Bernice Marcus-Samuels

Torpor in mice is induced by both leptin-dependent and -independent mechanisms

Gavrilova, Oksana, Leon, Lisa R., Marcus-Samuels, Bernice, Mason, Mark M., Castle, Arthur L., Refetoff, Samuel, ...

We tested the effect of chronic leptin treatment on fasting-induced torpor in leptin-deficient A-ZIP/F-1 and ob/ob mice. A-ZIP/F-1 mice have virtually no white adipose tissue and low leptin levels,...

Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates

Hardikar, Anandwardhan A., Marcus-Samuels, Bernice, Geras-Raaka, Elizabeth, Raaka, Bruce M., Gershengorn, Marvin C.

Development of the endocrine pancreas includes a series of early events wherein precursor cells cluster, that is migrate to form cell aggregates, which subsequently differentiate into islets of...

Life without white fat: a transgenic mouse

Moitra, Jaideep, Mason, Mark M., Olive, Michelle, Krylov, Dmitry, Gavrilova, Oksana, Marcus-Samuels, Bernice, ...

We have generated a transgenic mouse with no white fat tissue throughout life. These mice express a dominant-negative protein, termed A-ZIP/F, under the control of the adipose-specific aP2...

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

Gavrilova, Oksana, Marcus-Samuels, Bernice, Graham, David, Kim, Jason K., Shulman, Gerald I., Castle, Arthur L., ...

In lipoatrophic diabetes, a lack of fat is associated with insulin resistance and hyperglycemia. This is in striking contrast to the usual association of diabetes with obesity. To understand the...

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

Chao, Lily, Marcus-Samuels, Bernice, Mason, Mark M., Moitra, Jaideep, Vinson, Charles, Arioglu, Elif, ...

There is uncertainty about the site(s) of action of the antidiabetic thiazolidinediones (TZDs). These drugs are agonist ligands of the transcription factor PPARγ, which is abundant in adipose tissue...

Torpor in mice is induced by both leptin-dependent and -independent mechanisms

Gavrilova, Oksana, Leon, Lisa R., Marcus-Samuels, Bernice, Mason, Mark M., Castle, Arthur L., Refetoff, Samuel, ...

We tested the effect of chronic leptin treatment on fasting-induced torpor in leptin-deficient A-ZIP/F-1 and ob/ob mice. A-ZIP/F-1 mice have virtually no white adipose tissue and low leptin levels,...

Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates

Hardikar, Anandwardhan A., Marcus-Samuels, Bernice, Geras-Raaka, Elizabeth, Raaka, Bruce M., Gershengorn, Marvin C.

Development of the endocrine pancreas includes a series of early events wherein precursor cells cluster, that is migrate to form cell aggregates, which subsequently differentiate into islets of...

Life without white fat: a transgenic mouse

Moitra, Jaideep, Mason, Mark M., Olive, Michelle, Krylov, Dmitry, Gavrilova, Oksana, Marcus-Samuels, Bernice, ...

We have generated a transgenic mouse with no white fat tissue throughout life. These mice express a dominant-negative protein, termed A-ZIP/F, under the control of the adipose-specific aP2...

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

Gavrilova, Oksana, Marcus-Samuels, Bernice, Graham, David, Kim, Jason K., Shulman, Gerald I., Castle, Arthur L., ...

In lipoatrophic diabetes, a lack of fat is associated with insulin resistance and hyperglycemia. This is in striking contrast to the usual association of diabetes with obesity. To understand the...

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

Chao, Lily, Marcus-Samuels, Bernice, Mason, Mark M., Moitra, Jaideep, Vinson, Charles, Arioglu, Elif, ...

There is uncertainty about the site(s) of action of the antidiabetic thiazolidinediones (TZDs). These drugs are agonist ligands of the transcription factor PPARγ, which is abundant in adipose tissue...