Bertil Johansson

Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: rare T-cell receptor gene rearrangements are associated with poor outcome (2009)

Karrman, Kristina, Forestier, Erik, Heyman, Mats, Andersen, Mette K, Autio, Kirsi, Blennow, Elisabeth, ...

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The DNA methylome of pediatric acute lymphoblastic leukemia (2009)

Davidsson, Josef, Lilljebjörn, Henrik, Andersson, Anna, Veerla, Srinivas, Heldrup, Jesper, Behrendtz, Mikael, ...

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, with high hyperdiploidy [51–67 chromosomes] and the t(12;21)(p13;q22) [ETV6/RUNX1 fusion] representing the most frequent...

Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression (2008)

Hansson, Frida, Toporski, Jacek, Månsson, Robert, Johansson, Bertil, Norén-Nyström, Ulrika, Jacobsen, Sten, ...

Abstract Background Childhood pre-B acute lymphoblastic leukemia (ALL) is a bone marrow (BM) derived disease, which often disseminates out of the BM cavity, where malignant cells to a variable degree...

Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival. (2008)

Forestier, Erik, Heyman, Mats, Andersen, Mette K, Autio, Kirsi, Blennow, Elisabeth, Borgström, Georg, ...

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Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-cell precursor acute lymphoblastic leukemias: a Nordic series of 24 cases and review of the literature (2008)

Forestier, Erik, Gauffin, Fredrika, Andersen, Mette K, Autio, Kirsi, Borgström, Georg, Golovleva, Irina, ...

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Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3 (2007)

Davidsson, Josef, Andersson, Anna, Paulsson, Kajsa, Heidenblad, Markus, Isaksson, Margareth, Borg, Åke, ...

Although gain of 1q occurs in 25% of Burkitt lymphomas (BLs) and 10% of pediatric high hyperdiploid acute lymphoblastic leukemias (ALLs), little is known about the origin, molecular genetic...

Cytogenetic patterns in ETV6/RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia: A Nordic series of 245 cases and review of the literature. (2007)

Forestier, Erik, Andersen, Mette K, Autio, Kirsi, Blennow, Elisabeth, Borgström, Georg, Golovleva, Irina, ...

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Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12). (2007)

Panagopoulos, Ioannis, Kerndrup, Gitte, Carlsen, Niels, Strombeck, Bodil, Isaksson, Margareth, Johansson, Bertil

Abstract is not available

Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome. (2007)

Agerstam, Helena, Lilljebjorn, Henrik, Lassen, Carin, Swedin, Agneta, Richter, Johan, Vandenberghe, Peter, ...

Abstract is not available

The impact of translocations and gene fusions on cancer causation. (2007)

Mitelman, Felix, Johansson, Bertil, Mertens, Fredrik

Abstract is not available

Characterisation of genomic translocation breakpoints and identification of an alternative TCF3/PBX1 fusion transcript in t(1;19)(q23;p13)-positive acute lymphoblastic leukaemias. (2007)

Paulsson, Kajsa, Jonson, Tord, Ora, Ingrid, Olofsson, Tor, Panagopoulos, Ioannis, Johansson, Bertil

Abstract is not available

Tiling resolution array CGH, expression, and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3. (2007)

Davidsson, Josef, Andersson, Anna, Paulsson, Kajsa, Heidenblad, Markus, Isaksson, Margareth, Borg, Ake, ...

Abstract is not available

The molecular signature of MDS stem cells supports a stem cell origin of 5q- myelodysplastic syndromes. (2007)

Nilsson, Lars, Eden, Patrik, Olsson, Eleonor, Mansson, Robert, Astrand-Grundstrom, Ingbritt, Strombeck, Bodil, ...

Abstract is not available

FLT3 mutations in a 10 year consecutive series of 177 childhood acute leukemias and their impact on global gene expression patterns. (2007)

Andersson, Anna, Paulsson, Kajsa, Lilljebjorn, Henrik, Lassen, Carin, Strombeck, Bodil, Heldrup, Jesper, ...

