathway by binding to death...
Frank, Bernd, Hemminki, Kari, Wappenschmidt, Barbara, Meindl, Alfons, Klaes, Rüdiger, Schmutzler, Rita K., ...
Dysregulation of apoptosis plays a crucial role in carcinogenesis. As part of death receptor- and mitochondrion-mediated apotosis, the homologues caspase-10 and caspase-8 may act as low-penetrance...
The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk (2004)
Frank, Bernd, Hemminki, Kari, Wirtenberger, Michael, Bermejo, Justo Lorenzo, Bugert, Peter, Klaes, Rüdiger, ...
Overexpression of the proto-oncogene ERBB2 (HER2/NEU) has been observed in 20-30 % of breast cancers involving poor prognosis. Genetic alterations within ERBB2 have been shown to induce...
Heidelberg, Univ., Diss., 2003.
Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
Potsdam, Univ., Diss., 1994.
Hannover, Med. Hochsch., Habil-Schr., 1993.
Frank, Bernd., Mogalle, Heinz-A.
Hannover, Med. Hochsch., Diss., 1985 (Nicht f.d. Austausch).
Heidelberg, Univ., Diss., 1982 (Nicht f.d. Austausch).
Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
TP53-binding protein variants and breast cancer risk: a case-control study
Frank, Bernd, Hemminki, Kari, Bermejo, Justo Lorenzo, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, ...
Burwinkel, Barbara, Shanmugam, Kalai S, Hemminki, Kari, Meindl, Alfons, Schmutzler, Rita K, Sutter, Christian, ...
Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...
Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...
TP53-binding protein variants and breast cancer risk: a case-control study
Frank, Bernd, Hemminki, Kari, Bermejo, Justo Lorenzo, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, ...