Abstract is not available

Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia. (2007)

Paulsson, Kajsa, Horvat, Andrea, Strombeck, Bodil, Nilsson, Fredrik, Heldrup, Jesper, Behrendtz, Mikael, ...

Abstract is not available

clustered near-centromeric breakpoints and overexpression of genes (2007)

Josef Davidsson, Anna Andersson, Kajsa Paulsson, Markus Heidenblad, Åke Borg, Jesper Heldrup, ...

Tiling resolution array CGH, expression, and methylation analyses of dup(1q) in Burkitt

Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia. (2006)

Karrman, Kristina, Andersson, Anna, Bjorgvinsdóttir, Helga, Strombeck, Bodil, Lassen, Carin, Olofsson, Tor, ...

Abstract is not available

Fusion of ETV6 with an intronic sequence of the BAZ2A gene in a paediatric pre-B acute lymphoblastic leukaemia with a cryptic chromosome 12 rearrangement. (2006)

Panagopoulos, Ioannis, Strombeck, Bodil, Isaksson, Margareth, Heldrup, Jesper, Olofsson, Tor, Johansson, Bertil

Abstract is not available

Array-based comparative genomic hybridization characterization of cytogenetically polyclonal myeloid malignancies. (2006)

Davidsson, Josef, Heidenblad, Markus, Borg, Ake, Johansson, Bertil

Abstract is not available.

High incidence of the ETV6/RUNX1 fusion gene in paediatric precursor B-cell acute lymphoblastic leukaemias with trisomy 21 as the sole cytogenetic change: a Nordic series of cases diagnosed 1989-2005. (2006)

Karrman, Kristina, Forestier, Erik, Andersen, Mette K, Autio, Kirsi, Borgstrom, Georg, Heim, Sverre, ...

Abstract is not available

MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene (2006)

Storlazzi, Clelia Tiziana, Fioretos, Thoas, Surace, Cecilia, Lonoce, Angelo, Mastrorilli, Angela, Strömbeck, Bodil, ...

Double minutes (dmin)—circular, extra-chromosomal amplifications of specific acentric DNA fragments—are relatively frequent in malignant disorders, particularly in solid tumors. In acute myeloid...

MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene (2006)

Storlazzi, Clelia Tiziana, Fioretos, Thoas, Surace, Cecilia, Lonoce, Angelo, Mastrorilli, Angela, Strömbeck, Bodil, ...

Double minutes (dmin) - circular, extrachromosomal amplifications of specific acentric DNA fragments - are relatively frequent in malignant disorders, particularly in solid tumors. In acute myeloid...

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia. (2005)

Castor, Anders, Nilsson, Lars, Astrand-Grundström, Ingbritt, Buitenhuis, Miranda, Ramirez, Carole, Anderson, Kristina, ...

Abstract is not available

Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected patients with neoplastic disorders. (2005)

Mitelman, Felix, Mertens, Fredrik, Johansson, Bertil

Abstract is not available

Evidence for a single-step mechanism in the origin of hyperdiploid childhood acute lymphoblastic leukemia. (2005)

Paulsson, Kajsa, Mörse, Helena, Fioretos, Thoas, Behrendtz, Mikael, Strömbeck, Bodil, Johansson, Bertil

Abstract is not available

Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations. (2005)

Andersson, Anna, Olofsson, Tor, Lindgren, David, Nilsson, Bjorn, Ritz, Cecilia, Edén, Patrik, ...

Abstract is not available

Multicolor fluorescence in situ hybridization characterization of cytogenetically polyclonal hematologic malignancies. (2005)

Davidsson, Josef, Paulsson, Kajsa, Johansson, Bertil

Abstract is not available

Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients (2004)

Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...

Abstract Background Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths in the Western world, and despite the fact that metastases are usually the ultimate cause of...

The Breakpoint Region of the Most Common Isochromosome, i(17q), in Human Neoplasia Is Characterized by a Complex Genomic Architecture with Large, Palindromic, Low-Copy Repeats. (2004)

Barbouti, Aikaterini, Stankiewicz, Pawel, Nusbaum, Chad, Cuomo, Christina, Cook, April, Höglund, Mattias, ...

Abstract is not available

Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients. (2004)

Andersson, Anna, Johansson, Bertil, Lassen, Carin, Mitelman, Felix, Billström, Rolf, Fioretos, Thoas

Abstract is not available

Identification of a commonly amplified 4.3 Mb region with overexpression of the C8FW gene, encoding a phosphoprotein regulated by mitogenic pathways, but not of the MYC gene in MYC-containing double minutes in myeloid malignancies. (2004)

Storlazzi, Clelia T., Fioretos, Thoas, Paulsson, Kajsa, Strömbeck, Bodil, Lassen, Carin, Ahlgren, Tomas, ...

Abstract is not available

High frequencies of chromosomal aberrations in multiple myeloma and monoclonal gammopathy of undetermined significance in direct chromosome preparation. (2004)

Nilsson, Therese, Lenhoff, Stig, Rylander, Lars, Höglund, Mattias, Turesson, Ingemar, Mitelman, Felix, ...

Abstract is not available

MLL/GRAF fusion in an infant acute monocytic leukemia (AML M5b) with a cytogenetically cryptic ins(5;11)(q31;q23q23). (2004)

Panagopoulos, Ioannis, Kitagawa, Ashly, Isaksson, Margareth, Mörse, Helena, Mitelman, Felix, Johansson, Bertil

Abstract is not available

MDS/AML-associated cytogenetic abnormalities in multiple myeloma and monoclonal gammopathy of undetermined significance: Evidence for frequent de novo occurrence and multipotent stem cell involvement of del(20q). (2004)

Nilsson, Therese, Nilsson, Lars, Lenhoff, Stig, Rylander, Lars, Astrand-Grundström, Ingbritt, Strömbeck, Bodil, ...

Abstract is not available

Formation of der(19)t(1;19)(q23;p13) in acute lymphoblastic leukemia. (2004)

Paulsson, Kajsa, Horvat, Andrea, Fioretos, Thoas, Mitelman, Felix, Johansson, Bertil

Abstract is not available

Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia. (2004)

Johansson, Bertil, Mertens, Fredrik, Mitelman, Felix

Abstract is not available

Identification of a commonly amplified 4.3 Mb region with overexpression of the C8FW gene, encoding a phosphoprotein regulated by mitogenic pathways, but not of the MYC gene in MYC-containing double minutes in myeloid malignancies (2004)

Storlazzi, Clelia T., Fioretos, Thoas, Paulsson, Kajsa, Strömbeck, Bodil, Lassen, Carin, Ahlgren, Tomas, ...

Double minutes (dmin), the cytogenetic hallmark of genomic amplification, are found in approximately 1% of karyotypically abnormal acute myeloid leukemias (AML) and myelodysplastic syndromes (MDS)....

Identification of a commonly amplified 4.3 Mb region with overexpression of C8FW, but not MYC in MYC-containing double minutes in myeloid malignancies (2004)

Storlazzi, Clelia T., Fioretos, Thoas, Paulsson, Kajsa, Strömbeck, Bodil, Lassen, Carin, Ahlgren, Tomas, ...

Double minutes (dmin), the cytogenetic hallmark of genomic amplification, are found in ∼1% of karyotypically abnormal acute myeloid leukemias (AML) and myelodysplastic syndromes (MDS). The...

Identification of a commonly amplified 4.3 Mb region with overexpression of the C8FW gene, encoding a phosphoprotein regulated by mitogenic pathways, but not of the MYC gene in MYC-containing double minutes in myeloid malignancies (2004)

Storlazzi, Clelia T., Fioretos, Thoas, Paulsson, Kajsa, Strömbeck, Bodil, Lassen, Carin, Ahlgren, Tomas, ...

Double minutes (dmin), the cytogenetic hallmark of genomic amplification, are found in approximately 1% of karyotypically abnormal acute myeloid leukemias (AML) and myelodysplastic syndromes (MDS)....

Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13). (2003)

Panagopoulos, Ioannis, Isaksson, Margareth, Billström, Rolf, Strömbeck, Bodil, Mitelman, Felix, Johansson, Bertil

Abstract is not available

Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13). (2003)

Panagopoulos, Ioannis, Isaksson, Margareth, Lindvall, Charlotta, Hagemeijer, Anna, Mitelman, Felix, Johansson, Bertil

Abstract is not available

Trisomy 8 as the sole chromosomal aberration in myelocytic malignancies. a multicolor and locus-specific fluorescence in situ hybridization study. (2003)

Paulsson, Kajsa, Fioretos, Thoas, Strömbeck, Bodil, Mauritzson, Nils, Tanke, Hans J, Johansson, Bertil

Abstract is not available

A Novel Gene, MSI2, Encoding a Putative RNA-binding Protein Is Recurrently Rearranged at Disease Progression of Chronic Myeloid Leukemia and Forms a Fusion Gene with HOXA9 as a Result of the Cryptic t(7;17)(p15;q23). (2003)

Barmpouti, Aikaterini, Höglund, Mattias, Johansson, Bertil, Lassen, Carin, Nilsson, Per-Gunnar, Hagemeijer, Anne, ...

Abstract is not available

A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age- and sex-related differences. (2003)

Nilsson, Thérèse, Höglund, Mattias, Lenhoff, Stig, Rylander, Lars, Turesson, Ingemar, Westin, Jan, ...

The cytogenetic features (ploidy, complexity, breakpoints, imbalances) were ascertained in 783 abnormal multiple myeloma (MM) cases to identify frequently involved chromosomal regions as well as a...

Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1. (2003)

Jonson, Tord, Heidenblad, Markus, Håkansson, Petra, Gorunova, Ludmila, Johansson, Bertil, Fioretos, Thoas, ...

Abstract is not available

Cytogenetic abnormalities in childhood acute myeloid leukaemia: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001. (2003)

Forestier, Erik, Heim, Sverre, Blennow, Elisabeth, Borgström, Georg, Holmgren, Gösta, Heinonen, Kristiina, ...

Abstract is not available

The formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia. (2003)

Paulsson, Kajsa, Panagopoulos, Ioannis, Knuutila, Sakari, Jee, Kowan J, Garwicz, Stanislaw, Fioretos, Thoas, ...

Abstract is not available

Clinical and genetic studies of ETV6/ABL1-positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate. (2003)

Barbouti, Aikaterini, Ahlgren, Tomas, Johansson, Bertil, Höglund, Mattias, Lassen, Carin, Turesson, Ingemar, ...

Most chronic myeloid leukaemia (CML) patients are genetically characterized by the t(9;22)(q34;q11), generating the BCR/ABL1 fusion gene. However, a few CML patients with rearrangements of 9q34 and...

Cytogenetic and morphologic subgroups of myelodysplastic syndromes in relation to occupational and hobby exposures. (2003)

Albin, Maria, Björk, Jonas, Welinder, Hans, Tinnerberg, Håkan, Mauritzson, Nils, Billström, Rolf, ...

OBJECTIVES: This study investigated the association between occupational and hobby exposure and the risk of myelodysplastic syndromes (MDS) while focusing on differential patterns of clonal...

Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia. (2003)

Paulsson, Kajsa, Panagopoulos, Ioannis, Knuutila, Sakari, Jee, Kowan Ja, Garwicz, Stanislaw, Fioretos, Thoas, ...

Abstract is not available

Cytogenetic and molecular genetic evolution of chronic myeloid leukemia. (2002)

Johansson, Bertil, Fioretos, Thoas, Mitelman, Felix

Chronic myeloid leukemia (CML) is genetically characterized by the presence of the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR/ABL gene fusion on the derivative chromosome 22 called...

Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification. (2002)

Heidenblad, Markus, Jonson, Tord, Mahlamäki, Eija H, Gorunova, Ludmila, Karhu, Ritva, Johansson, Bertil, ...

Previous cytogenetic and comparative genomic hybridization (CGH) analyses have shown that the gain of chromosome arm 12p is frequent in pancreatic carcinomas. We investigated 15 pancreatic carcinoma...

Expression of NUP98/TOP1, but not of TOP1/NUP98, in a treatment-related myelodysplastic syndrome with t(10;20;11)(q24;q11;p15). (2002)

Panagopoulos, Ioannis, Fioretos, Thoas, Isaksson, Margareth, Larsson, Gun, Billström, Rolf, Mitelman, Felix, ...

The t(11;20)(p15;q11) is a rare but recurrent translocation that so far has been described in only four acute myeloid leukemias (AMLs), two treatment-related myelodysplastic syndromes (t-MDSs), and...

Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8. (2002)

Nilsson, Lars, Astrand-Grundström, Ingbritt, Anderson, Kristina, Arvidsson, Ingrid, Hokland, Peter, Bryder, David, ...

Clonality studies of mature cells suggest that the primary transformation event in myelodysplastic syndrome (MDS) most frequently occurs in a myeloid-restricted progenitor, a hypothesis supported by...

Cytogenetic abnormalities in a hemangiopericytoma of the spleen. (2002)

Hallén, Magnus, Parada, Luis A, Gorunova, Ludmila, Pålsson, Birger, Dictor, Michael, Johansson, Bertil

To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid...

Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced translocations during disease progression. (2002)

Barbouti, Aikaterini, Johansson, Bertil, Höglund, Mattias, Mauritzson, Nils, Strömbeck, Bodil, Nilsson, Per-Gunnar, ...

During the initial indolent chronic phase of chronic myeloid leukemia (CML), the t(9;22)(q34;q11), resulting in the Philadelphia chromosome (Ph), is usually the sole cytogenetic anomaly, but as the...

RT-PCR analysis of acute myeloid leukemia with t(8;16)(p11;p13): Identification of a novel MOZ/CBP transcript and absence of CBP/MOZ expression. (2002)

Panagopoulos, Ioannis, Fioretos, Thoas, Isaksson, Margareth, Mitelman, Felix, Johansson, Bertil, Theorin, Niklas, ...

Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13) (2001)

Panagopoulos, Ioannis, Fioretos, Thoas, Isaksson, Margareth, Samuelsson, Ulf, Billström, Rolf, Strömbeck, Bodil, ...

The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We...

Religion and superstition in the plays of Ben Jonson and Thomas Middleton. (1950)

Johansson, Bertil.

Extra t.p. with thesis statement, inserted, has imprint: Uppsala, Almqvist & Wiksells boktr., 1950.

Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients

Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...

Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations

Andersson, Anna, Olofsson, Tor, Lindgren, David, Nilsson, Björn, Ritz, Cecilia, Edén, Patrik, ...

Global expression profiles of a consecutive series of 121 childhood acute leukemias (87 B lineage acute lymphoblastic leukemias, 11 T cell acute lymphoblastic leukemias, and 23 acute myeloid...

Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients

Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...

The Breakpoint Region of the Most Common Isochromosome, i(17q), in Human Neoplasia Is Characterized by a Complex Genomic Architecture with Large, Palindromic, Low-Copy Repeats

Barbouti, Aikaterini, Stankiewicz, Pawel, Nusbaum, Chad, Cuomo, Christina, Cook, April, Höglund, Mattias, ...

Although a great deal of information has accumulated regarding the mechanisms underlying constitutional DNA rearrangements associated with inherited disorders, virtually nothing is known about the...

Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations

Andersson, Anna, Olofsson, Tor, Lindgren, David, Nilsson, Björn, Ritz, Cecilia, Edén, Patrik, ...

Global expression profiles of a consecutive series of 121 childhood acute leukemias (87 B lineage acute lymphoblastic leukemias, 11 T cell acute lymphoblastic leukemias, and 23 acute myeloid...

Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression

Hansson, Frida, Toporski, Jacek, Månsson, Robert, Johansson, Bertil, Norén-Nyström, Ulrika, Jacobsen, Sten Eirik W, ...